Bb charge

[Guest guest]

Has only 2 membrane lipids in classical form - phosphatidylcholine and

one other. According to whoever. No LPS (which is anionic). Shafer and

think the probable paucity of surface proteins may also lead to a

lower charge.

However part of the negative surface charge of bacteria is generated

by their constant pumping out the cation H+ (ie a proton) as a part of

energy production. Therefore Bb will need to have some negative

surface charge.

Our mitochondria do the same. Therefore for any cell-penetrating

membrane attack cationics, nuking ones mitos is one conceivable concern

(?). Red cells also have a neg charge (presumably to aid them not

stickin all together) and are an oft-considered potential liability

for off-target effects of brane-attack cationics. Yet many of the

latter have " doable " or even quite low haemotoxicity, not sure why.

Sincerly,

Ueeghhcchh (ADs >> bruxism >> aspirin-refractory headache)

> so is lyme disease anionic, negative charge on surface like other

> bacteria?

[Guest guest]

Okay. Will email you.

> > so is lyme disease anionic, negative charge on surface like other

> > bacteria?

[Guest guest]

BY the way one investigation found Bb perfectly suceptible to purified

neutrophil cationics, another found it highly refractory. This

inconsistency interests me intensely as it could be due to

accidentally induced differences in the states of the organisms. (Or

alot of other things.)

[Guest guest]

Can you get me the citations.

This is completely confusing

C

> BY the way one investigation found Bb perfectly suceptible to

purified

> neutrophil cationics, another found it highly refractory. This

> inconsistency interests me intensely as it could be due to

> accidentally induced differences in the states of the organisms. (Or

> alot of other things.)