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Re: quinolinic acid

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So what is the problem that causes this, an enzyme deficiency,

neurotransmitter imbalance, heavy metal accumulation, or what? And

what overpriced supplement can I buy in the naive hope of helping the

situation?

> Hi,

>

> A 1992 paper in the journal Brain said, " We conclude that

inflammatory

> diseases are associated with accumulation of QUIN, kynurenic acid

and

> L-kynurenine within the central nervous system, but that the

available

> data do not support a role for QUIN in the aetiology of

Huntington's

> disease or Alzheimer's disease. "

>

> PMID: 1422788

>

> ==============================

>

> But this week, new findings were reported in Australia. One of the

> authors of a paper that appeared in the journal Neuropathology and

> Applied Neurobiology said this week, " We found that all of the

brains

> of dementia patients showed quinolinic acid neurotoxicity... "

>

> Another said, " We found that all of the brains of dementia

patients

> showed quinolinic acid neurotoxicity, " said Professor Bruce Brew,

> Director of Neurology at St 's Hospital and Professor of

> Medicine at the University of New South Wales (UNSW). " This acid

kills

> nerve cells in the brain, leading to brain dysfunction and

ultimately

> death. "

>

> " Quinolinic acid is part of a biochemical pathway called the

kynurenine

> pathway, " said the lead author of the research, UNSW's Dr Gilles

> Guillemin, who is based at the Centre for Immunology at St

's

> Hospital. " The activation of that pathway is also found in other

major

> brain diseases including Huntington's disease, stroke, dementia

and

> schizophrenia. "

>

> http://www.rxpgnews.com/research/aging/dementia/alzheimers/

> article_1994.shtml

> ======================

>

> Thanks to Tony for pointing out the Australian findings.

>

> Sue ,

> Upstate New Yorark

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Shakerz

The toxins can be the result of an occult infection that isn't being

considered.The mouth is full of oppurtunistic toxin producing

bacteria that don't have a long way to travel to dump things into

the brain. As you can see the studies are so promising, and they

make the news, and they disappear for years after that.

I suppose a normal body may detox thru sweating and just normal

blood flow pathways, we seem a little under done in a lot of area's.

I'm sure blood volume may help keep things flowing as opposed to

stagnating.

> > Hi,

> >

> > A 1992 paper in the journal Brain said, " We conclude that

> inflammatory

> > diseases are associated with accumulation of QUIN, kynurenic

acid

> and

> > L-kynurenine within the central nervous system, but that the

> available

> > data do not support a role for QUIN in the aetiology of

> Huntington's

> > disease or Alzheimer's disease. "

> >

> > PMID: 1422788

> >

> > ==============================

> >

> > But this week, new findings were reported in Australia. One of

the

> > authors of a paper that appeared in the journal Neuropathology

and

> > Applied Neurobiology said this week, " We found that all of the

> brains

> > of dementia patients showed quinolinic acid neurotoxicity... "

> >

> > Another said, " We found that all of the brains of dementia

> patients

> > showed quinolinic acid neurotoxicity, " said Professor Bruce

Brew,

> > Director of Neurology at St 's Hospital and Professor of

> > Medicine at the University of New South Wales (UNSW). " This acid

> kills

> > nerve cells in the brain, leading to brain dysfunction and

> ultimately

> > death. "

> >

> > " Quinolinic acid is part of a biochemical pathway called the

> kynurenine

> > pathway, " said the lead author of the research, UNSW's Dr

Gilles

> > Guillemin, who is based at the Centre for Immunology at St

> 's

> > Hospital. " The activation of that pathway is also found in other

> major

> > brain diseases including Huntington's disease, stroke, dementia

> and

> > schizophrenia. "

> >

> > http://www.rxpgnews.com/research/aging/dementia/alzheimers/

> > article_1994.shtml

> > ======================

> >

> > Thanks to Tony for pointing out the Australian findings.

> >

> > Sue ,

> > Upstate New Yorark

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