Re: Common Variable Immune Deficiency

[Guest guest]

this line of thought is most interesting and my gut feeling is you are

on the RIGHT track

bleu

On 28 Jul 2005, at 15:16, Jim Kepner wrote:

> Sue-

> I've been looking into CVID as both my daughter and I

> have IG deficiencies, commonly found in CFS. Hers are

> across the board IGA/IGG/IGM, mine are IGG. Although

> most CFS doc's look at these as a result of immune

> depletion as a result of the disorder, the CVID can be

> tested for by a knowledgeable immunologist. It may be

> that a lot of us with these chronic infections have a

> primary immune deficiency, hence abx are palliative or

> preventative, but not curative. In that case, we would

> need regular IVIG supplement as we simply don't

> produce enough immunoglobulins to defend ourselves. We

> are consulting an immunologist for our daughter, we'll

> see what it brings.

> Jim

>

>

>

[Guest guest]

> >We

> are consulting an immunologist for our daughter, we'll

> see what it brings.

> Jim

==========

Hi Jim,

If I can find old notes from a visit to an immunologist I'll send them

to you back channel. This guy was one of the best doctors we've seen.

There wasn't much he could do for Selective IgA Deficiency, but you and

your daughter--with multiple deficiencies--have a better shot.

Sue ,

Upstate New York

[Guest guest]

> this line of thought is most interesting and my gut feeling is you

are

> on the RIGHT track

>

> bleu

Personally my view is opposite, just because of evolutionary

reasoning. I am convinced by the reasoning that most severe ailments

come from pathogens, because genes causing them should be eliminated.

Even most genetic diseases may exist because heterozygous carriage of

the offending allele confers protection against some important

pathogen - as is the case for sickle cell trait re malaria (and, some

say, the cystic fibrosis mutation re TB).

Obviously there is a genetic factor in eg MS where identical twins

are many many times more likely to suffer MS in common than are

fraternal twins. However this may not indicate a genetic immunity

defect in the common sense, but merely an " unfortunate hand of cards "

for resisting the specific set of wiles possesed by the (quasi-

putative) MS pathogen at this particular point in evolutionary time.

What makes one poor at resisting one pathogen may make one great at

resisting another.

> On 28 Jul 2005, at 15:16, Jim Kepner wrote:

>

> > Sue-

> > I've been looking into CVID as both my daughter and I

> > have IG deficiencies, commonly found in CFS. Hers are

> > across the board IGA/IGG/IGM, mine are IGG. Although

> > most CFS doc's look at these as a result of immune

> > depletion as a result of the disorder, the CVID can be

> > tested for by a knowledgeable immunologist. It may be

> > that a lot of us with these chronic infections have a

> > primary immune deficiency, hence abx are palliative or

> > preventative, but not curative. In that case, we would

> > need regular IVIG supplement as we simply don't

> > produce enough immunoglobulins to defend ourselves. We

> > are consulting an immunologist for our daughter, we'll

> > see what it brings.

> > Jim

> >

> >

> >

[Guest guest]

not going to argue, but i suspect many are open to some. still its

bacteria that have the upper hand.

On 28 Jul 2005, at 18:41, Hodologica wrote:

> What makes one poor at resisting one pathogen may make one great at

> resisting another.

[Guest guest]

ech this is really unclear

I meant, " I am convinced by the reasoning that most severe ailments

come from pathogens, because any genes that might cause severe illness

should be eliminated from the gene pool, and therefore disease should

be expected to come from factors outside the body. "

> I am convinced by the reasoning that most severe ailments

> come from pathogens, because genes causing them should be eliminated.