Re: BbCRASP-1 is a homodimer

July 5, 2005

Oops, think I lost that reply...anyway, was saying you are too cool

for finding this, which I could barely understand as i read it while

listening to X & Y the wonderful new coldplay album, but inspires me to

call, this week, a biophysicist I talked to a few years ago, and see

if he's willing to look at Bb He was slightly altering the arms of

taxol--and they were quantum length--and it was binding differently.

It never occurred to me to try to get at BB this way. My two

solutions thus far for killing the corkscrew were perhaps clever but

certainly not that complex.

> Ie, each copy is stuck to another like copy to form a single active

> unit.

>

>

> I think they are saying that a small drug blocking the dimerization

> would be an interesting lead - I am not sure exactly what they are

> getting at tho. Anyway if you can stop this system, Bb would not be

> resistant to serum anymore. It just might do the trick.

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