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<Jaep@L...> wrote:

....a deep colour denotes a robust Immune response...

Hi ,

I've had a sinus infection for the last month, doing a little better

now, but constantly hacking up greenish, brownish, even tinged

with purple, mucous. Does this mean my immune system is

actually beginning to act normally? I'd love to have a ROBUST

immune system!

d.

p.s. No fever except for the first 1-2 days...

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> Immunological down-regulation of host defences in fungal

infections.

>

> JW.

>

> Department of Microbiology and Immunology, University of

Oklahoma Health

> Sciences Center, Oklahoma City, USA. juneann-murphy@o...

>

> Fungal pathogens use multiple virulence factors to cause

progressive

> disease. A mechanism that could be regarded as a virulence

factor is the

> fungal pathogen's ability to evade or down-regulate host

protective

> mechanisms.

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> PMID: 10865902 [MEDLINE]

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> See also Medline 11098625, 11387665, 11437340

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> Mayo Clinic researchers have proposed that most chronic

sinus infections may

> be caused by an immune system response to fungi.

>

> * Article in Mayo

<http://www.mayo.edu/proceedings/1999/7409a1.pdf>

> Clinic Proceedings

>

>

> Many studies here at the Mayo Clinic have added evidence to

our thinking

> that chronic rhinosinusitis is caused by an immune reaction to

fungi in the

> nose. Our original study linking chronic rhinosinusitis to fungi

in the

> nose, which was published in the Mayo Clinic Proceedings in

September 1999,

> has been reproduced and confirmed by a sinus center in

Europe (ENT

> University Hospital in Graz, Austria).

>

> There are currently 16 studies at Mayo Clinic Rochester to

further

> investigate the role of fungi in inflammatory diseases of the

respiratory

> tract.

> In addition, researchers from the Allergic Diseases Research

Laboratory at

> the Mayo Clinic in Rochester found that certain white blood

cells

>

> called T-Lymphocytes are reacting to the fungi and were

producing the kind

> of inflammation we see in the sinuses, and that healthy people

did

>

> not react in that way. This work was presented at the 2001

Annual Meeting of

> the American Academy of Allergy, Asthma and Immunology

and

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> will be published soon.

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> The evidence was so convincing that the National Institute of

Health

> (NIH)has given Mayo Clinic a $2.5 million grant to further

investigate the

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> mechanisms behind this immunologic response to the fungi.

>

> If you have chronic sinusitis—that is, a sinus inflammation that

persists

> for three months or longer—we recommend that you see your

personal

> physician or an ear, nose and throat specialist

(otorhinolaryngologist) for

> the appropriate treatment for this disease. Many times the

disease is

> associated with asthma or allergies and treatment of those

associated

> problems tends to help the chronic sinusitis.

>

> Antibiotics don't help chronic sinusitis in the long run because

they target

> bacteria, which are not usually the cause of chronic sinusitis.

> Anti-histamines, nasal steroid sprays and systemic steroids

are the

> mainstays of treatment today, depending on the symptoms of

the patient.

>

> Over-the-counter medications, including salt-water nasal

washes and mist

> sprays, are useful in treating the symptoms of chronic

sinusitis, but do not

> eliminate the inflammation.

>

> Dept of Otorhinolaryngology

> Mayo Clinic

> Rochester, Minnesota

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> This latest report supports the link with CFS [ME] an

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> d fungal infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm

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> Stop press information

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http://www.sciencedaily.com/releases/2004/03/040324072619.h

tm

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> See Medline 12464951 for results of a study using antifungal

drugs to treat

> sinusitis.

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> [infections] info on sinus bacteria

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> I need info on a bacteria or fungus that starts in the sinus

area and

> later can be seen as bacterial tracks that run down the

outside of the

> cheeks. I seen a 1938 medical movie showing a person with

very clear

> tracks that ran down the outside of his cheeks. I know that

chlamydia

> bacteria can set up as cysts on the side of a persons head,

also at

> the base of the spine. could this bacteria be the cause of

these

> tracks, growing down the cheeks. anyone with info or

comments, I need

> to hear your thoughts. Jimd

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