Guest guest Posted July 6, 2005 Report Share Posted July 6, 2005 Dura, not certain... but check Vidals dense paper on STAT / IFN-g / 1,25d crosstalk, and , Jacques Lemire. Of course Jacques Lemire has written ~50 papers on vit D, but you may be able to discern from the titles which ones are reviews that would most likely lay out the workings systematically. I am pretty sure in health the conversion takes place only in the kidneys, tho I am not 100% sure. > > > " neither increased exposure to sunlight nor increased oral intake of > > > vitamin D raised blood concentrations of 1,25(OH)2D " (3 studies > > > cited) > > > > But - is that in healthy mammals or inflamed ones? The 25 --> 1,25 > > conversion is very different in inflamed states than what it is in > > health. > > > > > Furthermore, the author states: > > > > > > " as a person becomes vitamin D-deficient, there is an increase in the > > > concentration of parathyroid hormone (PTH), which increases the renal > > > production of 1,25(OH)2D, the circulating concentrations of which > > > often become normal or even elevated " > > > > Aha, very interesting. Quote Link to comment Share on other sites More sharing options...
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