Guest guest Posted July 23, 2005 Report Share Posted July 23, 2005 Jelly and others, I have been diagnosed by a Rheumatologist with Lupus & by an Infectious Disease Dr. with Lyme….extremely high titers of multiple bands on the Igenex test. The ID Dr. said it’s one of the worst Western Blot tests he’s ever seen. My Rheumatologists argue that all of the crazy antibodies I have could have cross reacted with the antigens causing a false positive. There could be something to this….there’s mention in the literature about it including on Igenex’ own web site. It’s frustrating to have 2 different specialists with two EXTREMELY different opinions as to what is wrong with you. My Rheumatologist is willing to let me play out the Lyme game as my ID Dr. has prescribed Diflucan and Green tea. See below for the synergistic effect of green tea on Diflucan. Obviously, it possesses other great qualities such as being a superb antioxidant, anti cancer, anti viral & anti bacterial. He prescribes Diflucan not b/c of the yeast angle but b/c of the P450 pathway angle, basically theorizing that the Diflucan starves out the Lyme nutrients. I’ve been on Diflucan since February and added the green tea 2 weeks ago. It’s dirt cheap & I get it off the web. The Diflucan initially made me very fatigued (more so than normal) but I’m stabilized as far as that goes now. Just thought you guys might find the green tea aspect interesting. BTW, my Infectious Dz. Dr. is not some strip mall Dr. He’s the chair of the dept. of a huge prestigious teaching hospital. He definitely thinks out of the box. He also added plain ol Penicillin per the Schart protocol, but did not want me to suspend the Diflucan. J Antimicrob Chemother. 2004 Feb;53(2):225-9. Epub 2003 Dec 19. Related Articles, Links Multiple effects of green tea catechin on the antifungal activity of antimycotics against Candida albicans. Hirasawa M, Takada K. Department of Microbiology, Nihon University School of Dentistry at Matsudo, 2-870-1 Sakaecho-nishi, Matsudo City, Chiba 271-8587, Japan. masahira@... OBJECTIVES: The susceptibility of Candida albicans to catechin under varying pH conditions and the synergism of the combination of catechin and antimycotics were evaluated.Method: Antifungal activity was determined by broth dilution and calculation of cfu. RESULTS: The antifungal activity of catechin was pH dependent. The concentration of epigallocatechin gallate (EGCg) causing 90% growth inhibition of tested strains of C. albicans was 2000 mg/L at pH 6.0, 500-1000 mg/L at pH 6.5 and 15.6-250 mg/L at pH 7.0. Among catechins, pyrogallol catechin showed stronger antifungal activity against C. albicans than catechol catechin. The addition of 6.25-25 or 3.12-12.5 mg/L EGCg to amphotericin B 0.125 or 0.25 mg/L (below MIC) at pH 7.0 resulted in enhancement, respectively, of the antifungal effect of amphotericin B against amphotericin B-susceptible or -resistant C. albicans. Combined treatment with 3.12-12.5 mg/L EGCg plus amphotericin B 0.5 mg/L (below MIC) markedly decreased the growth of amphotericin B-resistant C. albicans. When fluconazole-susceptible C. albicans was treated with 25-50 mg/L EGCg and fluconazole 0.125-0.25 mg/L (below MIC), its growth was inhibited by 93.0%-99.4% compared with its growth in the presence of fluconazole alone. The combined use of 12.5 mg/L EGCg and fluconazole 10-50 mg/L (below MIC) inhibited the growth of fluconazole-resistant C. albicans by 98.5%-99.7%. CONCLUSIONS: These results indicate that EGCg enhances the antifungal effect of amphotericin B or fluconazole against antimycotic-susceptible and -resistant C. albicans. Combined treatment with catechin allows the use of lower doses of antimycotics and induces multiple antifungal effects. It is hoped that this may help to avoid the side effects of antimycotics. PMID: 14688042 [PubMed - indexed for MEDLINE] From: infections [mailto:infections ] On Behalf Of jellybelly92008 Sent: Saturday, July 23, 2005 12:36 PM infections Subject: [infections] Re: info on sinus bacteria Well, here I am. Maybe I am the person with Lyme, taking an antifungal, Diflucan, that you are looking for. My LLMD put be on a two month coarse of Diflucan because a little over a year ago, I was put on the antifunal, Nizorel and seemed to make quite a bit of progress. So we thought it might be a good idea to try again. I've been on the Difulcan for about 2 weeks and feel rather cruddy. Brain not working, lethargic, achey, eyes burn, sweaty, I'm not having fun. Thing is, my doc also put me on a beta blocker to slow my heart down. During my flare it was up to 100. My heart has gone from the 100s to the mid 60s where it has never been. So I don't know if I feel cruddy because of the beta blocker, the Diflucan or the flair. I had actually thought I would take a break from the Diflucan to see if I feel any better. My LLMD is aware of the doctor who believes he is curing Lyme by treating with antifungals. We actually talked about it, and he is wondering if progress even in a Lyme patient isn't due to an underlying yeast infestation. So we are trying to cover all the bases, before we start with ABX if they are still needed. > > > > Hello, Chronic sinusitis is fungal based…..Fungi down > regulates > > > the immune > > > > system , in fact the latest drugs used to depress the IS in > > > transplant > > > > patients are fungal based… your bacterial infection is > > > incidental .The > > > > hallmark of the condition is white or clear mucus..[is it?] > … > > When > > > infected > > > > mucus is coloured by dead White blood cells , that is in a > > normal > > > common or > > > > garden bacterial infection, a deep colour denotes a robust > > Immune > > > response > > > > ..when infected with fungi our response is muted hence the > > lack of > > > colour , > > > > our IR is akikin to an allergic response to fungi …. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in fungal > > > infections. > > > > > > > > JW. > > > > > > > > Department of Microbiology and Immunology, University of > > Oklahoma > > > Health > > > > Sciences Center, Oklahoma City, USA. juneann- murphy@o... > > > > > > > > Fungal pathogens use multiple virulence factors to cause > > > progressive > > > > disease. A mechanism that could be regarded as a virulence > > factor > > > is the > > > > fungal pathogen's ability to evade or down-regulate host > > protective > > > > mechanisms. > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > sinus > > > infections may > > > > be caused by an immune system response to fungi. > > > > > > > > * Article in Mayo > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > Clinic Proceedings > > > > > > > > > > > > Many studies here at the Mayo Clinic have added evidence to > our > > > thinking > > > > that chronic rhinosinusitis is caused by an immune reaction > to > > > fungi in the > > > > nose. Our original study linking chronic rhinosinusitis to > > fungi > > > in the > > > > nose, which was published in the Mayo Clinic Proceedings in > > > September 1999, > > > > has been reproduced and confirmed by a sinus center in > Europe > > (ENT > > > > University Hospital in Graz, Austria). > > > > > > > > There are currently 16 studies at Mayo Clinic Rochester to > > further > > > > investigate the role of fungi in inflammatory diseases of > the > > > respiratory > > > > tract. > > > > In addition, researchers from the Allergic Diseases Research > > > Laboratory at > > > > the Mayo Clinic in Rochester found that certain white blood > > cells > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > producing > > > the kind > > > > of inflammation we see in the sinuses, and that healthy > people > > did > > > > > > > > not react in that way. This work was presented at the 2001 > > Annual > > > Meeting of > > > > the American Academy of Allergy, Asthma and Immunology and > > > > > > > > will be published soon. > > > > > > > > The evidence was so convincing that the National Institute > of > > > Health > > > > (NIH)has given Mayo Clinic a $2.5 million grant to further > > > investigate the > > > > > > > > mechanisms behind this immunologic response to the fungi. > > > > > > > > If you have chronic sinusitis—that is, a sinus inflammation > > that > > > persists > > > > for three months or longer—we recommend that you see your > > personal > > > > physician or an ear, nose and throat specialist > > > (otorhinolaryngologist) for > > > > the appropriate treatment for this disease. Many times the > > disease > > > is > > > > associated with asthma or allergies and treatment of those > > > associated > > > > problems tends to help the chronic sinusitis. > > > > > > > > Antibiotics don't help chronic sinusitis in the long run > > because > > > they target > > > > bacteria, which are not usually the cause of chronic > sinusitis. > > > > Anti-histamines, nasal steroid sprays and systemic steroids > > are the > > > > mainstays of treatment today, depending on the symptoms of > the > > > patient. > > > > > > > > Over-the-counter medications, including salt-water nasal > washes > > > and mist > > > > sprays, are useful in treating the symptoms of chronic > > sinusitis, > > > but do not > > > > eliminate the inflammation. > > > > > > > > Dept of Otorhinolaryngology > > > > Mayo Clinic > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > d fungal > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > Stop press information > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using antifungal > > drugs > > > to treat > > > > sinusitis. > > > > > > > > [infections] info on sinus > bacteria > > > > > > > > > > > > I need info on a bacteria or fungus that starts in the > sinus > > > area and > > > > later can be seen as bacterial tracks that run down the > > outside > > > of the > > > > cheeks. I seen a 1938 medical movie showing a person with > > very > > > clear > > > > tracks that ran down the outside of his cheeks. I know > that > > > chlamydia > > > > bacteria can set up as cysts on the side of a persons > head, > > also > > > at > > > > the base of the spine. could this bacteria be the cause > of > > these > > > > tracks, growing down the cheeks. anyone with info or > > comments, > > > I need > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 I was also dx with Lupus.. then when I just out-lived that dx- they went on to other autoimmune dx's... I know they say people with Lupus can test positive (FALSELY test positive) to Lupus - but I've never seen anything to back that statement up. They're spouting THEORY. There are several bands on a WB for Lyme that do not cross react with anything... and I just can't see people with lupus making antibodies out of the blue to specific proteins expressed only by Lyme bacteria. I don't buy what they're selling- never have. Barb > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > regulates > > > > the immune > > > > > system , in fact the latest drugs used to depress the > IS in > > > > transplant > > > > > patients are fungal based. your bacterial infection is > > > > incidental .The > > > > > hallmark of the condition is white or clear mucus.. [is > it?] > > . > > > When > > > > infected > > > > > mucus is coloured by dead White blood cells , that is > in a > > > normal > > > > common or > > > > > garden bacterial infection, a deep colour denotes a > robust > > > Immune > > > > response > > > > > ..when infected with fungi our response is muted hence > the > > > lack of > > > > colour , > > > > > our IR is akikin to an allergic response to fungi > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > fungal > > > > infections. > > > > > > > > > > JW. > > > > > > > > > > Department of Microbiology and Immunology, University > of > > > Oklahoma > > > > Health > > > > > Sciences Center, Oklahoma City, USA. juneann- > murphy@o... > > > > > > > > > > Fungal pathogens use multiple virulence factors to > cause > > > > progressive > > > > > disease. A mechanism that could be regarded as a > virulence > > > factor > > > > is the > > > > > fungal pathogen's ability to evade or down-regulate > host > > > protective > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > > sinus > > > > infections may > > > > > be caused by an immune system response to fungi. > > > > > > > > > > * Article in Mayo > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > Clinic Proceedings > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > evidence to > > our > > > > thinking > > > > > that chronic rhinosinusitis is caused by an immune > reaction > > to > > > > fungi in the > > > > > nose. Our original study linking chronic > rhinosinusitis to > > > fungi > > > > in the > > > > > nose, which was published in the Mayo Clinic > Proceedings in > > > > September 1999, > > > > > has been reproduced and confirmed by a sinus center in > > Europe > > > (ENT > > > > > University Hospital in Graz, Austria). > > > > > > > > > > There are currently 16 studies at Mayo Clinic > Rochester to > > > further > > > > > investigate the role of fungi in inflammatory diseases > of > > the > > > > respiratory > > > > > tract. > > > > > In addition, researchers from the Allergic Diseases > Research > > > > Laboratory at > > > > > the Mayo Clinic in Rochester found that certain white > blood > > > cells > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > > producing > > > > the kind > > > > > of inflammation we see in the sinuses, and that healthy > > people > > > did > > > > > > > > > > not react in that way. This work was presented at the > 2001 > > > Annual > > > > Meeting of > > > > > the American Academy of Allergy, Asthma and Immunology > and > > > > > > > > > > will be published soon. > > > > > > > > > > The evidence was so convincing that the National > Institute > > of > > > > Health > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > further > > > > investigate the > > > > > > > > > > mechanisms behind this immunologic response to the > fungi. > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > inflammation > > > that > > > > persists > > > > > for three months or longer-we recommend that you see > your > > > personal > > > > > physician or an ear, nose and throat specialist > > > > (otorhinolaryngologist) for > > > > > the appropriate treatment for this disease. Many times > the > > > disease > > > > is > > > > > associated with asthma or allergies and treatment of > those > > > > associated > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > run > > > because > > > > they target > > > > > bacteria, which are not usually the cause of chronic > > sinusitis. > > > > > Anti-histamines, nasal steroid sprays and systemic > steroids > > > are the > > > > > mainstays of treatment today, depending on the > symptoms of > > the > > > > patient. > > > > > > > > > > Over-the-counter medications, including salt-water > nasal > > washes > > > > and mist > > > > > sprays, are useful in treating the symptoms of chronic > > > sinusitis, > > > > but do not > > > > > eliminate the inflammation. > > > > > > > > > > Dept of Otorhinolaryngology > > > > > Mayo Clinic > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > d fungal > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > antifungal > > > drugs > > > > to treat > > > > > sinusitis. > > > > > > > > > > [infections] info on sinus > > bacteria > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > the > > sinus > > > > area and > > > > > later can be seen as bacterial tracks that run down > the > > > outside > > > > of the > > > > > cheeks. I seen a 1938 medical movie showing a > person with > > > very > > > > clear > > > > > tracks that ran down the outside of his cheeks. I > know > > that > > > > chlamydia > > > > > bacteria can set up as cysts on the side of a persons > > head, > > > also > > > > at > > > > > the base of the spine. could this bacteria be the > cause > > of > > > these > > > > > tracks, growing down the cheeks. anyone with info or > > > comments, > > > > I need > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 I’m saying people with lupus antibodies can falsely test positive to Lyme, not lupus. But, beside the point, even IGENEX’ web site states that people with certain rheumatic conditions including RA and lupus can end up false testing positive. I do understand that there are certain bands that have never shown any cross reactivity with anything, but I’m not convinced that they’ve done a lot of testing on patients with my certain specific set of antibodies. I don’t live in an endemic area for Lyme, never had a tick bite that I’m aware of, no rashes & nothing else red flag in my history for Lyme. I’m not saying that I don’t have it………..I really don’t know what to think. But more importantly, what’s worse; lupus or chronic Lyme? I’ve been on the AB protocol 2+ years without any improvement. It’s sort of like the joke of the Dr. saying “I have good news and bad news. The good news is you don’t have lupus & the bad news is you have chronic Lyme.” My approach is to treat the Lyme as suggested & hope that I can keep my discomfort to the point where I don’t need strong immunosuppressant drugs. There are sure a lot of days where I could benefit from about 10mg of Prednisone. I suffer through it though. From: infections [mailto:infections ] On Behalf Of Barb Peck Sent: Saturday, July 23, 2005 9:03 PM infections Subject: [infections] Re: Green tea inhances diflucan I was also dx with Lupus.. then when I just out-lived that dx- they went on to other autoimmune dx's... I know they say people with Lupus can test positive (FALSELY test positive) to Lupus - but I've never seen anything to back that statement up. They're spouting THEORY. There are several bands on a WB for Lyme that do not cross react with anything... and I just can't see people with lupus making antibodies out of the blue to specific proteins expressed only by Lyme bacteria. I don't buy what they're selling- never have. Barb > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > regulates > > > > the immune > > > > > system , in fact the latest drugs used to depress the > IS in > > > > transplant > > > > > patients are fungal based. your bacterial infection is > > > > incidental .The > > > > > hallmark of the condition is white or clear mucus.. [is > it?] > > . > > > When > > > > infected > > > > > mucus is coloured by dead White blood cells , that is > in a > > > normal > > > > common or > > > > > garden bacterial infection, a deep colour denotes a > robust > > > Immune > > > > response > > > > > ..when infected with fungi our response is muted hence > the > > > lack of > > > > colour , > > > > > our IR is akikin to an allergic response to fungi > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > fungal > > > > infections. > > > > > > > > > > JW. > > > > > > > > > > Department of Microbiology and Immunology, University > of > > > Oklahoma > > > > Health > > > > > Sciences Center, Oklahoma City, USA. juneann- > murphy@o... > > > > > > > > > > Fungal pathogens use multiple virulence factors to > cause > > > > progressive > > > > > disease. A mechanism that could be regarded as a > virulence > > > factor > > > > is the > > > > > fungal pathogen's ability to evade or down-regulate > host > > > protective > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > > sinus > > > > infections may > > > > > be caused by an immune system response to fungi. > > > > > > > > > > * Article in Mayo > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > Clinic Proceedings > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > evidence to > > our > > > > thinking > > > > > that chronic rhinosinusitis is caused by an immune > reaction > > to > > > > fungi in the > > > > > nose. Our original study linking chronic > rhinosinusitis to > > > fungi > > > > in the > > > > > nose, which was published in the Mayo Clinic > Proceedings in > > > > September 1999, > > > > > has been reproduced and confirmed by a sinus center in > > Europe > > > (ENT > > > > > University Hospital in Graz, Austria). > > > > > > > > > > There are currently 16 studies at Mayo Clinic > Rochester to > > > further > > > > > investigate the role of fungi in inflammatory diseases > of > > the > > > > respiratory > > > > > tract. > > > > > In addition, researchers from the Allergic Diseases > Research > > > > Laboratory at > > > > > the Mayo Clinic in Rochester found that certain white > blood > > > cells > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > > producing > > > > the kind > > > > > of inflammation we see in the sinuses, and that healthy > > people > > > did > > > > > > > > > > not react in that way. This work was presented at the > 2001 > > > Annual > > > > Meeting of > > > > > the American Academy of Allergy, Asthma and Immunology > and > > > > > > > > > > will be published soon. > > > > > > > > > > The evidence was so convincing that the National > Institute > > of > > > > Health > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > further > > > > investigate the > > > > > > > > > > mechanisms behind this immunologic response to the > fungi. > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > inflammation > > > that > > > > persists > > > > > for three months or longer-we recommend that you see > your > > > personal > > > > > physician or an ear, nose and throat specialist > > > > (otorhinolaryngologist) for > > > > > the appropriate treatment for this disease. Many times > the > > > disease > > > > is > > > > > associated with asthma or allergies and treatment of > those > > > > associated > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > run > > > because > > > > they target > > > > > bacteria, which are not usually the cause of chronic > > sinusitis. > > > > > Anti-histamines, nasal steroid sprays and systemic > steroids > > > are the > > > > > mainstays of treatment today, depending on the > symptoms of > > the > > > > patient. > > > > > > > > > > Over-the-counter medications, including salt-water > nasal > > washes > > > > and mist > > > > > sprays, are useful in treating the symptoms of chronic > > > sinusitis, > > > > but do not > > > > > eliminate the inflammation. > > > > > > > > > > Dept of Otorhinolaryngology > > > > > Mayo Clinic > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > d fungal > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > antifungal > > > drugs > > > > to treat > > > > > sinusitis. > > > > > > > > > > [infections] info on sinus > > bacteria > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > the > > sinus > > > > area and > > > > > later can be seen as bacterial tracks that run down > the > > > outside > > > > of the > > > > > cheeks. I seen a 1938 medical movie showing a > person with > > > very > > > > clear > > > > > tracks that ran down the outside of his cheeks. I > know > > that > > > > chlamydia > > > > > bacteria can set up as cysts on the side of a persons > > head, > > > also > > > > at > > > > > the base of the spine. could this bacteria be the > cause > > of > > > these > > > > > tracks, growing down the cheeks. anyone with info or > > > comments, > > > > I need > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 Lyme refers to an infection. Lupus refers to a condition. I hate diseases that simply refer to symptoms as if that sums it up. " You've got MS. " Thanx but what is causing the lesions? " You've got ulcerative colitis. " Thanx but what is causing the inflamed and ulcerated gut lining? There has to be an (or multiple) infectious or toxic triggers. Perhaps you should consider a few other factors: Gluten sensitivity. You can either get testing for celiac sensitivity genes (not just anti gliadin antibodies) or just go off ALL gluten which means mostly forget eating in restaurants and foregoing much prepared food as gluten can sneak in. Its not that hard. Re evaluate in 6 months. Takes a while to repair the gut. Look for other coinfections such as babesia, or fungi as mentioned on here. Look into IVIG. > > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > > regulates > > > > > the immune > > > > > > system , in fact the latest drugs used to depress the > > IS in > > > > > transplant > > > > > > patients are fungal based. your bacterial infection is > > > > > incidental .The > > > > > > hallmark of the condition is white or clear mucus.. > [is > > it?] > > > . > > > > When > > > > > infected > > > > > > mucus is coloured by dead White blood cells , that is > > in a > > > > normal > > > > > common or > > > > > > garden bacterial infection, a deep colour denotes a > > robust > > > > Immune > > > > > response > > > > > > ..when infected with fungi our response is muted > hence > > the > > > > lack of > > > > > colour , > > > > > > our IR is akikin to an allergic response to fungi > > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > > fungal > > > > > infections. > > > > > > > > > > > > JW. > > > > > > > > > > > > Department of Microbiology and Immunology, University > > of > > > > Oklahoma > > > > > Health > > > > > > Sciences Center, Oklahoma City, USA. juneann- > > murphy@o... > > > > > > > > > > > > Fungal pathogens use multiple virulence factors to > > cause > > > > > progressive > > > > > > disease. A mechanism that could be regarded as a > > virulence > > > > factor > > > > > is the > > > > > > fungal pathogen's ability to evade or down-regulate > > host > > > > protective > > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most > chronic > > > sinus > > > > > infections may > > > > > > be caused by an immune system response to fungi. > > > > > > > > > > > > * Article in Mayo > > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > > Clinic Proceedings > > > > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > > evidence to > > > our > > > > > thinking > > > > > > that chronic rhinosinusitis is caused by an immune > > reaction > > > to > > > > > fungi in the > > > > > > nose. Our original study linking chronic > > rhinosinusitis to > > > > fungi > > > > > in the > > > > > > nose, which was published in the Mayo Clinic > > Proceedings in > > > > > September 1999, > > > > > > has been reproduced and confirmed by a sinus center in > > > Europe > > > > (ENT > > > > > > University Hospital in Graz, Austria). > > > > > > > > > > > > There are currently 16 studies at Mayo Clinic > > Rochester to > > > > further > > > > > > investigate the role of fungi in inflammatory > diseases > > of > > > the > > > > > respiratory > > > > > > tract. > > > > > > In addition, researchers from the Allergic Diseases > > Research > > > > > Laboratory at > > > > > > the Mayo Clinic in Rochester found that certain white > > blood > > > > cells > > > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and > were > > > > producing > > > > > the kind > > > > > > of inflammation we see in the sinuses, and that > healthy > > > people > > > > did > > > > > > > > > > > > not react in that way. This work was presented at the > > 2001 > > > > Annual > > > > > Meeting of > > > > > > the American Academy of Allergy, Asthma and > Immunology > > and > > > > > > > > > > > > will be published soon. > > > > > > > > > > > > The evidence was so convincing that the National > > Institute > > > of > > > > > Health > > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > > further > > > > > investigate the > > > > > > > > > > > > mechanisms behind this immunologic response to the > > fungi. > > > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > > inflammation > > > > that > > > > > persists > > > > > > for three months or longer-we recommend that you see > > your > > > > personal > > > > > > physician or an ear, nose and throat specialist > > > > > (otorhinolaryngologist) for > > > > > > the appropriate treatment for this disease. Many > times > > the > > > > disease > > > > > is > > > > > > associated with asthma or allergies and treatment of > > those > > > > > associated > > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > > run > > > > because > > > > > they target > > > > > > bacteria, which are not usually the cause of chronic > > > sinusitis. > > > > > > Anti-histamines, nasal steroid sprays and systemic > > steroids > > > > are the > > > > > > mainstays of treatment today, depending on the > > symptoms of > > > the > > > > > patient. > > > > > > > > > > > > Over-the-counter medications, including salt-water > > nasal > > > washes > > > > > and mist > > > > > > sprays, are useful in treating the symptoms of chronic > > > > sinusitis, > > > > > but do not > > > > > > eliminate the inflammation. > > > > > > > > > > > > Dept of Otorhinolaryngology > > > > > > Mayo Clinic > > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > > > > > d fungal > > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > > antifungal > > > > drugs > > > > > to treat > > > > > > sinusitis. > > > > > > > > > > > > [infections] info on sinus > > > bacteria > > > > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > > the > > > sinus > > > > > area and > > > > > > later can be seen as bacterial tracks that run down > > the > > > > outside > > > > > of the > > > > > > cheeks. I seen a 1938 medical movie showing a > > person with > > > > very > > > > > clear > > > > > > tracks that ran down the outside of his cheeks. I > > know > > > that > > > > > chlamydia > > > > > > bacteria can set up as cysts on the side of a > persons > > > head, > > > > also > > > > > at > > > > > > the base of the spine. could this bacteria be the > > cause > > > of > > > > these > > > > > > tracks, growing down the cheeks. anyone with info > or > > > > comments, > > > > > I need > > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 Wow Patrice, thank you!! Let me see if I got this right. The negative effects (I guess it's herxing) of the Diflucan can be minimized by the Green Tea. This is because something (ECGc, I think, don't know what it is) makes the yeast more suseptable to the Diflucan, so you don't have to take so much. Is that sort of right??? I am taking 100 mgs. of Diflucan now. How much do you take and how much green tea are you drinking. I really don't want to stop the Diflucan, but I already feel so much better not taking it today. Although my brain still feels like scrambled eggs. > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > regulates > > > > the immune > > > > > system , in fact the latest drugs used to depress the > IS in > > > > transplant > > > > > patients are fungal based. your bacterial infection is > > > > incidental .The > > > > > hallmark of the condition is white or clear mucus.. [is > it?] > > . > > > When > > > > infected > > > > > mucus is coloured by dead White blood cells , that is > in a > > > normal > > > > common or > > > > > garden bacterial infection, a deep colour denotes a > robust > > > Immune > > > > response > > > > > ..when infected with fungi our response is muted hence > the > > > lack of > > > > colour , > > > > > our IR is akikin to an allergic response to fungi > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > fungal > > > > infections. > > > > > > > > > > JW. > > > > > > > > > > Department of Microbiology and Immunology, University > of > > > Oklahoma > > > > Health > > > > > Sciences Center, Oklahoma City, USA. juneann- > murphy@o... > > > > > > > > > > Fungal pathogens use multiple virulence factors to > cause > > > > progressive > > > > > disease. A mechanism that could be regarded as a > virulence > > > factor > > > > is the > > > > > fungal pathogen's ability to evade or down-regulate > host > > > protective > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > > sinus > > > > infections may > > > > > be caused by an immune system response to fungi. > > > > > > > > > > * Article in Mayo > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > Clinic Proceedings > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > evidence to > > our > > > > thinking > > > > > that chronic rhinosinusitis is caused by an immune > reaction > > to > > > > fungi in the > > > > > nose. Our original study linking chronic > rhinosinusitis to > > > fungi > > > > in the > > > > > nose, which was published in the Mayo Clinic > Proceedings in > > > > September 1999, > > > > > has been reproduced and confirmed by a sinus center in > > Europe > > > (ENT > > > > > University Hospital in Graz, Austria). > > > > > > > > > > There are currently 16 studies at Mayo Clinic > Rochester to > > > further > > > > > investigate the role of fungi in inflammatory diseases > of > > the > > > > respiratory > > > > > tract. > > > > > In addition, researchers from the Allergic Diseases > Research > > > > Laboratory at > > > > > the Mayo Clinic in Rochester found that certain white > blood > > > cells > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > > producing > > > > the kind > > > > > of inflammation we see in the sinuses, and that healthy > > people > > > did > > > > > > > > > > not react in that way. This work was presented at the > 2001 > > > Annual > > > > Meeting of > > > > > the American Academy of Allergy, Asthma and Immunology > and > > > > > > > > > > will be published soon. > > > > > > > > > > The evidence was so convincing that the National > Institute > > of > > > > Health > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > further > > > > investigate the > > > > > > > > > > mechanisms behind this immunologic response to the > fungi. > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > inflammation > > > that > > > > persists > > > > > for three months or longer-we recommend that you see > your > > > personal > > > > > physician or an ear, nose and throat specialist > > > > (otorhinolaryngologist) for > > > > > the appropriate treatment for this disease. Many times > the > > > disease > > > > is > > > > > associated with asthma or allergies and treatment of > those > > > > associated > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > run > > > because > > > > they target > > > > > bacteria, which are not usually the cause of chronic > > sinusitis. > > > > > Anti-histamines, nasal steroid sprays and systemic > steroids > > > are the > > > > > mainstays of treatment today, depending on the > symptoms of > > the > > > > patient. > > > > > > > > > > Over-the-counter medications, including salt-water > nasal > > washes > > > > and mist > > > > > sprays, are useful in treating the symptoms of chronic > > > sinusitis, > > > > but do not > > > > > eliminate the inflammation. > > > > > > > > > > Dept of Otorhinolaryngology > > > > > Mayo Clinic > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > d fungal > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > antifungal > > > drugs > > > > to treat > > > > > sinusitis. > > > > > > > > > > [infections] info on sinus > > bacteria > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > the > > sinus > > > > area and > > > > > later can be seen as bacterial tracks that run down > the > > > outside > > > > of the > > > > > cheeks. I seen a 1938 medical movie showing a > person with > > > very > > > > clear > > > > > tracks that ran down the outside of his cheeks. I > know > > that > > > > chlamydia > > > > > bacteria can set up as cysts on the side of a persons > > head, > > > also > > > > at > > > > > the base of the spine. could this bacteria be the > cause > > of > > > these > > > > > tracks, growing down the cheeks. anyone with info or > > > comments, > > > > I need > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 Oh Fudge! I posted this once already and it didn't make it through. Grrrrr. Thanks so much Patrice. Are you saying or does the info say that Green Tea has something in it that makes fungus more susceptable to Diflucan? That way you need less of the Diflucan to achieve the same effect? Less Diflucan means less negative side effects. Are these side effects, herxing? I take 100 mgs of Diflucan a day, how much do you take? Man my brain feels like scrambled eggs. > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > regulates > > > > the immune > > > > > system , in fact the latest drugs used to depress the > IS in > > > > transplant > > > > > patients are fungal based. your bacterial infection is > > > > incidental .The > > > > > hallmark of the condition is white or clear mucus.. [is > it?] > > . > > > When > > > > infected > > > > > mucus is coloured by dead White blood cells , that is > in a > > > normal > > > > common or > > > > > garden bacterial infection, a deep colour denotes a > robust > > > Immune > > > > response > > > > > ..when infected with fungi our response is muted hence > the > > > lack of > > > > colour , > > > > > our IR is akikin to an allergic response to fungi > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > fungal > > > > infections. > > > > > > > > > > JW. > > > > > > > > > > Department of Microbiology and Immunology, University > of > > > Oklahoma > > > > Health > > > > > Sciences Center, Oklahoma City, USA. juneann- > murphy@o... > > > > > > > > > > Fungal pathogens use multiple virulence factors to > cause > > > > progressive > > > > > disease. A mechanism that could be regarded as a > virulence > > > factor > > > > is the > > > > > fungal pathogen's ability to evade or down-regulate > host > > > protective > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > > sinus > > > > infections may > > > > > be caused by an immune system response to fungi. > > > > > > > > > > * Article in Mayo > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > Clinic Proceedings > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > evidence to > > our > > > > thinking > > > > > that chronic rhinosinusitis is caused by an immune > reaction > > to > > > > fungi in the > > > > > nose. Our original study linking chronic > rhinosinusitis to > > > fungi > > > > in the > > > > > nose, which was published in the Mayo Clinic > Proceedings in > > > > September 1999, > > > > > has been reproduced and confirmed by a sinus center in > > Europe > > > (ENT > > > > > University Hospital in Graz, Austria). > > > > > > > > > > There are currently 16 studies at Mayo Clinic > Rochester to > > > further > > > > > investigate the role of fungi in inflammatory diseases > of > > the > > > > respiratory > > > > > tract. > > > > > In addition, researchers from the Allergic Diseases > Research > > > > Laboratory at > > > > > the Mayo Clinic in Rochester found that certain white > blood > > > cells > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > > producing > > > > the kind > > > > > of inflammation we see in the sinuses, and that healthy > > people > > > did > > > > > > > > > > not react in that way. This work was presented at the > 2001 > > > Annual > > > > Meeting of > > > > > the American Academy of Allergy, Asthma and Immunology > and > > > > > > > > > > will be published soon. > > > > > > > > > > The evidence was so convincing that the National > Institute > > of > > > > Health > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > further > > > > investigate the > > > > > > > > > > mechanisms behind this immunologic response to the > fungi. > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > inflammation > > > that > > > > persists > > > > > for three months or longer-we recommend that you see > your > > > personal > > > > > physician or an ear, nose and throat specialist > > > > (otorhinolaryngologist) for > > > > > the appropriate treatment for this disease. Many times > the > > > disease > > > > is > > > > > associated with asthma or allergies and treatment of > those > > > > associated > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > run > > > because > > > > they target > > > > > bacteria, which are not usually the cause of chronic > > sinusitis. > > > > > Anti-histamines, nasal steroid sprays and systemic > steroids > > > are the > > > > > mainstays of treatment today, depending on the > symptoms of > > the > > > > patient. > > > > > > > > > > Over-the-counter medications, including salt-water > nasal > > washes > > > > and mist > > > > > sprays, are useful in treating the symptoms of chronic > > > sinusitis, > > > > but do not > > > > > eliminate the inflammation. > > > > > > > > > > Dept of Otorhinolaryngology > > > > > Mayo Clinic > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > d fungal > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > antifungal > > > drugs > > > > to treat > > > > > sinusitis. > > > > > > > > > > [infections] info on sinus > > bacteria > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > the > > sinus > > > > area and > > > > > later can be seen as bacterial tracks that run down > the > > > outside > > > > of the > > > > > cheeks. I seen a 1938 medical movie showing a > person with > > > very > > > > clear > > > > > tracks that ran down the outside of his cheeks. I > know > > that > > > > chlamydia > > > > > bacteria can set up as cysts on the side of a persons > > head, > > > also > > > > at > > > > > the base of the spine. could this bacteria be the > cause > > of > > > these > > > > > tracks, growing down the cheeks. anyone with info or > > > comments, > > > > I need > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 Jelly, in a nutshell, yes, the green tea enhances the killing of the candida. It does NOT enhance the toxicity of the drug which is very important, so yes, your reasoning that you may require less is a reasonable assumption. My ID Dr. takes this abstract a step further & reasons that if it potentiates the action on candida, then it logically could do the same for Lyme. However, my ID Dr. has really encouraged me to stick out the Diflucan at higher doses. I take 200mg a day all at once. He thinks this is one of the better shots I might have with the least toxicity. So many are worried about liver toxicity, but he has literally treated thousands of AIDS pt.’s with cryptococci and they are all on even higher doses of Diflucan daily for years & he has never had anyone develop liver toxicity. And these are pretty sick folks to start with. He is not concerned in the least with liver toxicity. He wouldn’t even order liver panel on me, but I got my Fam. Practice too & it’s weird, but my liver enzymes came back better than ever. I don’t think the Diflucan makes me feel sick. When you feel lousy most of the time, it’s sometimes hard to evaluate, but it’s kind of weird, I take the diflucan mid day & I sort of get a little kick (boost in energy) from it now. THis diflucan therapy may all turn out to be hog wash, but we need to give it a good time trial to know for sure with enough numbers of people taking it. Again, when evaluating therapies, evaluate risk vs. benefit. I feel very comfortable taking green tea and Diflucan. When he starts talking IV Rocephin, then I’m going to have to give it some good long thought. Patrice From: infections [mailto:infections ] On Behalf Of jellybelly92008 Sent: Saturday, July 23, 2005 10:22 PM infections Subject: [infections] Re: Green tea inhances diflucan Oh Fudge! I posted this once already and it didn't make it through. Grrrrr. Thanks so much Patrice. Are you saying or does the info say that Green Tea has something in it that makes fungus more susceptable to Diflucan? That way you need less of the Diflucan to achieve the same effect? Less Diflucan means less negative side effects. Are these side effects, herxing? I take 100 mgs of Diflucan a day, how much do you take? Man my brain feels like scrambled eggs. > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > regulates > > > > the immune > > > > > system , in fact the latest drugs used to depress the > IS in > > > > transplant > > > > > patients are fungal based. your bacterial infection is > > > > incidental .The > > > > > hallmark of the condition is white or clear mucus.. [is > it?] > > . > > > When > > > > infected > > > > > mucus is coloured by dead White blood cells , that is > in a > > > normal > > > > common or > > > > > garden bacterial infection, a deep colour denotes a > robust > > > Immune > > > > response > > > > > ..when infected with fungi our response is muted hence > the > > > lack of > > > > colour , > > > > > our IR is akikin to an allergic response to fungi > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > fungal > > > > infections. > > > > > > > > > > JW. > > > > > > > > > > Department of Microbiology and Immunology, University > of > > > Oklahoma > > > > Health > > > > > Sciences Center, Oklahoma City, USA. juneann- > murphy@o... > > > > > > > > > > Fungal pathogens use multiple virulence factors to > cause > > > > progressive > > > > > disease. A mechanism that could be regarded as a > virulence > > > factor > > > > is the > > > > > fungal pathogen's ability to evade or down-regulate > host > > > protective > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > > sinus > > > > infections may > > > > > be caused by an immune system response to fungi. > > > > > > > > > > * Article in Mayo > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > Clinic Proceedings > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > evidence to > > our > > > > thinking > > > > > that chronic rhinosinusitis is caused by an immune > reaction > > to > > > > fungi in the > > > > > nose. Our original study linking chronic > rhinosinusitis to > > > fungi > > > > in the > > > > > nose, which was published in the Mayo Clinic > Proceedings in > > > > September 1999, > > > > > has been reproduced and confirmed by a sinus center in > > Europe > > > (ENT > > > > > University Hospital in Graz, Austria). > > > > > > > > > > There are currently 16 studies at Mayo Clinic > Rochester to > > > further > > > > > investigate the role of fungi in inflammatory diseases > of > > the > > > > respiratory > > > > > tract. > > > > > In addition, researchers from the Allergic Diseases > Research > > > > Laboratory at > > > > > the Mayo Clinic in Rochester found that certain white > blood > > > cells > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > > producing > > > > the kind > > > > > of inflammation we see in the sinuses, and that healthy > > people > > > did > > > > > > > > > > not react in that way. This work was presented at the > 2001 > > > Annual > > > > Meeting of > > > > > the American Academy of Allergy, Asthma and Immunology > and > > > > > > > > > > will be published soon. > > > > > > > > > > The evidence was so convincing that the National > Institute > > of > > > > Health > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > further > > > > investigate the > > > > > > > > > > mechanisms behind this immunologic response to the > fungi. > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > inflammation > > > that > > > > persists > > > > > for three months or longer-we recommend that you see > your > > > personal > > > > > physician or an ear, nose and throat specialist > > > > (otorhinolaryngologist) for > > > > > the appropriate treatment for this disease. Many times > the > > > disease > > > > is > > > > > associated with asthma or allergies and treatment of > those > > > > associated > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > run > > > because > > > > they target > > > > > bacteria, which are not usually the cause of chronic > > sinusitis. > > > > > Anti-histamines, nasal steroid sprays and systemic > steroids > > > are the > > > > > mainstays of treatment today, depending on the > symptoms of > > the > > > > patient. > > > > > > > > > > Over-the-counter medications, including salt-water > nasal > > washes > > > > and mist > > > > > sprays, are useful in treating the symptoms of chronic > > > sinusitis, > > > > but do not > > > > > eliminate the inflammation. > > > > > > > > > > Dept of Otorhinolaryngology > > > > > Mayo Clinic > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > d fungal > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > antifungal > > > drugs > > > > to treat > > > > > sinusitis. > > > > > > > > > > [infections] info on sinus > > bacteria > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > the > > sinus > > > > area and > > > > > later can be seen as bacterial tracks that run down > the > > > outside > > > > of the > > > > > cheeks. I seen a 1938 medical movie showing a > person with > > > very > > > > clear > > > > > tracks that ran down the outside of his cheeks. I > know > > that > > > > chlamydia > > > > > bacteria can set up as cysts on the side of a persons > > head, > > > also > > > > at > > > > > the base of the spine. could this bacteria be the > cause > > of > > > these > > > > > tracks, growing down the cheeks. anyone with info or > > > comments, > > > > I need > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 I take green tea caps. I get mine off of iherb.com & you want to look for the maximum ECGC (I think) that you can get in a cap for the price. I’m taking 500mg twice a day. In theory, your assumption that you would require less Diflucan is correct. However, I think if you want a shot at starving out the Lyme nutrients (which it is THEORIZED Diflucan does), you need to take a pretty hefty dose of Diflucan. I take 200mg daily without ill effects. THe green tea is supposed to boost this even further. It’s all THEORY, but my ID Dr. and I think very much alike in risk vs. benefit. Everyone would benefit from green tea…superb antioxidant, good for cardiovascular health, anti viral & antibacterial & now appears according to this abstract that it potentiates anti fungal activity of anti fungals. I could be wrong but I seriously doubt your “fried brain” is due to Diflucan. It’s extremely well tolerated by a group of individuals with AIDS who are a lot sicker than we are. It really has a very good safety profile despite it’s reputation. To add further fuel to the fire, I also take Placquenil with it. I figure I’m going to go at this all guns loaded. From: infections [mailto:infections ] On Behalf Of jellybelly92008 Sent: Saturday, July 23, 2005 10:03 PM infections Subject: [infections] Re: Green tea inhances diflucan Wow Patrice, thank you!! Let me see if I got this right. The negative effects (I guess it's herxing) of the Diflucan can be minimized by the Green Tea. This is because something (ECGc, I think, don't know what it is) makes the yeast more suseptable to the Diflucan, so you don't have to take so much. Is that sort of right??? I am taking 100 mgs. of Diflucan now. How much do you take and how much green tea are you drinking. I really don't want to stop the Diflucan, but I already feel so much better not taking it today. Although my brain still feels like scrambled eggs. > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > regulates > > > > the immune > > > > > system , in fact the latest drugs used to depress the > IS in > > > > transplant > > > > > patients are fungal based. your bacterial infection is > > > > incidental .The > > > > > hallmark of the condition is white or clear mucus.. [is > it?] > > . > > > When > > > > infected > > > > > mucus is coloured by dead White blood cells , that is > in a > > > normal > > > > common or > > > > > garden bacterial infection, a deep colour denotes a > robust > > > Immune > > > > response > > > > > ..when infected with fungi our response is muted hence > the > > > lack of > > > > colour , > > > > > our IR is akikin to an allergic response to fungi > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > fungal > > > > infections. > > > > > > > > > > JW. > > > > > > > > > > Department of Microbiology and Immunology, University > of > > > Oklahoma > > > > Health > > > > > Sciences Center, Oklahoma City, USA. juneann- > murphy@o... > > > > > > > > > > Fungal pathogens use multiple virulence factors to > cause > > > > progressive > > > > > disease. A mechanism that could be regarded as a > virulence > > > factor > > > > is the > > > > > fungal pathogen's ability to evade or down-regulate > host > > > protective > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most chronic > > sinus > > > > infections may > > > > > be caused by an immune system response to fungi. > > > > > > > > > > * Article in Mayo > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > Clinic Proceedings > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > evidence to > > our > > > > thinking > > > > > that chronic rhinosinusitis is caused by an immune > reaction > > to > > > > fungi in the > > > > > nose. Our original study linking chronic > rhinosinusitis to > > > fungi > > > > in the > > > > > nose, which was published in the Mayo Clinic > Proceedings in > > > > September 1999, > > > > > has been reproduced and confirmed by a sinus center in > > Europe > > > (ENT > > > > > University Hospital in Graz, Austria). > > > > > > > > > > There are currently 16 studies at Mayo Clinic > Rochester to > > > further > > > > > investigate the role of fungi in inflammatory diseases > of > > the > > > > respiratory > > > > > tract. > > > > > In addition, researchers from the Allergic Diseases > Research > > > > Laboratory at > > > > > the Mayo Clinic in Rochester found that certain white > blood > > > cells > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and were > > > producing > > > > the kind > > > > > of inflammation we see in the sinuses, and that healthy > > people > > > did > > > > > > > > > > not react in that way. This work was presented at the > 2001 > > > Annual > > > > Meeting of > > > > > the American Academy of Allergy, Asthma and Immunology > and > > > > > > > > > > will be published soon. > > > > > > > > > > The evidence was so convincing that the National > Institute > > of > > > > Health > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > further > > > > investigate the > > > > > > > > > > mechanisms behind this immunologic response to the > fungi. > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > inflammation > > > that > > > > persists > > > > > for three months or longer-we recommend that you see > your > > > personal > > > > > physician or an ear, nose and throat specialist > > > > (otorhinolaryngologist) for > > > > > the appropriate treatment for this disease. Many times > the > > > disease > > > > is > > > > > associated with asthma or allergies and treatment of > those > > > > associated > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > run > > > because > > > > they target > > > > > bacteria, which are not usually the cause of chronic > > sinusitis. > > > > > Anti-histamines, nasal steroid sprays and systemic > steroids > > > are the > > > > > mainstays of treatment today, depending on the > symptoms of > > the > > > > patient. > > > > > > > > > > Over-the-counter medications, including salt-water > nasal > > washes > > > > and mist > > > > > sprays, are useful in treating the symptoms of chronic > > > sinusitis, > > > > but do not > > > > > eliminate the inflammation. > > > > > > > > > > Dept of Otorhinolaryngology > > > > > Mayo Clinic > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > d fungal > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > antifungal > > > drugs > > > > to treat > > > > > sinusitis. > > > > > > > > > > [infections] info on sinus > > bacteria > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > the > > sinus > > > > area and > > > > > later can be seen as bacterial tracks that run down > the > > > outside > > > > of the > > > > > cheeks. I seen a 1938 medical movie showing a > person with > > > very > > > > clear > > > > > tracks that ran down the outside of his cheeks. I > know > > that > > > > chlamydia > > > > > bacteria can set up as cysts on the side of a persons > > head, > > > also > > > > at > > > > > the base of the spine. could this bacteria be the > cause > > of > > > these > > > > > tracks, growing down the cheeks. anyone with info or > > > comments, > > > > I need > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 Patrice, I'm pretty sure Barb just mis-typed, and meant to say that the specificity of certain bands for LYME is really uncontested - we have no contrary data, no explanation for how a Lupus diagnosis, or any other rheumatic condition, would produce antibodies to those specific antigen bands. Of course, having Lyme and knowing that all your symptoms are due to Lyme is something else. How far back do your symptoms go, in relation to the date of that Lyme test? A WB that strong might be described by some observers as more typical of early infection - that doesn't prove anything, I haven't seen any data that make that more than a 'tendency', and I suspect there are multiple variables involved in when and how the Immune System kicks out antibodies. But if you were symptomatic for several years before the test...and came back with those really high antibody titers...well, its just interesting to think about that. I'm kind of curious, too, which Lyme abx regimens you tried. There was no evidence of anything at all but continued deterioration when I was on oral antibiotics. No reason to believe that this treatment was even really scratching the surface. That changed with different abx and modes of administration... Are they doing something more for Lupus these days than steroids? Those are all just ' ruminates and tries to think about what he knows' questions...the only one that carries much weight with me is whether with the Fluconazole regimen you're going to get the relief you've been pursuing unsuccessfully. I hope you do! But if that turns out to disappoint, or leaves you with only partial improvements...and you've only tried oral antibiotic remedies...maybe it's worth thinking about taking the next step, see if a few months of IM Bicillin generates more of a response, or one of the IV drugs? I apologize in advance if you've addressed all these questions before. Like I said, feel free to ignore any and all of them. S. > > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > > regulates > > > > > the immune > > > > > > system , in fact the latest drugs used to depress the > > IS in > > > > > transplant > > > > > > patients are fungal based. your bacterial infection is > > > > > incidental .The > > > > > > hallmark of the condition is white or clear mucus.. > [is > > it?] > > > . > > > > When > > > > > infected > > > > > > mucus is coloured by dead White blood cells , that is > > in a > > > > normal > > > > > common or > > > > > > garden bacterial infection, a deep colour denotes a > > robust > > > > Immune > > > > > response > > > > > > ..when infected with fungi our response is muted > hence > > the > > > > lack of > > > > > colour , > > > > > > our IR is akikin to an allergic response to fungi > > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > > fungal > > > > > infections. > > > > > > > > > > > > JW. > > > > > > > > > > > > Department of Microbiology and Immunology, University > > of > > > > Oklahoma > > > > > Health > > > > > > Sciences Center, Oklahoma City, USA. juneann- > > murphy@o... > > > > > > > > > > > > Fungal pathogens use multiple virulence factors to > > cause > > > > > progressive > > > > > > disease. A mechanism that could be regarded as a > > virulence > > > > factor > > > > > is the > > > > > > fungal pathogen's ability to evade or down- regulate > > host > > > > protective > > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most > chronic > > > sinus > > > > > infections may > > > > > > be caused by an immune system response to fungi. > > > > > > > > > > > > * Article in Mayo > > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > > Clinic Proceedings > > > > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > > evidence to > > > our > > > > > thinking > > > > > > that chronic rhinosinusitis is caused by an immune > > reaction > > > to > > > > > fungi in the > > > > > > nose. Our original study linking chronic > > rhinosinusitis to > > > > fungi > > > > > in the > > > > > > nose, which was published in the Mayo Clinic > > Proceedings in > > > > > September 1999, > > > > > > has been reproduced and confirmed by a sinus center in > > > Europe > > > > (ENT > > > > > > University Hospital in Graz, Austria). > > > > > > > > > > > > There are currently 16 studies at Mayo Clinic > > Rochester to > > > > further > > > > > > investigate the role of fungi in inflammatory > diseases > > of > > > the > > > > > respiratory > > > > > > tract. > > > > > > In addition, researchers from the Allergic Diseases > > Research > > > > > Laboratory at > > > > > > the Mayo Clinic in Rochester found that certain white > > blood > > > > cells > > > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and > were > > > > producing > > > > > the kind > > > > > > of inflammation we see in the sinuses, and that > healthy > > > people > > > > did > > > > > > > > > > > > not react in that way. This work was presented at the > > 2001 > > > > Annual > > > > > Meeting of > > > > > > the American Academy of Allergy, Asthma and > Immunology > > and > > > > > > > > > > > > will be published soon. > > > > > > > > > > > > The evidence was so convincing that the National > > Institute > > > of > > > > > Health > > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > > further > > > > > investigate the > > > > > > > > > > > > mechanisms behind this immunologic response to the > > fungi. > > > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > > inflammation > > > > that > > > > > persists > > > > > > for three months or longer-we recommend that you see > > your > > > > personal > > > > > > physician or an ear, nose and throat specialist > > > > > (otorhinolaryngologist) for > > > > > > the appropriate treatment for this disease. Many > times > > the > > > > disease > > > > > is > > > > > > associated with asthma or allergies and treatment of > > those > > > > > associated > > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > > run > > > > because > > > > > they target > > > > > > bacteria, which are not usually the cause of chronic > > > sinusitis. > > > > > > Anti-histamines, nasal steroid sprays and systemic > > steroids > > > > are the > > > > > > mainstays of treatment today, depending on the > > symptoms of > > > the > > > > > patient. > > > > > > > > > > > > Over-the-counter medications, including salt-water > > nasal > > > washes > > > > > and mist > > > > > > sprays, are useful in treating the symptoms of chronic > > > > sinusitis, > > > > > but do not > > > > > > eliminate the inflammation. > > > > > > > > > > > > Dept of Otorhinolaryngology > > > > > > Mayo Clinic > > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > > > > > d fungal > > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > > antifungal > > > > drugs > > > > > to treat > > > > > > sinusitis. > > > > > > > > > > > > [infections] info on sinus > > > bacteria > > > > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > > the > > > sinus > > > > > area and > > > > > > later can be seen as bacterial tracks that run down > > the > > > > outside > > > > > of the > > > > > > cheeks. I seen a 1938 medical movie showing a > > person with > > > > very > > > > > clear > > > > > > tracks that ran down the outside of his cheeks. I > > know > > > that > > > > > chlamydia > > > > > > bacteria can set up as cysts on the side of a > persons > > > head, > > > > also > > > > > at > > > > > > the base of the spine. could this bacteria be the > > cause > > > of > > > > these > > > > > > tracks, growing down the cheeks. anyone with info > or > > > > comments, > > > > > I need > > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 24, 2005 Report Share Posted July 24, 2005 No , I appreciate your feedback. I think it was a typo that Barb typed. I don’t think we have enough data on patients with “true” rheumatic conditions and Western Blot tests to know what antibodies might cross react w/some of the WB bands. We do know that some with very high Rheumatoid Factors and high ANA’s do produce extremely positive WB tests. I guess it could be argued that these folks have a + RF and ANA due to Lyme, but there’s not much in the literature to support that either. The fact of the matter is, it hasn’t really been studied enough. They need to do Western Blots on a large group of participants with known high ANA titers or known high RF titers & churn out the data. The overwhelming feeling of fatigue goes back about 10 years. Sun sensitivity (no dermatologist knew what it was, but I believe it was some sort of discoid lupus) for 15 years +. Woke up one day in Sept 2001 UNABLE TO MOVE. Had NEVER had any sort of joint pain, this was out of the blue. Couldn’t dress myself, or even get out of bed for that matter. Went down the lupus route. The arsenals these days are still Prednisone, Placquenil (which I believe has been a TREMENDOUS help), and then they start getting into bigger guns such as Methotrexate, Cellcept (which interestingly is pretty well tolerated & effective), Cytoxan, etc. Not to imply Prednisone isn’t a big gun….it’s probably the worst of them all. Infec. Diz. Dr. started me on Minocin 100mg 2X daily. No appreciable improvement at all. Note, I have always stayed on the placquenil & have NO intention of ever stopping it. I also did a stint with oral Biaxin. Now I’m on good ol Penicillin/Diflucan/Green tea caps. Interestingly, my Western Blot was much more strikingly positive on the IGM side. Suggestive of long standing ACTIVE disease, since I know I’ve had it at least 4 years. Probably more. Genetics plays into this also. I have some very abnormal genetic clotting factors that my ID Dr. said made me “fertile ground” for my immune system not being able to clear this. I have done the heparin trick in the past w/no appreciable improvement. I probably wasn’t taking enough AB’s at the time. ID Dr. remarks I don’t seem as “sick” as his other Lyme patients. I think I could argue otherwise, when you have young children, you will yourself to put one foot in front of the other. But, I actually think the placquenil has helped me function a great deal better than I would’ve otherwise. Also of interest, I don’t seem to have sx. of neuro lyme. My loved ones might argue otherwise, but I seem to have dodged that bullet so far. All of my spelling errors & typos are only b/c I’m a lousy typist and/or speller. I crunch numbers all day long as a statistician & seem to handle this task without effort. I hope it stays that way, although every time I can’t find my keys, I get a little scared. I have thus far resisted the big arsenals the Rheumatologists have offered (except for large doses of Prednisone when I 1st got sick), but when I look around me & see patients with RA or lupus living pretty livable lives on Enbrel or Cellcept, I have to question if I’m doing myself any favors by not pursuing this route. My daughter’s teacher had juvenile RA, she has some long term damage from it. Enbrel has literally turned around her life. She has so much energy, she’s bouncing off the walls. PLEASE, spare the lectures on the long term side effects of Enbrel. I fully understand them. We are so full of inflammation……..that is definitely something the rheumatic and Lyme patients have in common. Simmering down the inflammatory side of things is very appealing to me. It’s tough to do without heavy duty drugs though. I do agree with the Marshall Protocol on some benefits of ARB’s or AI’s (at therapeutic doses)………that is proving fruitful. They’re also investigating the use of phosophodiesterase inhibitors which look promising. I really wish I did know more about the cross reactivity of antibodies with Western Blot testing for Lyme. I think there’s a lot we don’t know though. Patrice From: infections [mailto:infections ] On Behalf Of Schaafsma Sent: Saturday, July 23, 2005 11:12 PM infections Subject: [infections] Re: Green tea inhances diflucan Patrice, I'm pretty sure Barb just mis-typed, and meant to say that the specificity of certain bands for LYME is really uncontested - we have no contrary data, no explanation for how a Lupus diagnosis, or any other rheumatic condition, would produce antibodies to those specific antigen bands. Of course, having Lyme and knowing that all your symptoms are due to Lyme is something else. How far back do your symptoms go, in relation to the date of that Lyme test? A WB that strong might be described by some observers as more typical of early infection - that doesn't prove anything, I haven't seen any data that make that more than a 'tendency', and I suspect there are multiple variables involved in when and how the Immune System kicks out antibodies. But if you were symptomatic for several years before the test...and came back with those really high antibody titers...well, its just interesting to think about that. I'm kind of curious, too, which Lyme abx regimens you tried. There was no evidence of anything at all but continued deterioration when I was on oral antibiotics. No reason to believe that this treatment was even really scratching the surface. That changed with different abx and modes of administration... Are they doing something more for Lupus these days than steroids? Those are all just ' ruminates and tries to think about what he knows' questions...the only one that carries much weight with me is whether with the Fluconazole regimen you're going to get the relief you've been pursuing unsuccessfully. I hope you do! But if that turns out to disappoint, or leaves you with only partial improvements...and you've only tried oral antibiotic remedies...maybe it's worth thinking about taking the next step, see if a few months of IM Bicillin generates more of a response, or one of the IV drugs? I apologize in advance if you've addressed all these questions before. Like I said, feel free to ignore any and all of them. S. > > > > > > Hello, Chronic sinusitis is fungal based...Fungi down > > > regulates > > > > > the immune > > > > > > system , in fact the latest drugs used to depress the > > IS in > > > > > transplant > > > > > > patients are fungal based. your bacterial infection is > > > > > incidental .The > > > > > > hallmark of the condition is white or clear mucus.. > [is > > it?] > > > . > > > > When > > > > > infected > > > > > > mucus is coloured by dead White blood cells , that is > > in a > > > > normal > > > > > common or > > > > > > garden bacterial infection, a deep colour denotes a > > robust > > > > Immune > > > > > response > > > > > > ..when infected with fungi our response is muted > hence > > the > > > > lack of > > > > > colour , > > > > > > our IR is akikin to an allergic response to fungi > > .. > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Immunological down-regulation of host defences in > > fungal > > > > > infections. > > > > > > > > > > > > JW. > > > > > > > > > > > > Department of Microbiology and Immunology, University > > of > > > > Oklahoma > > > > > Health > > > > > > Sciences Center, Oklahoma City, USA. juneann- > > murphy@o... > > > > > > > > > > > > Fungal pathogens use multiple virulence factors to > > cause > > > > > progressive > > > > > > disease. A mechanism that could be regarded as a > > virulence > > > > factor > > > > > is the > > > > > > fungal pathogen's ability to evade or down- regulate > > host > > > > protective > > > > > > mechanisms. > > > > > > > > > > > > > > > > > > > > > > > > PMID: 10865902 [MEDLINE] > > > > > > > > > > > > See also Medline 11098625, 11387665, 11437340 > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Mayo Clinic researchers have proposed that most > chronic > > > sinus > > > > > infections may > > > > > > be caused by an immune system response to fungi. > > > > > > > > > > > > * Article in Mayo > > > > > <http://www.mayo.edu/proceedings/1999/7409a1.pdf> > > > > > > Clinic Proceedings > > > > > > > > > > > > > > > > > > Many studies here at the Mayo Clinic have added > > evidence to > > > our > > > > > thinking > > > > > > that chronic rhinosinusitis is caused by an immune > > reaction > > > to > > > > > fungi in the > > > > > > nose. Our original study linking chronic > > rhinosinusitis to > > > > fungi > > > > > in the > > > > > > nose, which was published in the Mayo Clinic > > Proceedings in > > > > > September 1999, > > > > > > has been reproduced and confirmed by a sinus center in > > > Europe > > > > (ENT > > > > > > University Hospital in Graz, Austria). > > > > > > > > > > > > There are currently 16 studies at Mayo Clinic > > Rochester to > > > > further > > > > > > investigate the role of fungi in inflammatory > diseases > > of > > > the > > > > > respiratory > > > > > > tract. > > > > > > In addition, researchers from the Allergic Diseases > > Research > > > > > Laboratory at > > > > > > the Mayo Clinic in Rochester found that certain white > > blood > > > > cells > > > > > > > > > > > > called T-Lymphocytes are reacting to the fungi and > were > > > > producing > > > > > the kind > > > > > > of inflammation we see in the sinuses, and that > healthy > > > people > > > > did > > > > > > > > > > > > not react in that way. This work was presented at the > > 2001 > > > > Annual > > > > > Meeting of > > > > > > the American Academy of Allergy, Asthma and > Immunology > > and > > > > > > > > > > > > will be published soon. > > > > > > > > > > > > The evidence was so convincing that the National > > Institute > > > of > > > > > Health > > > > > > (NIH)has given Mayo Clinic a $2.5 million grant to > > further > > > > > investigate the > > > > > > > > > > > > mechanisms behind this immunologic response to the > > fungi. > > > > > > > > > > > > If you have chronic sinusitis-that is, a sinus > > inflammation > > > > that > > > > > persists > > > > > > for three months or longer-we recommend that you see > > your > > > > personal > > > > > > physician or an ear, nose and throat specialist > > > > > (otorhinolaryngologist) for > > > > > > the appropriate treatment for this disease. Many > times > > the > > > > disease > > > > > is > > > > > > associated with asthma or allergies and treatment of > > those > > > > > associated > > > > > > problems tends to help the chronic sinusitis. > > > > > > > > > > > > Antibiotics don't help chronic sinusitis in the long > > run > > > > because > > > > > they target > > > > > > bacteria, which are not usually the cause of chronic > > > sinusitis. > > > > > > Anti-histamines, nasal steroid sprays and systemic > > steroids > > > > are the > > > > > > mainstays of treatment today, depending on the > > symptoms of > > > the > > > > > patient. > > > > > > > > > > > > Over-the-counter medications, including salt-water > > nasal > > > washes > > > > > and mist > > > > > > sprays, are useful in treating the symptoms of chronic > > > > sinusitis, > > > > > but do not > > > > > > eliminate the inflammation. > > > > > > > > > > > > Dept of Otorhinolaryngology > > > > > > Mayo Clinic > > > > > > Rochester, Minnesota > > > > > > > > > > > > > > > > > > > > > > > > This latest report supports the link with CFS [ME] an > > > > > > > > > > > > > > > > > > > > > > > > d fungal > > > infectionhttp://news.bbc.co.uk/1/hi/health/3141773.stm > > > > > > > > > > > > > > > > > > > > > > > > Stop press information > > > > > > > > > http://www.sciencedaily.com/releases/2004/03/040324072619.htm > > > > > > > > > > > > > > > > > > > > > > > > See Medline 12464951 for results of a study using > > antifungal > > > > drugs > > > > > to treat > > > > > > sinusitis. > > > > > > > > > > > > [infections] info on sinus > > > bacteria > > > > > > > > > > > > > > > > > > I need info on a bacteria or fungus that starts in > > the > > > sinus > > > > > area and > > > > > > later can be seen as bacterial tracks that run down > > the > > > > outside > > > > > of the > > > > > > cheeks. I seen a 1938 medical movie showing a > > person with > > > > very > > > > > clear > > > > > > tracks that ran down the outside of his cheeks. I > > know > > > that > > > > > chlamydia > > > > > > bacteria can set up as cysts on the side of a > persons > > > head, > > > > also > > > > > at > > > > > > the base of the spine. could this bacteria be the > > cause > > > of > > > > these > > > > > > tracks, growing down the cheeks. anyone with info > or > > > > comments, > > > > > I need > > > > > > to hear your thoughts. Jimd > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
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