More about body temp responses to infection

[Guest guest]

I've been able to read a bit the last couple days. I stumbled on to

some interesting things about the relationship between endotoxin and

body temperature.

In this literature, elevated body temp is referred to as

hyperthermia, depressed body temperature is referred to as

hypothermia, and endotoxemia refers to illness due to circulating

endotoxins.

The first interesting thing I read was that endotoxemia can case

BOTH hypothermia and hyperthermia.

The second was that hypothermia is protective against the harmful

effects of endotoxemia.

The third was that hypothermia apparently induces the production of

anti-inflammatory cytokines like IL10, that help limit or moderate

the inflammatory cascade which endotoxemia initiates. Here's a link

to one full-text paper on the subject:

http://www.chestjournal.org/cgi/content/full/125/4/1483

Is it too big a jump to ask if the sustained reduction in body

temperature noted so many Lyme patients report might in fact be a

response to endotoxemia?

I wonder what others think.