Re: More about body temp...correction

[Guest guest]

I wrote: " The second was that hypothermia is protective against the

harmful effects of endotoxemia. "

I meant to write: " ...hypothermia CAN BE protective against the

harmful effects of endotoxemia. "

A topic like this doesn't lend itself to generalizations, and I

didn't mean to make one, just got sloppy...

> I've been able to read a bit the last couple days. I stumbled on

to

> some interesting things about the relationship between endotoxin

and

> body temperature.

>

> In this literature, elevated body temp is referred to as

> hyperthermia, depressed body temperature is referred to as

> hypothermia, and endotoxemia refers to illness due to circulating

> endotoxins.

>

> The first interesting thing I read was that endotoxemia can case

> BOTH hypothermia and hyperthermia.

>

> The second was that hypothermia is protective against the harmful

> effects of endotoxemia.

>

> The third was that hypothermia apparently induces the production

of

> anti-inflammatory cytokines like IL10, that help limit or moderate

> the inflammatory cascade which endotoxemia initiates. Here's a

link

> to one full-text paper on the subject:

>

> http://www.chestjournal.org/cgi/content/full/125/4/1483

>

> Is it too big a jump to ask if the sustained reduction in body

> temperature noted so many Lyme patients report might in fact be a

> response to endotoxemia?

>

> I wonder what others think.

>

>