Guest guest Posted July 9, 2005 Report Share Posted July 9, 2005 > I am working on some new angles on bacterial phenotypic resistance. I > need to know whether the Brown tx, etc, is more effective for those who > begin during their first couple years of illness, the way Dontas lyme > treatment and Wheldons MS treatment are. Anyone know? I am particularly > interested in those diseases whose cause is least likely to be > borrelial. The Nebraska Study (Dr O'Dell, 1995/1997), treated 46 RA patients with disease duration of less than 1 year. 65% of those treated with minocycline met the high criteria of 50% improvement during the trial, vs 13% placebo. Even more conclusively, 1/3 of the 24 Nebraska patients were reported to have remitted during the study. O'Dell followed his patients for over 3 years and 44% ultimately improved by 75% or more. The MIRA trial (1994?) involved 219 adults with RA for an average of 8 years. After 48 weeks, the study found that 54% of the patients taking minocycline had at least a 50% improvement in the number of swollen joints and 56% showed at least a 50% improvement in the number of tender joints. Does this help? (from The New Arthritis Breakthrough, Henry Scammell and Dr. McPherson Brown) Quote Link to comment Share on other sites More sharing options...
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