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Re: need info on Brown Protocol outcomes for theory

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> I am working on some new angles on bacterial phenotypic resistance.

I

> need to know whether the Brown tx, etc, is more effective for those

who

> begin during their first couple years of illness, the way Dontas

lyme

> treatment and Wheldons MS treatment are. Anyone know? I am

particularly

> interested in those diseases whose cause is least likely to be

> borrelial.

The Nebraska Study (Dr O'Dell, 1995/1997), treated 46 RA

patients

with disease duration of less than 1 year. 65% of those treated with

minocycline met the high criteria of 50% improvement during the

trial,

vs 13% placebo. Even more conclusively, 1/3 of the 24 Nebraska

patients

were reported to have remitted during the study. O'Dell followed his

patients for over 3 years and 44% ultimately improved by 75% or more.

The MIRA trial (1994?) involved 219 adults with RA for an average of

8

years. After 48 weeks, the study found that 54% of the patients

taking

minocycline had at least a 50% improvement in the number of swollen

joints and 56% showed at least a 50% improvement in the number of

tender joints.

Does this help? (from The New Arthritis Breakthrough, Henry Scammell

and Dr. McPherson Brown)

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