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barb, jim - white cells

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Jim - the norm ranges on my lab sheets for total white cell count are

3.5-10.8 for one lab, 4.0-11 for another. If you call the lab or the

doctor the norms will almost certainly be printed on the lab readout

right next to your values.

Barb - no, I have never been febrile this entire 2 years. Around the

time of the Jul 04 CBC when I had the out of range high monocytes, I

also had rather cloudy urine (tho I was normocalcemic, at least at

the time of the CBC), which could be consistant with high circulating

1,25d. This makes sense of course since 1,25d is produced during

intense inflammation, and favors commitment of pluripotent marrow

cells into the monocyte lineage. During that period I was amazingly

sick, as with a severe " flu " bug (most of what is refered to as flu

is not true influenza).

My (non-LL) university doc says 1000 neutros per uL is a place I

should aim to stay above. Presumably I was below that when I had the

2.7 total WBC count (didnt get the differential for that one).

<egroups1bp@y...> wrote:

> :

>

> It's common to have the white class (leukocytes) depressed

> while on abx- and your tests reflect that.

>

> Although - on JUL 04 when the monocytes were flagged as high you

> could have really had some sort of infection - or infection flare.

> Monocytes turn into cells (macrophages) that gobble up bacteria and

> they create cytokines in the process (did you have fever with this

> episode?) Usually the neutrophils are elevated during infection.

> Your neutros (also called granulocytes) are not elevated..and in

> fact are on the low side (So the monocytes have to do all the

work..)

>

> Neutrophiles are constantly shooting out of the bone marrow -in

some

> cases -almostly by the hr if they're needed for infection. They

have

> a very short life span.

> But they shouldn't be consistantly depressed as they're pretty

much

> the first line of defense at an injury (or infection ) site.

>

> Your test almost show neutropenia.. it could be from continual abx-

> or it could be from some other reason. Probably something you

should

> monitor.

>

> Barb

>

>

>

>

>

>

> > ...were back up to 3.7 once I stopped all drugs except the

> > antidepressant mirtazapine.

> >

> > You ask about my prior counts, esp neutros. Heres a sampling. I'd

> be

> > interested in your thoughts.

> >

> > NOV 03 minor depression and pelvic myoneuropathy, no drugs

> > WBC: 4.60

> > neutros: 1.9 [1.8-8.0]

> > neutros%: 41 LOW [47-82]

> >

> > MAY 04 moderate depression, anxiety, transient malaise, no drugs

> > WBC: 4.1

> > neutros: 1.8 [1.8-8.0]

> > neutros%: 44.5 LOW [47-82]

> >

> > JUL 04 mostly bed-ridden, suicidal neuritis, bad GI, etc etc,

> > no drugs

> > WBC: 4.6

> > granulocytes%: 37 [37-80]

> > lymphos%: 41 [10-50]

> > monocytes%: 21.9 HIGH [0-12]

> >

> > MAR 05 slowly improving, atovaquone, artemisin, doxy(400), zith

> > WBC: 3.6 LOW

> >

> > APRIL 05 mino, atovaquone, artemesin, zith

> > WBC: 3.7 LOW

> >

> > MAY 05 doxy, zith, and tini

> > WBC: 2.7 REAL LOW

> >

> > JUN 05 mirtazapine (antidepressant) only, feelin pretty normal

> many

> > days on the mirtaz, but exercise intolerant, lymphadenopathy,

> > transient malaise

> > WBC: 3.7 LOW

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