Guest guest Posted June 14, 2005 Report Share Posted June 14, 2005 hi paul - i for one, would be delighted to write a letter to the guy who denied your treatment - do you know his name and address, or an administrator in the plan? deb Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 9, 2006 Report Share Posted May 9, 2006 Thanks for this very kind note and for the good info about your own mitochondrial disease experiences and the major relief you got from Flagyll. Also the reminder about D-ribose, which I keep forgetting about but can be added to the drips I receive to make up for malabsorption problems. So in just a few replies, I have several action items, and that is just grand. Thank you. > > paul - this is so depressing - i've often wondered how you were doing - you used to write such wonderful posts.... > > my first workup was for mitochondrial myopathy with a muscle bx.....the neuro pathologist at davis said it didn't show much damage and i had to plead for him to send it to the lady in buffalo to get a definitive dx - some problems in the respiratory chain in complexes II, II-III....not enough to explain the sx.....i took the mito cocktail...didn't help..... > > however, for the past year i've been on flagyll......i acciudentally increased the dose to 1000 mg bid....was really sick for 10 days and then was miraculously better....much better! > > at about the same time i started dr stephen sinatra's protocol (d- ribose, l-carnitine, coq 10) and within 5 days felt a definite surge in energy which is still increasing.....i haven't followed any of the mito stuff for years and have no idea if d-ribose is discussed but it really seems to help me...... > > i will send you good thoughts and do hope you find something that will help, > deb > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 9, 2006 Report Share Posted May 9, 2006 I think Tony is pretty much right in that the wrong abx can cause problem with bacteria, but given our slant here is bacteria biased, I think Jeep general take being that the fungi is the untreated devil, and all abx cause fungi problems to worsen. This then being where attention should be placed. I think this group and others that are on the edge, such as cpnhelp, should consider more seriously the impact proper treatment that antifungals can achive. To give you a run down on my symptoms that have improved while on Lamisil and Fungizone: Prostate. (Much better) epididimal Cysts (no longer painful) Sinus problems (left side more) much better. Panic attacks (Much better) Colon (Working at last) Energy (Much better) Colour (I have some now) Body temp (Rising but still need extra to sleep well). Sleep, (Much better) This is one of the most wonderful aspects as well as the colon. I still have some problems but as you can see the general swing is on the up so one cannot complain and is looking forward to seeing what other miricals can be achived through long term antifungals. This is about close to 5 months now. Im planing if possibal to continue for at least a year. 18 months ideally BTW I think Diflucan is too expensive and not up to the job. IMO - Amp B (Much better). bleu On 9 May 2006, at 08:15, Schaafsma wrote: > Thanks for this very kind note and for the good info about your own > mitochondrial disease experiences and the major relief you got from > Flagyll. Also the reminder about D-ribose, which I keep forgetting > about but can be added to the drips I receive to make up for > malabsorption problems. > > So in just a few replies, I have several action items, and that is > just grand. Thank you. > > > > > > > > > > > > > paul - this is so depressing - i've often wondered how you were > doing - you used to write such wonderful posts.... > > > > my first workup was for mitochondrial myopathy with a muscle > bx.....the neuro pathologist at davis said it didn't show much > damage and i had to plead for him to send it to the lady in buffalo > to get a definitive dx - some problems in the respiratory chain in > complexes II, II-III....not enough to explain the sx.....i took the > mito cocktail...didn't help..... > > > > however, for the past year i've been on flagyll......i > acciudentally increased the dose to 1000 mg bid....was really sick > for 10 days and then was miraculously better....much better! > > > > at about the same time i started dr stephen sinatra's protocol (d- > ribose, l-carnitine, coq 10) and within 5 days felt a definite surge > in energy which is still increasing.....i haven't followed any of > the mito stuff for years and have no idea if d-ribose is discussed > but it really seems to help me...... > > > > i will send you good thoughts and do hope you find something that > will help, > > deb > > > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 9, 2006 Report Share Posted May 9, 2006  Untreated devil , I like that .it's good to see your improvement on AF's... I get a bit lonely sometimes beating the drum for AF's , you may like to add azithromicin to your mix , it acquires AF properties when used with Amph B [in the test tube ] It may be that you get the best of both worlds , effective against bac & fungi .. Looking at the synergy to be gained from using various drug combos , I found some very enlightening extracts quoting azithromycin combos …They highlight the Antifungal properties of the drug …It could explain the unexpected reactions to the drug…. The second extract found Azithromycin demonstrated no activity against Fusarium when tested alone but when combined with amphotericin B the killing power of the combo increased dramatically. The last extract explores the Antifungal effects of what is considered non Antifungal drugs …The message is clear … tap into the enhanced killing power and broader spectrum of combination drug treatment. . · · · · · Expert Opin Pharmacother. 2002 Nov;3(11):1541-2. Babesiosis in humans: a treatment review.Weiss LM.Division of Infectious Diseases, Albert Einstein College of Medicine, 1300 Park Avenue, Room 504 Forchheimer Building, Bronx, New York, 10461, USA. lmweiss@...Human infections with Babesia species, in particular Babesia microti, are tick-borne illnesses that are being recognised with increased frequency. Coinfection with ehrlichiosis and Lyme disease is also being recognised as an important feature of these tick-borne illnesses. Despite the superficial resemblance of Babesia to malaria, these piroplasms do not respond to chloroquine or other similar drugs. However, the treatment of babesiosis using a clindamycin-quinine combination has been successful. Data in animal models and case-reports in humans have suggested that an atovaquone-azithromycin combination is also effective. This was confirmed in a recent prospective, open, randomised trial of clindamycin-quinine versus azithromycin-atovaquone. This paper reviews the literature on the treatment of human babesiosis and the animal models of these human pathogens.Publication Types: · Review · Review, Academic PMID: 12150690 [PubMed - indexed for MEDLINE] J Antimicrob Chemother. 1998 Jan;41(1):127-30. Related Articles, Links The combination of amphotericin B and azithromycin as a potential new therapeutic approach to fusariosis.Clancy CJ, Nguyen MH.Department of Medicine, University of Florida College of Medicine, Gainesville 32610, USA.We investigated the interaction between amphotericin B and azithromycin in vitro against 26 clinical isolates of Fusarium. Synergy was demonstrated in all isolates. Amphotericin B MICs were reduced from a mean of 1 mg/L when tested alone to a mean of 0.37 mg/L when tested in combination with azithromycin. Azithromycin demonstrated no activity against Fusarium when tested alone (MIC > 128 mg/L). When combined with amphotericin B the mean MIC was reduced to 5.5 mg/L, a level readily achieved in tissue. Given the resistance of Fusarium to conventional therapy, the in-vitro synergy between amphotericin B and azithromycin might prove to be important in therapy for fusariosis.PMID: 9511049 [PubMed - indexed for MEDLINE] Article European Journal of Clinical Microbiology & Infectious Diseases Publisher: Springer-Verlag Heidelberg ISSN: 0934-9723 (Paper) 1435-4373 (Online) DOI: 10.1007/s10096-003-0947-x Issue: Volume 22, Number 7 Date: July 2003 Pages: 397 - 407 Review Antifungal Activity of Nonantifungal Drugs J. Afeltra1, 2 and P. E. Verweij1, 2 (1) Department of Medical Microbiology, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands (2) Nijmegen University Center for Infectious Diseases, Nijmegen, The Netherlands Published online: 26 June 2003 Abstract The antifungal activity of synthetic, nonchemotherapeutic compounds, antineoplastic agents and antibacterial drugs, such as sulphonamides, has been known since the early 20th century (1932). In this context, the term "nonantifungal" is taken to include a variety of compounds that are employed in the management of pathological conditions of nonfungal infectious etiology but have been shown to exhibit broad-spectrum antifungal activity. In this review, the antifungal properties of compounds such as chlorpromazine, proton pump inhibitors, antiarrhythmic agents, cholesterol-lowering agents, antineoplastic and immunosuppressive agents, antiparasitic drugs and antibiotics are described. Since fungi are eukaryotic cells, they share many pathways with human cells, thus increasing the probability of antifungal activity of "nonfungal drugs". The potential of these drugs for treatment of fungal infections has been investigated sporadically using the drugs alone or in combination with "classic" antifungal agents. A review of the literature, supplemented with a number of more recent investigations, suggests that some of these compounds enhance the activity of conventional antifungal agents, eliminate natural resistance to specific antifungal drugs (reversal of resistance) or exhibit strong activity against certain fungal strains in vitro and in animal models. The role of these agents in the epidemiology and in the clinical manifestations of fungal infections and the potential of certain drugs for treatment of invasive fungal infections require further investigation. P. E. VerweijEmail: p.verweij@...Phone: +31-24-3614356Fax: +31-24-3540216 The references of this article are secured to subscribers. Previous articleNext article Linking Options You are not logged in. The full text of this article is secured to subscribers. You or your institution may be subscribed to this publication. If you are not subscribed, this publisher offers secure article or subscription sales from this site. Please select 'Continue' to view your options for obtaining the full text of this article. Continue http://tinyurl.com/4xr3k http://ist-socrates.berkeley.edu/~alanburr/physiol/webcc99/cccase3.99.htm -----Original Message-----From: infections [mailto:infections ]On Behalf Of ColourbleuSent: 09 May 2006 08:46infections Subject: Re: [infections] Re: agent schaI think Tony is pretty much right in that the wrong abx can cause problem with bacteria, but given our slant here is bacteria biased, I think Jeep general take being that the fungi is the untreated devil, and all abx cause fungi problems to worsen. This then being where attention should be placed.I think this group and others that are on the edge, such as cpnhelp, should consider more seriously the impact proper treatment that antifungals can achive.To give you a run down on my symptoms that have improved while on Lamisil and Fungizone:Prostate. (Much better)epididimal Cysts (no longer painful)Sinus problems (left side more) much better. Panic attacks (Much better)Colon (Working at last)Energy (Much better)Colour (I have some now)Body temp (Rising but still need extra to sleep well).Sleep, (Much better) This is one of the most wonderful aspects as well as the colon.I still have some problems but as you can see the general swing is on the up so one cannot complain and is looking forward to seeing what other miricals can be achived through long term antifungals. This is about close to 5 months now. Im planing if possibal to continue for at least a year. 18 months ideallyBTW I think Diflucan is too expensive and not up to the job. IMO - Amp B (Much better).bleuOn 9 May 2006, at 08:15, Schaafsma wrote: Thanks for this very kind note and for the good info about your own mitochondrial disease experiences and the major relief you got fromFlagyll. Also the reminder about D-ribose, which I keep forgetting about but can be added to the drips I receive to make up for malabsorption problems.So in just a few replies, I have several action items, and that is just grand. Thank you.>> paul - this is so depressing - i've often wondered how you were doing - you used to write such wonderful posts....> > my first workup was for mitochondrial myopathy with a muscle bx.....the neuro pathologist at davis said it didn't show much damage and i had to plead for him to send it to the lady in buffalo to get a definitive dx - some problems in the respiratory chain in complexes II, II-III....not enough to explain the sx.....i took the mito cocktail...didn't help.....> > however, for the past year i've been on flagyll......i acciudentally increased the dose to 1000 mg bid....was really sick for 10 days and then was miraculously better....much better!> > at about the same time i started dr stephen sinatra's protocol (d-ribose, l-carnitine, coq 10) and within 5 days felt a definite surge in energy which is still increasing.....i haven't followed any of the mito stuff for years and have no idea if d-ribose is discussed but it really seems to help me......> > i will send you good thoughts and do hope you find something that will help,> deb> Quote Link to comment Share on other sites More sharing options...
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