Guest guest Posted June 14, 2005 Report Share Posted June 14, 2005 I contacted Wheldon about this study to ask about the lack of metronidazole. He said that the main purpose of this was to demonstrate that the reduction of Cpn in cerebrospinal fluid and the reduction in lesions in MS was not due to anti-inflammatory effects of the abx. Both these abx are considered to not have anti-inflam effects. So this was a scientific study, in part, to respond to critique and sort out those variables. As an indicator of how meticulous this whole line of research by Stratton, et al has been, they even used riboflavin in the placebo to make the urine the same color as that from the abx! From Wheldon: " Chuck Stratton has sent me this study. I believe that metronidazole wasn't used because it isn't an accepted chlamydicide, and the authors wanted as few improbables as possible... There is a great deal in the full-text article which is not covered in the abstract. For instance, although there was no shrinkage of enhancing lesions during the period of study, post-study MRIs did show lesion shrinkage in this group. The study was meticulous, even to the point of giving the placebo group riboflavin to give the urine the same colouration as rifampicin. " Great to see good science. Jim Quote Link to comment Share on other sites More sharing options...
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