Guest guest Posted June 17, 2005 Report Share Posted June 17, 2005 That sounds like its probably an immunological reaction. Aspirin is one or two carbon rings, really too small to make antibodies against, but it seems that immune reactivity still happens somehow in some people. Possibly by the drug binding to certain self-proteins, creating a complex that is treated by the immune system as foreign, even tho the molecule standing by itself is too small to be treated as foreign. There has been some study of this... I dont know much about it. > > >then I got polyps and aspirin sensitivity > > > > > > --------------------------------- > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 20, 2005 Report Share Posted June 20, 2005 Dear The thing is does an overreacting immunulogical response happen just like that or is it because of an infection that triggers it Hodologica <usenethod@...> wrote: That sounds like its probably an immunological reaction. Aspirin is one or two carbon rings, really too small to make antibodies against, but it seems that immune reactivity still happens somehow in some people. Possibly by the drug binding to certain self-proteins, creating a complex that is treated by the immune system as foreign, even tho the molecule standing by itself is too small to be treated as foreign. There has been some study of this... I dont know much about it.> > >then I got polyps and aspirin sensitivity> > > > > > ---------------------------------> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 20, 2005 Report Share Posted June 20, 2005 Actually I have to take back both points of what I said. Aspirin has only one ring, but more importantly, I saw a reference to aspirin allergy in a chem textbook. I dont know much about MCS, or atopy, asthma, but it seems pretty clear MCS is related to infection... I know infection models of asthma have been explored (esp re Chlamydia pneumoniae). Without having read anything, yes I think these kinds of reactivity could be immune hyperactivity due to infection. As in, the IS " lowering its standards " for what to get worked up about, due to persistant stimulation from microbes. In ordinary pulmonary tuberculosis, it seems a number of autoantibodies crop up. Conversely, however, sarcoidosis is famous for under-reaction when certain antigens are injected subcutaneously. So by no means is everything cut & dry. > > > >then I got polyps and aspirin sensitivity > > > > > > > > > > > > --------------------------------- > > Quote Link to comment Share on other sites More sharing options...
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