Re: Tom Grier/Neuro article

[Guest guest]

Interesting and scary.

Also, kind of corroborates what I've been rethinking myself on the

whole 'PWCs shouldn't have any sugar' dictum, because when I'm most

fatigued, which includes severe mental fatigue, I crave sugar (this

is a recent development over the last year or so). This article says

that CFS patients show a relief of fatigue when glucose levels in

the brain are artificially elevated. Same with diabetics who let

their blood sugar go a little higher than usual.

This last week, my energy's back up and the sugar cravings are gone.

One thing that's odd is that since my energy's come back, the back

of my head, at the base of my skull, is itching again, pretty

intensely, just as it did when I started Benicar. And during the

last 6 weeks of intense fatigue, my neck was stiff on the left side

(it's been stiff on the right my whole life, until Benicar). Now the

fatigue is lifted, the sugar cravings are gone, and the back of my

head is itching like crazy again. I feel like there's a battle going

on in my head and the abx are winning right now. But who knows why

and for how long? Why did it take so long for the zithromax to do

this? It seems like it took a long time to calm down the sinus

thing. Now that it has, the back of my head's being targeted?

penny

> PWCF, note the discussed NMDA receptors.

> And the use of Magnesium -

> And steroids.

>

> http://flash.lymenet.org/ubb/Forum1/HTML/034124.html

[Guest guest]

DEXTROMETHORPHAN not dextropromorphan. It's an opioid-style thing for anyone who might want to look it up

http://www.erowid.org/chemicals/dxm/dxm_journal1.shtml

I have had a personal relationship with medication that contain codeine as they are the only pain meds that give me any relief.

When I was young and naive (and first sick) I used to think doctors were going to be interested in investigating why codeine helped me, often making me feel much better even 24hrs after taking one dose.

Nelly

The second agent to block NMDA receptors is the common OTC cough suppressant dextropromorphan or DM. Dextropromorphan binds to the NMDA receptor but does not have the same effect as the neurotoxins that over stimulate the NMDA receptor. In low doses it appears to have a similar but more pronounced affect as magnesium and some Lyme patients with neurocognitive deficits report after a single oral dose of 30-60 mgs that they have an improvement of mental clarity, energy and ability to multi-task. Since these are only anecdotal accounts, we cannot draw any conclusions as to safety or efficacy until blinded studies are completed. Unfortuantely dextropromorphan like many OTC medications has a history of being abused. Dextropromorthan is nonaddicting but in high single doses of 600-1,200 mgs can cause a hallucinogenic euphoria-like state, and at these dosages has been observed to cause some measurable brain changes and brain damage. It would be a shame if such a simple treatment modality that has been safe and effective at OTC doses for 40 years would be withdrawn from the market just when it may prove to be useful in the treatment of Lyme and potentially other NMDA mediated diseases such as Multiple Sclerosis and Parkinson’s disease where NMDA receptors are also over stimulated. It is conceivable that dextropromorphan taken immediately after a brain injury or boxing match could have a slight amelioration affect of brain trauma by blocking the effects of glutamate flooding the NMDA receptors immediately after a brain trauma? I am sorry to say that I could find no studies to reference this possible usage of dextromethorphan. Dextropromorphan also has a pronounced anesthetic effect at high doses similar to the related drug Ketomin/ketomine. It’s role as a treatment modality for Lyme, MS, and sports injuries has not yet been evaluated, but in theory host-receptor blocking offers some hope in the direction that new therapies could take in years to come. Tom Grier

[infections] Tom Grier/Neuro article

PWCF, note the discussed NMDA receptors. And the use of Magnesium -And steroids.http://flash.lymenet.org/ubb/Forum1/HTML/034124.html