Guest guest Posted June 8, 2005 Report Share Posted June 8, 2005 Interestin'. I want to find out more but I am not finding anything in pubmed or google - any leads? <msmabrry@y...> wrote: > I believe there is a Dr. Ryle in Carmichael, CA who > subscribes to the vasculitis theory. I think he was > one of the first Docs in US to study CFS. > Marie > --- Hodologica <usenethod@y...> wrote: > > > > I feel vasculitis should be another leading suspect. > > This could cause > > poor perfusion in the brain. And, as Cheney > > brainstorms, it could > > self-intensify, if poor perfusion of the heart were > > itself to > > compromise heart function and thence circulation, in > > a vicous cycle. > > > > Microvasculitis impacts perfusion by simply > > deforming/narrowing the > > capillaries. Endothelial (vessel wall) cells swell > > and reproduce > > abnormally. This has the potential to completely > > stagnate the capillary. > > > > Vasculitis and perivasculitis are the most > > ubiquitous lesions of > > syphilis. Vasculitis has also been found often in > > lyme in many cases. > > (I dont know for sure of any whole tissue histology > > of lyme; if there > > were any I wonder if vasculitis *might* be found to > > in fact feature in > > every case. I get a vague sense that histology of > > needle biopsy > > samples may not be as good as autopsy in some ways, > > but I am > > uncertain. I do not remember whether all the lyme > > histology I know of > > is on needle-biopsy material). > > > > Al, I didnt know Goldstein had shown hypoperfusion > > via SPECT - thats > > very interesting. Do you know why this finding didnt > > silence the > > psychologizing school of CFS/ME? Do you know of any > > non-needle > > histology on CFS/ME or chronic borreliosis? I have > > looked a bit but > > found little. The only CFS histology I found was > > muscle biopsies where > > myocytes (muscle cells) were primarily examined. One > > would think the > > investigators would have noticed any vasculitis if > > present but who > > knows. Rich, you really know CFS literature so > > perhaps you have some > > insight? > > > > > > > > > > > Hi all, > > > > > > > > The SPECT Brain Scans that were done in the > > early 90's by Jay > > > Goldstein & others on CFS patients showed > > > > Hypoperfusion (Low Blood Flow). > > > > > > > > As a result of the Peckerman study, Dr. Cheney > > says the result of > > > the low cardiac output in CFS is poor > > micro-circulation . It would > > > appear that this is what caused the > > Hypoperfusion in the SPECT > > > Scans. Right ? > > > > > > > > > > > > Al > > > > Quote Link to comment Share on other sites More sharing options...
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