Re: Penny-What is your theory on low dose ABX results?

[Guest guest]

Hi Jelly,

I wouldn't want to work toward taking ANY minocycline. I will stick

with alternatives.

I definitely do not believe that the low dose is more effective in

killing. If anything, I think it stirred up my infection, while also

being toxic to my system over time. I definitely think that

minocycline builds up in my tissue, and becomes more toxic for me as

time passes. I don't seem to be able to process it out of my body like

most people do.

The reason the minocycline reaction was worse on low dose, was because

it made my heart crazy, but didn't affect my heart at normal doses or

i.v. I was just as ill on both doses, but didn't have the heart scare

(which landed me in the E.R.). I think this could be because the dose

wasn't effective enough to kill the bacteria affecting my heart,

rather it stimulated them, but was still enough to induce the toxicity

symptoms as it built up in my tissue.

My friend, who has graves disease/hyperthyroid, and has been taking

minocin for the last couple of months, is freaked right now because

her thyroid's all screwed up. Her numbers are completely messed up

(reading hypo while having terrible hyper symptoms - similar to what

happened to me). She stopped the mino, increased her anti-thyroid meds

and has finally started feeling better. She thinks it's due to the

mino.

Obviously, this doesn't happen to everyone. My daughter and a friend

both do well on minocin. But it has these known side effects in some

people which can't be dismissed, because different people react

differently.

Minocin can cause pseudotumor cerebri, can screw with your thyroid,

can induce lupus, and perhaps, based on these articles, could even be

causing secondary porphyria in people. (Doxycycline doesn't do these

things, although I don't know about the porphyia).

The point is, such negative reactions cannot be dismissed or lauded

as " herxes " , because in fact, some of these reactions can permanently

harm (pseudotumor cerebri can blind you), even kill you.

penny

> Hi Penny

>

> I was just wondering what your thoughts are on why you have a more

> serious reaction when you take lower dose Minocycline? Do you feel

> like Trevor suggests, that the lower dose is more likely the

stronger

> kill zone? If that is the case would you want to work towards taking

> less, or more?

[Guest guest]

Thanks Penny,

We all do respond so differently. Doxy put me in the ER with my

heart going crazy and BP on the floor. I was at full dose then.

Decreased the dose and symptoms subsided but the swelling in my feet

and ankles was to much. They were red and hot and felt like bone

grinding on bone. I swithced to low dose minocycline and have done

GREAT, even as low as 3 mgs every other day. It would be so nice and

easy if we all responded to the ABX in the same way. I too believe

that it seem to accumulate in my tissues though.

Thanks for your thoughts.

> > Hi Penny

> >

> > I was just wondering what your thoughts are on why you have a

more

> > serious reaction when you take lower dose Minocycline? Do you

feel

> > like Trevor suggests, that the lower dose is more likely the

> stronger

> > kill zone? If that is the case would you want to work towards

taking

> > less, or more?

[Guest guest]

Yes, exactly, we all react differently. That's why it's frustrating

when people come up with protocols using only certain abx and won't

allow substitutions. Not only are we colonized differently, with a

variety of organisms that are mutated differently, there are other

factors such as the way we metabolize drugs, that can cause

reactions as well.

That's why I really wish our doctors would do routine testing of our

bugs, to at least get some information to help us predict how we

will respond to different drugs. I know that having my organisms

tested helped me tremendously in knowing which drugs to take, and

which to not bother with (which was a long list, since my bugs were

already resistant to so many abx).

Of course, testing's not fool proof either. Testing showed

minocycline would be a good drug for killing my bugs, but I just

could't handle it, and no way will anyone convince me it's due

to " herxing " . I know when I'm being poisoned, versus when I'm

experiencing die-off.

penny

> Thanks Penny,

>

> We all do respond so differently. Doxy put me in the ER with my

> heart going crazy and BP on the floor. I was at full dose then.

> Decreased the dose and symptoms subsided but the swelling in my

feet

> and ankles was to much. They were red and hot and felt like bone

> grinding on bone. I swithced to low dose minocycline and have done

> GREAT, even as low as 3 mgs every other day. It would be so nice

and

> easy if we all responded to the ABX in the same way. I too believe

> that it seem to accumulate in my tissues though.

>

> Thanks for your thoughts.

>