clinical courses of neuroLyme after ceftriaxone

[Guest guest]

Obvious problems with this abstract - a poorly defined use of the

word " cure, " a very brief treatment period of 2-3 weeks, etc. I

decided to post it anyway, because it's fairly recent and if one

spoke German the full paper might be interesting.

Nervenarzt. 2004 Jun;75(6):553-7.

[Clinical courses of acute and chronic neuroborreliosis following

treatment with ceftriaxone]

[Article in German]

Kaiser R.

Neurologische Klinik, Stadtisches Klinikum Pforzheim.

Kaiser.Neurologische_Klinik@...

Between 1990 and 2000, a total of 101 patients with acute (n=86) or

chronic (n=15) neuroborreliosis (proven by clinical data,

pleocytosis in the CSF, and elevated Borrelia burgdorferi-specific

antibody indices) were treated with 2 g of ceftriaxone per day for

either 2 or 3 weeks. The patients were reexamined clinically and

serologically after 3, 6, and 12 months. Six (12) months after the

antibiotic treatment, about 93% (95%) of the patients with acute

neuroborreliosis and 20% (66%) of the patients with chronic

neuroborreliosis were cured. One year after treatment, four patients

with acute neuroborreliosis still suffered from facial palsy and

five with chronic neuroborreliosis still had moderate spastic ataxic

gait disturbance. The prognosis of facial palsy in neuroborreliosis

is quite similar to that in idiopathic facial palsy, while that in

chronic neuroborreliosis largely depends on the time elapsed before

diagnosis.

Publication Types:

Clinical Trial

Controlled Clinical Trial

PMID: 15257378 [PubMed - indexed for MEDLINE]