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brain SPECT, CFS

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Just took a gander at the brain SPECT and CFS literature. There are

actually a number of studies looking at this, and frankly, the data

are all over the place. There isn't a whole lot of consistency in (A)

differences between normal controls & CFS patients (saw a very nice

twin study but no significant differences), (B) depressive controls

and CFS patients, and © in studies that find differences, the brain

regions affected differ from study to study. In short, the findings

are variable at this point. I'm sure as more work is done, the

results will shake out, but at this point, the data simply aren't

converging on a clear pattern yet.

Also, should anything consistent be found on SPECT imaging for CFS

patients, we need to keep in mind that a number of processes can yield

the differences observed on a SPECT scan.... making links between

brain SPECT in CFS and other physiological findings would be, alas,

quite premature.

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