Guest guest Posted June 3, 2005 Report Share Posted June 3, 2005 Barb - yes, the IV does contain other things (its called a Meyers drip) but it does include high amounts of Mg I'm told, and I attribute the anti-twitch effect to that ingredient based on others' experience. - many thanks for the idea. I take it you are saying the laxative dose of the sulfate is so high probably because most of the compound is absorbed (due to its high water solubility) before reaching the lower GI and acting laxatively there. Very interesting. Taking the sulfate orally would certainly be more convenient than parenteral administration. (Slow-release Mg orals are also totally inconvenient because of the possibility, as I understand things, that Mg may bind cyclines and azithromycin etc in the GI, impairing their absorbtion). > Dear > There Is evidence( claims) that magnesium availability is directly related to the solubility. After ruling out fluorides and nitrates on the basis of toxicity, the next most soluble and available is the chloride( remembering that most reactive compounds are converted to chlorides in the stomach by the natural stomach production of hydrochloric acid). Even more freely available is the sulphate( also highly soluble). As all magnesium compounds are laxative to some extent it is useful to compare the laxative doses. Some of the low solubility compounds such as carbonates and oxides have a laxative effect at 300 milligrams. The sulphate is commonly given as a laxative at 30 grams. A number of orders of magnitude greater dose. I use the sulphate at half a teaspoon a day with no laxative effect. It may be worth trying as the sulphate is dirt cheap.. There is also evidence to show that boron deficiency affects magnesium uptake. > Regards > Windsor Quote Link to comment Share on other sites More sharing options...
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