Re: magnesium deficiency - test?

[Guest guest]

Dear

There Is evidence( claims) that magnesium availability is directly related to the solubility. After ruling out fluorides and nitrates on the basis of toxicity, the next most soluble and available is the chloride( remembering that most reactive compounds are converted to chlorides in the stomach by the natural stomach production of hydrochloric acid). Even more freely available is the sulphate( also highly soluble). As all magnesium compounds are laxative to some extent it is useful to compare the laxative doses. Some of the low solubility compounds such as carbonates and oxides have a laxative effect at 300 milligrams. The sulphate is commonly given as a laxative at 30 grams. A number of orders of magnitude greater dose. I use the sulphate at half a teaspoon a day with no laxative effect. It may be worth trying as the sulphate is dirt cheap.. There is also evidence to show that boron deficiency affects magnesium uptake.

Regards

Windsor

[infections] magnesium deficiency - test?

I may need to transfer my primary care to a non-LL for convenience. I have been getting IV magnesium about once a month. I dont know a thing about it except that it ablates my muscle twitching immediately, which is useful because I meditate. I currently havent had an IV in a month, and am starting to twitch a little, so maybe I could establish myself as magnesium-deficient by getting an intracellular Mg assay of some kind done? Anyone know how this works, whether a non-LL would have easy access to the assay, and whether I would be likely to be clinically deficient by non-LL standards? Or know any literature supporting Mg deficiency in lyme or CFS? THanx

[Guest guest]

I know I keep harping on the fact that minerals should be taken

together and in the right ratios- so I'll keep harping.

The bioavaiabilty of all the elements depends on the form and it

depends on the status of other minerals. Dose and form will affect

the bowel intolerance levels (that's when Mg is used as a laxative).

The body will also substitute one element for another if one

is in short supply... then reset the body.

Most people are deficient in magnesium because it's just not in the

food supply any more at the levels it used to be and it's not in the

(electrolyte) replacement drinks. If it alleviates muscletwitching-

then you can be sure you need to supplement. But I wouldn't just

take it alone. Are you sure there's not something else in your IV

too?

Barb

> Dear

> There Is evidence( claims) that magnesium availability is directly

related to the solubility. After ruling out fluorides and nitrates on

the basis of toxicity, the next most soluble and available is the

chloride( remembering that most reactive compounds are converted to

chlorides in the stomach by the natural stomach production of

hydrochloric acid). Even more freely available is the sulphate( also

highly soluble). As all magnesium compounds are laxative to some

extent it is useful to compare the laxative doses. Some of the low

solubility compounds such as carbonates and oxides have a laxative

effect at 300 milligrams. The sulphate is commonly given as a

laxative at 30 grams. A number of orders of magnitude greater dose. I

use the sulphate at half a teaspoon a day with no laxative effect. It

may be worth trying as the sulphate is dirt cheap.. There is also

evidence to show that boron deficiency affects magnesium uptake.

> Regards

> Windsor

> [infections] magnesium deficiency - test?

>

>

> I may need to transfer my primary care to a non-LL for

convenience. I

> have been getting IV magnesium about once a month. I dont know a

thing

> about it except that it ablates my muscle twitching immediately,

which

> is useful because I meditate.

>

> I currently havent had an IV in a month, and am starting to

twitch a

> little, so maybe I could establish myself as magnesium-deficient

by

> getting an intracellular Mg assay of some kind done?

>

> Anyone know how this works, whether a non-LL would have easy

access to

> the assay, and whether I would be likely to be clinically

deficient by

> non-LL standards? Or know any literature supporting Mg deficiency

in

> lyme or CFS? THanx

>

>

>

>

> --------------------------------------------------------------------

----------

>

[Guest guest]

> I know I keep harping on the fact that minerals should be taken

> together and in the right ratios- so I'll keep harping.

>

> The bioavaiabilty of all the elements depends on the form and it

> depends on the status of other minerals. Dose and form will affect

> the bowel intolerance levels (that's when Mg is used as a

laxative).

>

> The body will also substitute one element for another if one

> is in short supply... then reset the body.

>

> Most people are deficient in magnesium because it's just not in

the

> food supply any more at the levels it used to be and it's not in

the

> (electrolyte) replacement drinks. If it alleviates muscletwitching-

> then you can be sure you need to supplement. But I wouldn't just

> take it alone. Are you sure there's not something else in your IV

> too?

>

> Barb

>

Hi Barb

I had been thinking a lot about bioavailabilty of our supplements so

I have decided for the most part to get my minerals in the form of

the green foods that are in Garden of Life's Perfect Food. In

addition I do take extra magnesium citrate from time to time if my

muscles seem particularly affected and I also have to add in extra

sea salt because of my weak adrenals. Its nearly a month I have

been taking 2 tsp x 2 daily of the Perfect Food in addition to

Thorne's whey protein with lactoferrin.

I also take extra Bs and Vitamin C plus a good quality Cod Liver Oil

and these all seem to be working well, my energy has been

excellent. The only problem I get is from the flucanazole blocking

the Prednisolone I take so I have found that I have to take extra

hydrocortisone to compensate for this. I have had some of the best

days I have had in years but they will often be followed by some

severe migraines which I guess is a side effect of the flucanazole.

At the moment I can only tolerate 75mg flucanazole daily or even

every other day on some occasions.

Pam

[Guest guest]

Geez Pam.. That's great news, as I know you've had a hard time of

it.

You're tailoring your therapy to your needs- which I think has to be

done in alot of cases.

Have you pretty much narrowed the headaches (migraines) to

fluconazole? I think headache is listed as being possible in about

2% of the people that take fluconazole.

Are the head aches new? Or is this a pre-exisiting condition.

Keep us posted.

Sounds like you are on the right track.

Barb

> > I know I keep harping on the fact that minerals should be taken

> > together and in the right ratios- so I'll keep harping.

> >

> > The bioavaiabilty of all the elements depends on the form and it

> > depends on the status of other minerals. Dose and form will

affect

> > the bowel intolerance levels (that's when Mg is used as a

> laxative).

> >

> > The body will also substitute one element for another if one

> > is in short supply... then reset the body.

> >

> > Most people are deficient in magnesium because it's just not in

> the

> > food supply any more at the levels it used to be and it's not in

> the

> > (electrolyte) replacement drinks. If it alleviates

muscletwitching-

>

> > then you can be sure you need to supplement. But I wouldn't just

> > take it alone. Are you sure there's not something else in your

IV

> > too?

> >

> > Barb

> >

> Hi Barb

>

> I had been thinking a lot about bioavailabilty of our supplements

so

> I have decided for the most part to get my minerals in the form of

> the green foods that are in Garden of Life's Perfect Food. In

> addition I do take extra magnesium citrate from time to time if my

> muscles seem particularly affected and I also have to add in extra

> sea salt because of my weak adrenals. Its nearly a month I have

> been taking 2 tsp x 2 daily of the Perfect Food in addition to

> Thorne's whey protein with lactoferrin.

>

> I also take extra Bs and Vitamin C plus a good quality Cod Liver

Oil

> and these all seem to be working well, my energy has been

> excellent. The only problem I get is from the flucanazole blocking

> the Prednisolone I take so I have found that I have to take extra

> hydrocortisone to compensate for this. I have had some of the best

> days I have had in years but they will often be followed by some

> severe migraines which I guess is a side effect of the

flucanazole.

> At the moment I can only tolerate 75mg flucanazole daily or even

> every other day on some occasions.

>

> Pam

[Guest guest]

> Geez Pam.. That's great news, as I know you've had a hard time of

> it.

>

> You're tailoring your therapy to your needs- which I think has to

be

> done in alot of cases.

>

> Have you pretty much narrowed the headaches (migraines) to

> fluconazole? I think headache is listed as being possible in

about

> 2% of the people that take fluconazole.

>

> Are the head aches new? Or is this a pre-exisiting condition.

>

> Keep us posted.

> Sounds like you are on the right track.

>

> Barb

>

Hi Barb

No the headaches are not new, in fact they are always migraineous

and have been one of my worst problems for many years and its

definitely linked to the flucanzole. What it is happenining is that

it is blocking the effect of the Prednisolone and my blood sugar is

very unstable. I have to keep eating in order to feel well and I am

rather fed up because I have put on 3lbs in weight in the 2 weeks I

have been taking the flucanzole. I definitely don't need this

weight gain but I will try and perserve.

BTW Have you been hearing about the gene testing that can be done?

From one blood sample they can test our blood to see how we

metabolize drugs. There is a brilliant website explaining that some

of us could be very slow metabolizers of drugs and therefore we only

need half or less of a normal dose of drugs. I am seriously

thinking of getting this done I have found a company in the UK that

can do this. Obviously it has to be arranged through one's doctor

but I am sure it is the way forward. My history has always been

that I have only needed tiny doses of drugs, in fact it would seem

to be genetic because my father and aunt also seem to have this

problem.

For the moment I have lost the link to the website but I have

emailed the BBC who did an excellent programme about this last

week. When I find the link I will post it.

Best Wishes

Pam

[Guest guest]

I think I also heard that report. They're looking at what's

called pleomorphism in the P450 enzyme system (first pass is

thru the intestines where there are some P450 enzymes, and next

pass is thru the liver). SO for drugs being metabolized thru this

route, they'll know which ones are different from the average

population.

It'd be great if that was a routine test.

Barb

> > Geez Pam.. That's great news, as I know you've had a hard time of

> > it.

> >

> > You're tailoring your therapy to your needs- which I think has to

> be

> > done in alot of cases.

> >

> > Have you pretty much narrowed the headaches (migraines) to

> > fluconazole? I think headache is listed as being possible in

> about

> > 2% of the people that take fluconazole.

> >

> > Are the head aches new? Or is this a pre-exisiting condition.

> >

> > Keep us posted.

> > Sounds like you are on the right track.

> >

> > Barb

> >

> Hi Barb

>

> No the headaches are not new, in fact they are always migraineous

> and have been one of my worst problems for many years and its

> definitely linked to the flucanzole. What it is happenining is

that

> it is blocking the effect of the Prednisolone and my blood sugar is

> very unstable. I have to keep eating in order to feel well and I

am

> rather fed up because I have put on 3lbs in weight in the 2 weeks I

> have been taking the flucanzole. I definitely don't need this

> weight gain but I will try and perserve.

>

> BTW Have you been hearing about the gene testing that can be

done?

> From one blood sample they can test our blood to see how we

> metabolize drugs. There is a brilliant website explaining that

some

> of us could be very slow metabolizers of drugs and therefore we

only

> need half or less of a normal dose of drugs. I am seriously

> thinking of getting this done I have found a company in the UK that

> can do this. Obviously it has to be arranged through one's doctor

> but I am sure it is the way forward. My history has always been

> that I have only needed tiny doses of drugs, in fact it would seem

> to be genetic because my father and aunt also seem to have this

> problem.

>

> For the moment I have lost the link to the website but I have

> emailed the BBC who did an excellent programme about this last

> week. When I find the link I will post it.

>

> Best Wishes

>

> Pam