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Is milk thistle ok to take if taking daily flucanzole

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Does anybody know if it is ok to continue to take milk thistle if one

is going to take a daily flucanazole? Usually I take 2 or 3 milk

thistle capsules daily but was wondering if this is a good idea

because I believe it acts on the P450 system as does flucanzole.

I think this is a problem with flucanzole it is contraindicated with

so many other meds and maybe supplements too. It gave me a horrendous

central nervous system reaction because I had taken it when Plaquenil

was still in my system and possibly erthyromycin too. It took a week

and a half to for the reaction to settle down and hope I don't have to

go through that again.

Thanks

Pam

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