Re: Cpn resistance

[Guest guest]

I haven't read the specific study you guys are

referring to, but it seems consistent with what

Stratton's work found: that Cpn is actively

replicating inter-cellularlly and susceptable to abx,

but in it's non-replicating phase it is inside cells

(like those mentioned) where they protect themselves

in a more dormant state. Abx mostly interfere with

replication. The use of abx winnows down the

intercellular bacteria, and others move into cells and

are protected. This is the heart of all of Stratton's

findings on Cpn.

This is why the flagyl (metronidazole) is used in his

protocal: it kills them in the non-replicating

intracellular phase. The cells are indeed a " bunker "

for dormant

I wrote an email to Stratton asking him specifically

about the Wheldon version of his protocal, since

Wheldon's recommendations are a bit different in terms

of the ongoing abx. Stratton wrote me back saying that

the doxy/zithro combo was fine, but the flagyl is the

key. Pretty much a direct quote.

Jim

[Guest guest]

I wrote an email to Stratton asking him specificallyabout the Wheldon version of his protocal, sinceWheldon's recommendations are a bit different in termsof the ongoing abx. Stratton wrote me back saying thatthe doxy/zithro combo was fine, but the flagyl is thekey. Pretty much a direct quote.

Hi,

Did Stratton say whether tinidazole could be used instead of metronidazole? And whether any cycline/macrolide combo would do? I am doing spiramycine + doxy (also taking artemisinin for Babs) and tinidazole 5 days every 3 weeks.

I am about to embark on my 2nd period with tinidazole and after that I am thinking of switching to another cycline/macrolide combo (mino/pristinamycine-it's a 2 macrolide macrolide), still taking artemisinin btwn 200 mg/day and 200 mg X2 day.

Any comments welcome

Nelly

[infections] Re: Cpn "resistance"

I haven't read the specific study you guys arereferring to, but it seems consistent with whatStratton's work found: that Cpn is activelyreplicating inter-cellularlly and susceptable to abx,but in it's non-replicating phase it is inside cells(like those mentioned) where they protect themselvesin a more dormant state. Abx mostly interfere withreplication. The use of abx winnows down theintercellular bacteria, and others move into cells andare protected. This is the heart of all of Stratton'sfindings on Cpn.This is why the flagyl (metronidazole) is used in hisprotocal: it kills them in the non-replicatingintracellular phase. The cells are indeed a "bunker"for dormant I wrote an email to Stratton asking him specificallyabout the Wheldon version of his protocal, sinceWheldon's recommendations are a bit different in termsof the ongoing abx. Stratton wrote me back saying thatthe doxy/zithro combo was fine, but the flagyl is thekey. Pretty much a direct quote.Jim