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Re: Re: nature of a herx - BP

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> >  The literature specifically  " The Journal of Antimicrobial

> > Chemotherapy " has shown that the CHOICE of abx can either reduce

> > or increase the amount of endotoxin release as Gneg bacteria die.

I've been on the protocol that is not named here, therefore low dose,

so I don't know if what I'm saying applies in general. What happened to

me is that as soon as I added a tiny amount of Zithromax to 100 mg

Minocin (every other day), I ended up with " perma-herx " . After 3 months

of it, I was sick of it and I said to myself, what can I do that's

useful during the time I am waiting for my ID doc appointment? So I

decided to go back to just Benicar and Minocin, but increase the Mino.

I am now up to 150 mg. every other day and I am getting the type of

herx that I can deal with -- it comes and then goes. I don't know if I

fare as well on Mino without the Benicar or not. All I know is that I

have had improvement on it, and it hasn't been unbearable. Maybe I am

seeing the anti-inflammatory characteristics of Mino.

- Kate D.

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Yes ,makes sense , hyper-coagulation = poor blood supply to tissues which is a triple whammy ...poor supply of oxygen ..Hypoxia.. poor supply of components of our IS...and poor supply of drugs ..end result, bugs have yet another trick to evade destruction...

-----Original Message-----From: infections [mailto:infections ]On Behalf Of penny Sent: 29 April 2005 15:47infections Subject: [infections] Re: nature of a herx - BP"Barb Peck" <egroups1bp@y...> wrote:> I think the blood values would be usefull data in trying to dechiper just what was causing the constant downward trend and increased pain. I think others were trying to figure out the correct panel to baseline in order to yeild usefull data about what the heck is going on." Here's another consideration when taking abx and needing base line markers.I've been hearing recently, from outside sources, that some well versed docs are saying that you can't beat a major infection with an INR above 3.5. That's the maximum clotting time. These docs, who deal with nasty bone infections, are also saying that heparin, nattokinase, lovenox, etc. will not cut it. That they do not maintain consistent INR values. That if you're dealing with a serious infection, you've got to be on lovenox. Possibly for life. :-( The point being that if we've got coagulation disorders, or major coagulation problems (as many of us seem to have), no amount of abx alone is going to rid us of chronic infection. We need serious blood thinning as an adjunct to therapy so we can reach the bugs where they're hiding. And the way to know whether the abx has a chance at working is to have our INR tested weekly while on treatment.penny

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