Re: Heard back from an MS researcher - Rich

[Guest guest]

Rich, you are the greatest! Thanks so much, this one really helped

me get a handle on this issue.

I am starting to see a pattern that COULD effectively relate my

symptoms with brain MRI findings.

There has been a startling loss of brain volume and there are

specific signal abnormalities in the myelin layer. There have been

seizures, hyper-response to low-level stimulus. It begins to appear

as thogh the symptoms are signs of a process that may cumulatively

result in loss of brain tissue.

My seizures have involved lost time. Temporal lobe seizures often

cause one-sided atrophy in the hippocampus, which I have (left side,

same side where most of the migraine / neuropathy / vision problems

are localized).

So no one thinks I'm going off into some sort of delusional

confidence about what glutathione will or won't accomplish, all I am

concluding here is that it is VERY worth trying, as in repeat

treatments over a period of at least a few months. The cost of the

glutathione itself is not prohibitive, but the cost of adminstration

can be. I have GOT to get help in that department, find out whether

a visiting nurse can teach Bob and I how to administer so we can do

it ourselves once my PICC line is in.

So not to worry, no premature surge of hope, just a reasoned

assessment that this is something that should be attempted.

Yay for Rich, yay for me, yay for I & I! I like what we're doing

here.

My case for glutathione treatment is seeming very strong! I learned

yesterday that IV glutathione is a COMMON treatment in my LLMD's

practice - all the more reason to insist. I am working on clarifying

the amount of financial support I can expect from family, and that

has to budgeted between various possible expenses, so I need a level

of information that goes beyond 'such and such might help'. Your

posts, Rich, are so very helpful in that regard.

Bless you!

> > Don't ya love it when you write to these guys and they reply?

I'm

> > not sharing his name, he didn't give me permission and what he

had

> > to say is not so compelling that you need to have the background.

> >

> > But it IS interesting. He had written about how a type of

> glutamate

> > receptor in the brain called " AMPA " contributes to the

destruction

> > of myelin, which is a key finding in MS, a finding in my very

own

> > brain MRI, and possibly a key cause of certain types of

> neurological

> > distress.

> >

> > I wrote him to ask if there were any drugs that blocked these

> > receptors effectively without accompanying toxicity. He wrote me

> > back to say that there are none on the market but are some in

> trials

> > for Parkinson's disease - if they're approved, they will

probably

> be

> > prescribed for MS as well.

> >

> > It's pretty fascinating stuff. the AMPA receptor, triggered by

> > glutamate, apparently contributes to the death of

> oligodendrocytes,

> > which are the cells that myelin grows out of. This is one reason

> why

> > glutamate build up in the brain is bad, and glutamate transport

is

> > is so important.

> >

> > Rich, if you're reading please let me know if I've mangled

> something.

> >

> > Cheers all,

> >

> >