Re: effectiveness of clindamycin for mycoplasma p.s.

[Guest guest]

I think Clindamycin is seen as a good substitute for people who

can't take penicillin. What I've heard, is if you're sensitive to

penicillin, then stick with that.

There's a good argument to be made for trying to get the most out of

the older classes of drugs if they're effective for you. They tend

to be broader spectrum, not to mention WAY cheaper. So there's not

necessarily always a good reason to go for the newer, expensive

designer drug, if an earlier version works. It will also slow the

development of resistance and give you lots more abx options in the

future.

penny

> has anyone had any success or thoughts on clindamycin?...seems i

can't

> take any abx longer than 3 months and then is resistant.

>

> Boy can I relate to that last part.

>

> I don't know, it didn't seem to be effective for me, but I started

out

> so resistant to so many abx, so I'm not the best gauge. To be

honest,

> I've never heard anybody all that excited about clindamycin or of

it

> having anything more than short term effectiveness. It's commonly

> prescribed for dental infections, but like I said, most people I

know

> with dental infections haven't found Clindamycin to really help

that

> much. I'm sure there are exceptions. The people I talk to are all

> pretty sick anyway. What I've actually heard more about it are

> concerns that it can promote the development of other bugs when

used

> longer term. But this is the word on the street. I don't know what

the

> research actually says. I'd look it up if I were you, especially

in

> pub med.

>

> Here's a quote from:

> http://www.netdoctor.co.uk/medicines/100003375.html

>

> " However, it is not a widely used antibiotic because the risk of

> developing antibiotic-associated colitis (inflammation of the

colon)

> is greater with clindamycin compared to other antibiotics. This

> usually results in severe diarrhoea and clindamycin should be

stoppped

> immediately if this occurs. "

>

> I've heard people report this happening to them, so I was cautious

> when I took it. In people like us, this severe diarrhea can be

very

> serious, so if you start having problems with that symptom, you

really

> should heed the warning to stop immediately.

>

> I have a pretty infected/sick friend who's going to try it to see

if

> any of her symptoms are relieved. If the news is positive, I'll

let

> you know.

>

> Personally, I'd be surprised if it ends up being a power abx. But

> stranger things have happened.

>

> penny

>

> p.s. Have you revisited any of your earlier successful abx?

Sometimes

> they become effective again after a good break. There's some

pubmed

> citations to support that some organisms that have become

resistant

> will revert and become sensitive again. You might give it a shot.

For

> instance, I might try Clindamycin now, and it could possibly work.

Who

> knows? Especially if my bacterial balance has shifted, which I'm

sure

> it has. The other thing that most docs tell you is that you need

to do

> more than one abx at a time to effectively fight a serious

infection.