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Re: effectiveness of clindamycin for mycoplasma

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mermsie@a... wrote:

has anyone had any success or thoughts on clindamycin?...seems i can't

take any abx longer than 3 months and then is resistant.

Boy can I relate to that last part.

I don't know, it didn't seem to be effective for me, but I started out

so resistant to so many abx, so I'm not the best gauge. To be honest,

I've never heard anybody all that excited about clindamycin or of it

having anything more than short term effectiveness. It's commonly

prescribed for dental infections, but like I said, most people I know

with dental infections haven't found Clindamycin to really help that

much. I'm sure there are exceptions. The people I talk to are all

pretty sick anyway. What I've actually heard more about it are

concerns that it can promote the development of other bugs when used

longer term. But this is the word on the street. I don't know what the

research actually says. I'd look it up if I were you, especially in

pub med.

Here's a quote from:

http://www.netdoctor.co.uk/medicines/100003375.html

" However, it is not a widely used antibiotic because the risk of

developing antibiotic-associated colitis (inflammation of the colon)

is greater with clindamycin compared to other antibiotics. This

usually results in severe diarrhoea and clindamycin should be stoppped

immediately if this occurs. "

I've heard people report this happening to them, so I was cautious

when I took it. In people like us, this severe diarrhea can be very

serious, so if you start having problems with that symptom, you really

should heed the warning to stop immediately.

I have a pretty infected/sick friend who's going to try it to see if

any of her symptoms are relieved. If the news is positive, I'll let

you know.

Personally, I'd be surprised if it ends up being a power abx. But

stranger things have happened.

penny

p.s. Have you revisited any of your earlier successful abx? Sometimes

they become effective again after a good break. There's some pubmed

citations to support that some organisms that have become resistant

will revert and become sensitive again. You might give it a shot. For

instance, I might try Clindamycin now, and it could possibly work. Who

knows? Especially if my bacterial balance has shifted, which I'm sure

it has. The other thing that most docs tell you is that you need to do

more than one abx at a time to effectively fight a serious infection.

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