Neurosyphilis vs. Neuroborreliosis - 2004 abstract

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Nervenarzt. 2004 Dec 4; [Epub ahead of print] Related Articles,

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[Neurosyphilis and neuroborreliosis Retrospective evaluation of 22

cases.]

[Article in German]

Blatz R, Kuhn HJ, Hermann W, Rytter M, Rodloff AC.

Institut fur Medizinische Mikrobiologie, Universitat Leipzig.

We present laboratory data from 22 patients suspected of having

neurosyphilis. In two cases the suspicion could not be confirmed,

and in 20 cases neurosyphilis was detected. The sera from 17

patients were also assayed for Borrelia-specific antibodies.

Suspicious immunoglobulin G antibody indices were detected in nine

cases and a suspicious immunoglobulin M antibody index in one. In

six of these, stored CSF/serum pairs were available to specify the

antibodies by immunoblotting. This allowed for the identification of

one patient apparently infected by both Borrelia spp. and Treponema

pallidum. In all cases of newly suspected neurosyphilis, we

recommend considering neuroborreliosis at the same time.

PMID: 15580469 [PubMed - as supplied by publisher]