B12 - Methyl or hydroxo? IM or Sub-q?

[Guest guest]

Hi Steve,

What form of B-12 are you using? Are you doing intra-muscular or

subcutaneous injections?

I think Dr. Cheney used hydroxocobalamin, and I think intra-muscular is

usually advised. I found a guy with an interesting website, Jim Neubrander,

M.D., who prefers methylcobalamin and says sub-q works better. Here's what

he wrote:

" For years I have prescribed vitamin B12, administered orally, sublingually,

or by injection. I have used it for a number of disorders, none of which

were autism until 1999. In the past I referred to " B12 " in a generic sense,

assuming that there was no difference clinically between using any of its

three easily available forms: cyanocobalamin, hydroxycobalamin, and

methylcobalamin. Now, four years after beginning to treat autism with " B12 "

I hold a very different view, that view being the methylcobalamin form of

B12 holds the greatest promise for treating children on the autistic

spectrum. "

Neubrander goes into some detail as to why he prefers subcutaneous

injections, not intramuscular injections. A starter quote:

" Initially I used both the intramuscular and/or subcutaneous routes.

However, within 6 to 8 weeks it was my " impression " that I was getting a

higher response rate in the group of children that were using the

subcutaneous route of administration. Hypothetically, subcutaneous

injections may produce a " slow time-release " process, allowing a " leaching

effect " of the methylcobalamin... "

Incidentally, I noticed that Neubrander writes " hydroxy-, " not " hydroxo-, "

so I googled the two spellings. " HydroxOcobalamin " gets 13,000 hits and

" HydroxYcobalamin " gets only 861.

http://www.autisme-montreal.com/congres/2003/Neubrander.html

Sue ,

Upstate New York

[Guest guest]

I tried IM at the beginning, but the shock was too much to cope with,

since then I am taking about 5 mg per day, of methylcobalamin mixed

with some cyanocobalamin. I take 1-mg solution of the latter, that can

be injected or can be taking orally.

It has been a god send.

I cannot talk highly enough of it. The detox is continued. I still feel

a little iffy when taking it but the general improvement is profound.

> Hi Steve,

>

> What form of B-12 are you using?  Are you doing intra-muscular or

> subcutaneous injections?

>

> I think Dr. Cheney used hydroxocobalamin, and I think intra-muscular

> is

> usually advised.  I found a guy with an interesting website, Jim

> Neubrander,

> M.D., who  prefers methylcobalamin and says sub-q works better. 

> Here's what

> he wrote:

>

> " For years I have prescribed vitamin B12, administered orally,

> sublingually,

> or by injection. I have used it for a number of disorders, none of

> which

> were autism until 1999. In the past I referred to " B12 " in a generic

> sense,

> assuming that there was no difference clinically between using any of

> its

> three easily available forms: , hydroxycobalamin, and

> methylcobalamin. Now, four years after beginning to treat autism with

> " B12 "

> I hold a very different view, that view being the methylcobalamin

> form of

> B12 holds the greatest promise for treating children on the autistic

> spectrum. "

>

> Neubrander goes into some detail as to why he prefers subcutaneous

> injections, not intramuscular injections.  A starter quote:

>

> " Initially I used both the intramuscular and/or subcutaneous routes.

> However, within 6 to 8 weeks it was my " impression " that I was

> getting a

> higher response rate in the group of children that were using the

> subcutaneous route of administration. Hypothetically, subcutaneous

> injections may produce a " slow time-release " process, allowing a

> " leaching

> effect " of the methylcobalamin... "

>

> Incidentally, I noticed that Neubrander writes " hydroxy-, " not

> " hydroxo-, "

> so I googled the two spellings.  " HydroxOcobalamin " gets 13,000 hits

> and

> " HydroxYcobalamin " gets only 861.

>

> http://www.autisme-montreal.com/congres/2003/Neubrander.html

>

> Sue ,

> Upstate New York

>

>

>

>

>