Guest guest Posted March 15, 2005 Report Share Posted March 15, 2005 In syphilis as well, there is good evidence for the commonness of sero-negative or quite weakly sero-positive infection. Mattmans book says suggests all the Ab can be tied up in immune complexes (Ab-antigen complexes). She says this at least once without a ref and maybe again with(?) one. I have tried to find where she may(?) give the ref because I'd be very interested in seeing justifications of this idea. It seems likely to me that it would take something quite unusual to cause the body to fail to manufacture Ab to surplus - the price for that failure is too high. The ~1400 pathogens that infect humans all do something quite unusual, or they wouldnt be able to overcome our superb immunity. Still I'm skeptical of the immune complex theory. If the immune complexes are present in serum it may be possible to test the theory because there have now been developed techs which can dissociate at least some Ab-antigen complexes. Cant remember where I read about that. Quote Link to comment Share on other sites More sharing options...
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