RE : Ploughing rats

[Guest guest]

Dear ,

Weird word for rats !

Can that be a " digging " behaviour, like moles (personality transfer being a

pharmacological or adverse effect of the drug) ?

Or maybe they were just reading Woody Guthrie poems ( " my hoe and my plough is my

gun " ) while receiving the drug ?

I'd ask the client and/or the report author, since understanding of this word

seems to be kind of a guess-type process

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-----Message d'origine-----

De : medical_translation

[mailto:medical_translation ] De la part de Sosnovsky

Envoyé : mercredi 19 décembre 2007 11:18

À : medical_translation

Objet : Ploughing rats

Dear Colleagues,

In a toxicological study report, I have difficulty understanding " ploughing " in

the following context (samples below are taken from different sections):

At 250 mg/kg/day there were limited clinical signs (predominantly salivation

and ***ploughing***), and decreases in body weight gain and food consumption.

At 125 mg/kg/day, the majority of surviving animals exhibited ***ploughing***

and increased salivation.

Clinical observations, confined to repeat-dose animals receiving 200 mg/kg/day,

included a slight decrease in activity, partially/shut eyes and pilo-erection,

***ploughing***, increased salivation, and partial generalised swelling of the

abdomen.

Most probably, this means that rats salivated while ploughing soil or something

in their cages, which is a kind of scent-marking behavior. Perhaps, some other

behavioral response?

Thank you in advance

Best regards,

_________________________

Sosnovsky, M.D.

Biomedical Translation & Editing

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