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Re: fungicides

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david@... wrote:

>Hi all,

>Anybody know of a fungicide for use in soap. We use triclosan,

>triclocarban, salicylic acid, sulfur, benzoic acid, resorcinol. Not

>all at once of course, but these are generally bacteriocides. I see

>athletes foot powders contain tolnaftate, but can't find a supplier,

>nor can find it in INCI literature.

isn't clotrimazole a fungicide? i don't know if this is approved for use in the

UK, or in soaps, but i do know it is approved in the US for use in lotions.

kevin/maurice?

~risa

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>david@... wrote:

>

>>Hi all,

>>Anybody know of a fungicide for use in soap. We use triclosan,

>>triclocarban, salicylic acid, sulfur, benzoic acid, resorcinol. Not

>>all at once of course, but these are generally bacteriocides. I see

>>athletes foot powders contain tolnaftate, but can't find a supplier,

>>nor can find it in INCI literature.

>

>isn't clotrimazole a fungicide? i don't know if this is approved for use in

the UK, or in soaps, but i do know it is approved in the US for use in lotions.

kevin/maurice?

Clotrimazole does appear in the INCI dictionary but according to the

CFR its approved for animals. Says nothing about people. Its activity

may be limited.

21 CFR PART 524

OPHTHALMIC AND TOPICAL DOSAGE FORM NEW ANIMAL DRUGS

(a) Specifications. Each gram of cream contains 10 milligrams of

clotrimazole.

(B) Sponsor. See 000859 in Sec. 510.600©.

© Conditions of use

(1) Amount. Apply \1/4\-inch ribbon of cream per square inch of lesion

once daily for 2 to 4 weeks.

(2) Indications of use. For the treatment of fungal infections of dogs

and cats caused by Microsporum canis and Trichophyton mentagrophytes.

(3) Limitations. Wash hands thoroughly after use to avoid spread of

infection. Federal law restricts this drug to use by or on the order of

a licensed veterinarian.

Maurice

------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

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On Wed, 06 Jun 2001 21:18:13 -0000, david@...

wrote:

>

>Hi all,

>Anybody know of a fungicide for use in soap. We use triclosan,

>triclocarban, salicylic acid, sulfur, benzoic acid, resorcinol. Not

>all at once of course, but these are generally bacteriocides. I see

>athletes foot powders contain tolnaftate, but can't find a supplier,

>nor can find it in INCI literature.

>Any ideas would be welcome.

Dave,

Try

http://www.sourcerer.co.uk/chempages/2219500P.HTM

and

http://www.upltd.com/index.html

Maurice

------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

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Hi Dave

Are you looking for an antifungal preservative or for an antifungal agent to

be applied topically? If the second, then whatever you use will be virtually

ineffective in a wash off product, much as foot powders are, for that matter!

Can't help with the first...

Benzoic acid is quite effective against tinea, as is salicylic acid.

Clotrimazole, and the other imidazoles (econazole, miconazole and

sulcanazole) are as well, and are also used for candidiasis. Tolnaftate and

the undecenoates are often used for athletes foot, but probably are not so

effective. Nystatin is effective against candidiasis, but not not against

tineas.

What about neem? There should be some good supporting literature about it

somewhere...

Rose

The London soap Company

In a message dated 7/6/01 9:49:43 am, Cosmeticinfo writes:

<<Hi all,

Anybody know of a fungicide for use in soap. We use triclosan,

triclocarban, salicylic acid, sulfur, benzoic acid, resorcinol. Not

all at once of course, but these are generally bacteriocides. I see

athletes foot powders contain tolnaftate, but can't find a supplier,

nor can find it in INCI literature.

Any ideas would be welcome.

Dave E

>>

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Thanks for that Rose, and Maurice and Risa also.

I realise fungicides tend to need a long application time, and will

make it well aware to the customer. I have made a 1% sulfur/1%

salicylic acid soap, and a 0.1% benzoic acid/0.2% salicylic acid soap

at the request of the customer. Might suggest Neem, I have a bottle

of that somewhere.

Regards

Dave E

> Hi Dave

> Are you looking for an antifungal preservative or for an antifungal

agent to

> be applied topically? If the second, then whatever you use will be

virtually

> ineffective in a wash off product, much as foot powders are, for

that matter!

> Can't help with the first...

>

> Benzoic acid is quite effective against tinea, as is salicylic

acid.

> Clotrimazole, and the other imidazoles (econazole, miconazole and

> sulcanazole) are as well, and are also used for candidiasis.

Tolnaftate and

> the undecenoates are often used for athletes foot, but probably are

not so

> effective. Nystatin is effective against candidiasis, but not not

against

> tineas.

>

> What about neem? There should be some good supporting literature

about it

> somewhere...

> Rose

> The London soap Company

>

> In a message dated 7/6/01 9:49:43 am, Cosmeticinfo@y... writes:

>

> <<Hi all,

> Anybody know of a fungicide for use in soap. We use triclosan,

> triclocarban, salicylic acid, sulfur, benzoic acid, resorcinol. Not

> all at once of course, but these are generally bacteriocides. I see

> athletes foot powders contain tolnaftate, but can't find a

supplier,

> nor can find it in INCI literature.

> Any ideas would be welcome.

>

> Dave E

> >>

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