Guest guest Posted October 24, 2007 Report Share Posted October 24, 2007 You know, I wish I had been trying to learn all this stuff when my mind was working at full capacity. When a biopsy is taken from inside the body such as when it is done during other surgery, is it always a wedge biopsy? Jan H > > I think some are confusing the progression of liver disease which has > three stages with liver biopsy readings which also has different > stages for inflammation, fibrosis, cirrhosis. Different pathologists > may also give different biopsy readings. Also, a 1 " needle biopsy may > have different results than a wedge biopsy. > > Liver Disease progresses in the following stages. > Inflammation (regardless of the cause, I.e, NASH, NALD or alcohol). > This is also called hepatitis especially when the cause is undetermined. > Then Fibrosis and unless treated or the progression stopped can lead > to cirrhosis. > http://www.liverfoundation.org/education/info/progression/ > http://www.emedicine.com/med/topic3183.htm > > A biopsy reading will show inflammation, necrosis, fibrosis etc. > Grading and Staging of hepatitis by assigning scores for severity are > helpful in managing patients with chronic hepatitis. The degree of > inflammation and necrosis can be assessed as none, minimal, mild, > moderate, or severe. > The degree of fibrosis can be similarly assessed. Scoring systems are > particularly helpful in clinical studies on chronic hepatitis. > > So grades and staging may also be labeled differently from hospital to > hospital. So you may have severe inflammation with slow or minimal > progression based on the type of fibrosis. Like fibrosis without bridging. > > http://www.hcvets.com/data/hcv_liver/liver_biopsy.htm > http://www.emedicine.com/med/topic2969.htm > > MaC > > > -- Jan H Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 24, 2007 Report Share Posted October 24, 2007 Where does the doctor get this number from anyway.. I have my biopsy report and all I remember it saying is Cirrhosis, with bridging fibrosis. Does that alone determine the stage or grade, or is it also determined by liver function, portal hypertention, ascites.. etc.. Who assigns this number.. I dont believe it on my biopsy report but I will find it and read it later.. Debra > > I think some are confusing the progression of liver disease which has > three stages with liver biopsy readings which also has different > stages for inflammation, fibrosis, cirrhosis. Different pathologists > may also give different biopsy readings. Also, a 1 " needle biopsy may > have different results than a wedge biopsy. > > Liver Disease progresses in the following stages. > Inflammation (regardless of the cause, I.e, NASH, NALD or alcohol). > This is also called hepatitis especially when the cause is undetermined. > Then Fibrosis and unless treated or the progression stopped can lead > to cirrhosis. > http://www.liverfoundation.org/education/info/progression/ > http://www.emedicine.com/med/topic3183.htm > > A biopsy reading will show inflammation, necrosis, fibrosis etc. > Grading and Staging of hepatitis by assigning scores for severity are > helpful in managing patients with chronic hepatitis. The degree of > inflammation and necrosis can be assessed as none, minimal, mild, > moderate, or severe. > The degree of fibrosis can be similarly assessed. Scoring systems are > particularly helpful in clinical studies on chronic hepatitis. > > So grades and staging may also be labeled differently from hospital to > hospital. So you may have severe inflammation with slow or minimal > progression based on the type of fibrosis. Like fibrosis without bridging. > > http://www.hcvets.com/data/hcv_liver/liver_biopsy.htm > http://www.emedicine.com/med/topic2969.htm > > MaC > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted October 24, 2007 Report Share Posted October 24, 2007 Good question! I'll find out and post the different biopsies. Although in the meantime, check the biopsy links below it may explain further there. MaC Jan Holman wrote: You know, I wish I had been trying to learn all this stuff when my mind was working at full capacity. When a biopsy is taken from inside the body such as when it is done during other surgery, is it always a wedge biopsy? Jan H > > I think some are confusing the progression of liver disease which has > three stages with liver biopsy readings which also has different > stages for inflammation, fibrosis, cirrhosis. Different pathologists > may also give different biopsy readings. Also, a 1 " needle biopsy may > have different results than a wedge biopsy. > > Liver Disease progresses in the following stages. > Inflammation (regardless of the cause, I.e, NASH, NALD or alcohol). > This is also called hepatitis especially when the cause is undetermined. > Then Fibrosis and unless treated or the progression stopped can lead > to cirrhosis. > http://www.liverfoundation.org/education/info/progression/ > http://www.emedicine.com/med/topic3183.htm > > A biopsy reading will show inflammation, necrosis, fibrosis etc. > Grading and Staging of hepatitis by assigning scores for severity are > helpful in managing patients with chronic hepatitis. The degree of > inflammation and necrosis can be assessed as none, minimal, mild, > moderate, or severe. > The degree of fibrosis can be similarly assessed. Scoring systems are > particularly helpful in clinical studies on chronic hepatitis. > > So grades and staging may also be labeled differently from hospital to > hospital. So you may have severe inflammation with slow or minimal > progression based on the type of fibrosis. Like fibrosis without bridging. > > http://www.hcvets.com/data/hcv_liver/liver_biopsy.htm > http://www.emedicine.com/med/topic2969.htm > > MaC > __________________________________________________ Quote Link to comment Share on other sites More sharing options...
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