Guest guest Posted March 23, 2005 Report Share Posted March 23, 2005 Hi Annette, I've encounterd similar only once in patient who developed an allergic reaction to drugs he was taking. Diagnosis of Henoch-Schonlein purpura was later confirmed by Consultant on testing as showed typical vaculitis. Patient was taking phenytoin and prednisalone and it was concluded, by the consultant that the combination of the two was the cause. The steroids were withdrawn and the situation resolved. The H/S generally resolves after about 4 weeks but may recur after an interval of several weeks. Steroids alone can cause purpurea. Hope this is of some help. Allshorn purpura Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2005 Report Share Posted March 23, 2005 dear annette from experiance i have found that anyone on steroids has a greater tendency to bleeding and bruising especially during venepuncture regardless of how small a dose. linda palmer purpura > > dear all > can anyone offer any insight into the following? > i have been treating a patient with auto immune hepatitis for about 7 years.He is at present on 3 mg prednisolone plus a bile acid and didronel as well as an epo/clo supplement.He has been very well -all liver function tests have been stable for quite a long time. > however over the winter he had quite a bad chest infection for which he was Rx ab s.He was left feeling very fatigued for quite a number of weeks after and he noticed he was getting spontaneous bleeds under the skin.He had a blood test done which left the whole of his forearm bruised and can wake up with a black eye.All blood/biochemistry tests have come back as normal.He has an appointment with his liver conultant next week and was wondering if there was any thing in his mix that could be causing the bleeding. > I give him milk thistle seed powder plus a mix of the following powders :glycyrrhiza , berb vulg , foeniculum , curcuma , zingiber , chomomilla and eleuthero all of which he has been on for about 6-7 years.are there long term implications in any of these herbs do you think.Obvioulsy Im concerned about the possible interaction between the glycyrrhiza and prednisolone but it was only by adding this that he could maintain such a low steroid dose. > the bnf states rare blood dyscrasias with didronol ( pancytopenia , leucopenia ..) but his bloods have come back normal.the consultant doesnt think the low dose of steroids could be the culprit. > any ideas?sorry about the length of this query.thanks in anticipatiion , > annette > > > Quote Link to comment Share on other sites More sharing options...
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