Guest guest Posted July 13, 2005 Report Share Posted July 13, 2005 This sounds to me a good example of the endobiogenic principle (of French physicians Duraffourd and Lapraz). Think of the Hypothalamus as the " Manager " of the system - or, literally, the nerve centre. All hormones exist by virtue of feedback mechanisms within the loosley defined neuro-endocrine system. Neuropeptides seem to have some of the most intricate systemic effects. (Some are found in such diverse places as the gut and the brain). All local effects eventually have systemic effects, and vice versa. This is not always obvious and it is nearly always difficult to understand but its a tremendous way to understand the aetiology of all health and disease. Wish someone would produce some neuro-endocrine metabolic pathways; lind Blackwell made a start - any news Ros ? Chenery www.rutlandbio.com mirena and vitex > Hi ) > > My enquiry regards a client I have been treating this past 9 months > primarily for PMS, with a bit of anxiety and mild depression too. > Investigations within the past few months have revealed fibroids and she > has > recently received (for want of a better word) a mirena progestogen > secreting/releasing coil/IUD. One of my approaches to the PMS she > experiences has been vitex agnus-castus. I'm/we're wondering whether the > progestogen coil will interfere with/overshadow the vitex. I'm very aware > that conventional prescription hormones tend to overrule the hormonal > effects of anything else. technically this coil is supposed to have local > effects, not systemic ones. My client did however experience quite some > systemic hormonal effects following the introduction of the coil. Do any > of > you have nay experience of or thoughts on this type of situation? All > appreciated. > > Regards, > eirwen > Enfield. > > > > > List Owner > > > > Graham White, MNIMH > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 13, 2005 Report Share Posted July 13, 2005 Dear Eirwen, Number of patients I've seen using this coil have had problems, and they weren't just local. Also these were women who had not had problems before the coil was fitted. I have to admit one was incensed when she discovered it had the hormone as well, she hadn't been told and couldn't understand why she felt so awful. Once it was removed she was fine again. Allshorn mirena and vitex Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2005 Report Share Posted July 15, 2005 > paul wrote: > > This sounds to me a good example of the endobiogenic principle (of French > physicians Duraffourd and Lapraz). [snip] Hi paul, thanks for your response and thoughts - the endobiogenic principle sounds fascinating and I'm away to do a bit more reading about it. but the upshot of it (and from susan's email) is that my client is not going to be able to escape systemic effects from this 'local' treatment *sigh* Best regards, eirwen. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2005 Report Share Posted July 15, 2005 > Allshorn wrote: > Dear Eirwen, Number of patients I've seen using this coil have had > problems, [snip] hi susan, thanks for your response... even though it suggests that my client will not be able to escape systemic effects from this 'local' treatment *unsmile* It's reassuring to know that in your clients' case(s) problems settled once the coil was removed. Bit of a bummer here as we'd got the PMS symptoms largely sorted, and it sounds like this treatment may upset the cycle again... and I probably need to re-evaluate the usefulness/effectiveness of vitex. Best regards, eirwen. Quote Link to comment Share on other sites More sharing options...
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