Persistent SD after taking venlafaxine

[Guest guest]

Hi all

Seven years ago I was diagnosed as having Major Depressive Disorder

and been taking paroxetine (20 mg and then 30 mg) ever since. It never caused SD

or any other problems. Eight months ago my depression got worse and my

psychiatrist added venlafaxine (initially 75 mg and gradually up to 225 mg). My

libido decreased slowly and 4 months later

I realized my libido was almost non-existent and that I have erectile

dysfunction. I discovered this as my new girlfriend and I were getting

intimate and I simply panicked and stopped both my medications abruptly.

Needless to say, I suffered from anxiety and depression and my life became a

living nightmare, so I resumed paroxetine 20 mg but never touched venlafaxine

ever since. When two months elapsed and the SD

persisted I stopped taking paroxetine too. It's been 4 months now

and I still have SD. Viagra doesn't work for me and it seems I will

have to try intracavernous injections (ouch) until I find something

that works.

What are the chances that the SD will ever stop?

[Guest guest]

Hi yossibensheetrit,

sounds nearly like my medication in the past. I was over years on paroxetin and

clonazepam first. nothing negative. but i was 20 - the hormones were maybe hight

enough?

than a new doctor in a new town wouldn't give me clonazepam anymore - but the

first one made me addicted. than could not find sleep anymore and stopped also

paroxetin. it was horrible. i got doxepin later. but than i was tired the hole

day. i stopped everything and than my life was hard and i had trouble with

sleep. but with my fantastic girl friend it was possible.

after a while my depression came back were strong, i couldn't find an minute of

sleep and nothing helped. not lorazepam, not zopiclon, no tricyclic. it was also

something with my girlfriend.

i came in psychiatric hospital and after al while they took me on venlafaxine.

it worked wonders for me, maybe bcause i got metoprolol too and both were

destroyed by the same cyp : cyp2d6.

one time i had a serotonin syndrome. crazy thing.

with venlafaxin my libido wasn't anymore existent after awhile, but i thought i

cannot stop it. that would be my death. but my girl friend went away. i wasn't

able to feel anything about it. i cannot feel anything if somebody of my family

would die!

that is so terrible. no normal person can understand that. that is pssd too.

i went awaz from venlafaxine as i get something like heart attacks, difficulty

to breathing - hard to explain - pulmonary hypertension maybe. it went away

after i stopped the medizine. dicontinuing venla. was the worst experience of my

hole life.

?hm?

i think i post this in the false thread. i wouldn't write so much that it is

now.

to your question: i think there is hope in anything that raise dopamine

(especially activate D2 and D3 receptors and NOT D1) acetylcholine (especially

M3 and lesser nicotinic receptors) and maybe histamine (h2-receptors). also

5-ht-antagonists can improve the problem.

to give the brain and body much time is maybe an opinion too.

avoid all antichoninergic, antidopaminergic, gaba-ergic, serotonergic,

antihistaminergic medizine if possible.

i read here about the chance with ginkgo. maybe it is a chance?!

(if my english is hard to read - sorry. my native language is german.)

>

> Hi all

>

> Seven years ago I was diagnosed as having Major Depressive Disorder

> and been taking paroxetine (20 mg and then 30 mg) ever since. It never caused

SD or any other problems. Eight months ago my depression got worse and my

psychiatrist added venlafaxine (initially 75 mg and gradually up to 225 mg). My

libido decreased slowly and 4 months later

> I realized my libido was almost non-existent and that I have erectile

> dysfunction. I discovered this as my new girlfriend and I were getting

> intimate and I simply panicked and stopped both my medications abruptly.

> Needless to say, I suffered from anxiety and depression and my life became a

living nightmare, so I resumed paroxetine 20 mg but never touched venlafaxine

ever since. When two months elapsed and the SD

> persisted I stopped taking paroxetine too. It's been 4 months now

> and I still have SD. Viagra doesn't work for me and it seems I will

> have to try intracavernous injections (ouch) until I find something

> that works.

>

> What are the chances that the SD will ever stop?

>