Veritox Newest Power Point Presentation

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Post: Veritox Newest Power Point Presentation

Posted by Sharon Kramer on 11/19/06

http://toxlaw.com/chatboards/blackmold/topic902/11.19.06.20.46.45.htm

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Construction Solutions Conference - Seattle Oct 2006

http://www.constructionsolutionsconference.com/seattle/downl

oads/2006/bryan_hardin.pdf

" Was the dose adequate to produce the specific health

effect? "

Pg 25 " Assume a high airborne concentration of spores

(200,000 spore/m3 " [not mycotoxins]

" How does the calculated maximum dose of the mycotoxin

fumitremorgen compare the lowest dose which causes an

effect in animals? "

[Hard to say when:

1. We have no measurement of mycotoxins in this equation,

only generic " spores "

2. There has been no established number for the amount of

mycotoxins produced by a single spore, particularly when

all types of spores are different.

3. One cannot take animal, or in this case a rodent data

and directly extrapolate a number that is indicative of

human exposure.

4. When humans are exposed to mycotoxins within a moldie

indoor environment, the toxins enter the body via

inhalation, ingestion and dermal contact for varying

periods of time.

5. Therefore, one cannot take an acute inhalation study of

rats, directly corrolate extrapolations and determine

anything one way or the other regarding the establishment

of dose necessary before human symptoms occurs.

6. Nor can one scientifically take the information provided

within this power point and determine anything about

threshold levels of exposure to mycotoxins within an indoor

environment.]

Pg 27 " In a typical mold-contaminated office or residential

environment, it is virtually impossible to inhale

sufficient mycotoxin to cause an adverse effect. "

[There is no scientific foundation to support the above

statement. In addition the information is irrelevant in

understanding human toxicity as it does not address the

other routes of human exposure that simultaneously occur

within a damp indoor environment.]

Pg 28, American College of Occupational and Environmental

Medicine (ACOEM) Council on Scientific Affairs. 2003.

Evidence-Based Statement. Adverse Human Health Effects

Associated with Molds in the Indoor Environment. J

Occupational and Environmental Medicine, 45(5):470-478.

Pg 29 " Current scientific evidence does not support the

proposition that human health has been adversely affected

by inhaled mycotoxins in home, school, or office

environments.

& #56256; & #56510;Except for persons with severely impaired immune systems,

indoor mold is not a source of fungal infections. "

[These two above statements are incorrect and not founded

upon any scientific study. Much current scientific evidence

supports adverse human health effects from the matter. The

body of evidence is growing daily. The term " inhaled " is

irrelevant and the data to support their " inhaled " theory

is not scientific in foundation to make the conclusions it

does. Current scientific evidence does not support the

proposition that one can take the data used within the

American College of Occupational and Environmental Medicine

paper to form any conclusion of human illness or lack there

of.]

Pg 30 " Institute Of Medicine. 2004. Damp Indoor Spaces and

Health. National Academies Press, Washington, D.C. "

[The Institute of Medicine report directly contradicts all

the above statements made within this power point and the

methods used to support these statements within the

American College of Occupational and Environmental Medicine

paper:

IOM Executive Summary:

" Toxicologic studies, which examine such responses using

animal and cellular models, cannot be used by themselves to

draw conclusions about human health effects. "

IOM Chapter 4 Mycotoxins

Summary:

" Except for a few studies on cancer, toxicologic studies of

mycotoxins are acute or short-term studies that use high

exposure concentrations to reveal immediate effects in

small populations of animals. Chronic studies that use

lower exposure concentrations and approximate human

exposure more closely have not been done except for a small

number of cancer studies. "

IOM Chapter 4 Mycotoxins

Summary

Considerations in Evaluation of Evidence

" Most of the information reviewed in this chapter is

derived from studies in vitro (that is studies in an

artificial environment, such as a test tube or a culture

medium) or animal studies. In vitro studies, as explained

below, are not suitable for human risk assessment. Risk can

be extrapolated from animal studies to human health effects

only if chronic animal exposures have produced sufficient

information to establish no-observed-adverse-effect levels

(NOAELs) and lowest-observed-adverse-effect levels

(LOAELs). Extrapolation of risk exposure from animal

experiments must always take into account species

differences between animals and humans, sensitivities of

vulnerable human populations, and gaps in animal data. " ]

Pg 34, " AAAAI: Position Paper

Bush RK, et al.The medical effects of mold exposure.

(Position paper of the American Academy of Allergy, Asthma,

and Immunology.) Journal of Allergy and Clinical

Immunology, 117(2):326-333. "

Pg 38 " We agree with the American College of Occupational

and Environmental Medicine evidence-based statement and the

Institute of Medicine draft, which conclude that the

evidence does not support the contention that mycotoxin-

mediated disease (mycotoxicosis) occurs through inhalation

in nonoccupational settings. "

[This is not a scientific statement when the American

College of Occupational and Environmental Medicine, and the

Institute of Medicine Draft, directly contradict each

other on this point.]

Pg 39 " The occurrence of mold-related irritant reactions

from exposure to fungal irritants in nonoccupational

settings are theoretically possible, although unlikely to

occur in the general population given exposure and dose

considerations. "

[Again, unscientific. There is no exposure or dose

consideration established to make the determination

of " unlikely " .]

They need a new schtick!

Sharon