Guest guest Posted August 28, 2004 Report Share Posted August 28, 2004 Is there still a risk of yeast with the transdermal and/or IV NAC? Thanks, Cece amino acids and the gut > > > > Just wondering if anyone out there has experienced gut bugs due to > > amino acid supplements? > > We're giving the custom amino acid supplement from Metabolic Maint. > > and have made a lot of changes over the past couple of months based > > on testing. The things I'm targeting as the culprit are: amino > > acids, acetyl-l-carnitine (carnitine in the past has messed him up), > > NAC, too much vitamin C (been giving 500mg time released buffered C > > 2x a day), extra arginine and lysine. > > > > It could be gut bugs from the amino acids OR I'm wondering if the > > amino acids are stressing urea cycle issues and making it hard for > > him to manage the nitrogen load. Or it could be the 5HTP that's in > > his custom amino supplement is messing with his > > serotonin/neurotransmitter balance???? > > At first he did pretty well, but his gut has gotten a bit out of wack > > and behaviorally he's had a backslide -- he's becoming rigid, very > > obsessive, and emotional/tempermental. > > I've been really ramping up the gut bug treatments and probiotics, > > but it's not helping. His bm's sometimes smell like ammonia (they > > did when on carnitine in past also). > > > > Should I drop all of the suspected things one at a time, or all at > > once and then concentrate on getting the gut back in check and add > > back the stuff one at a time? > > > > What do you guys think? Dr. McCandless, could it be the 5htp in the > > custom amino mix? Jack has been doing great stuff, but now the > > obsessions are getting completely out of hand (numbers, lining up his > > trains, coloring a blank piece of paper with a little of every color > > instead of drawing a picture etc.). > > > > Thanks for any help/opinions on this. > > Sharon Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2004 Report Share Posted August 28, 2004 No, it has to be in the gut to cause the pathogen stimulation. Dr. JM amino acids and the gut > > > > > > > Just wondering if anyone out there has experienced gut bugs due to > > > amino acid supplements? > > > We're giving the custom amino acid supplement from Metabolic Maint. > > > and have made a lot of changes over the past couple of months based > > > on testing. The things I'm targeting as the culprit are: amino > > > acids, acetyl-l-carnitine (carnitine in the past has messed him up), > > > NAC, too much vitamin C (been giving 500mg time released buffered C > > > 2x a day), extra arginine and lysine. > > > > > > It could be gut bugs from the amino acids OR I'm wondering if the > > > amino acids are stressing urea cycle issues and making it hard for > > > him to manage the nitrogen load. Or it could be the 5HTP that's in > > > his custom amino supplement is messing with his > > > serotonin/neurotransmitter balance???? > > > At first he did pretty well, but his gut has gotten a bit out of wack > > > and behaviorally he's had a backslide -- he's becoming rigid, very > > > obsessive, and emotional/tempermental. > > > I've been really ramping up the gut bug treatments and probiotics, > > > but it's not helping. His bm's sometimes smell like ammonia (they > > > did when on carnitine in past also). > > > > > > Should I drop all of the suspected things one at a time, or all at > > > once and then concentrate on getting the gut back in check and add > > > back the stuff one at a time? > > > > > > What do you guys think? Dr. McCandless, could it be the 5htp in the > > > custom amino mix? Jack has been doing great stuff, but now the > > > obsessions are getting completely out of hand (numbers, lining up his > > > trains, coloring a blank piece of paper with a little of every color > > > instead of drawing a picture etc.). > > > > > > Thanks for any help/opinions on this. > > > Sharon > > > > > > Many frequently asked questions and answers can be found at <http://forums.autism-rxguidebook.com> > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted August 28, 2004 Report Share Posted August 28, 2004 Leah, I am very eager to try to pin down what is different about the children who have the adverse response to NAC versus those who don't. Please consider coming over to sulfurstories to talk about what things you've learned about your child's chemistry in other areas. The more details the better the chance of finding the common thread. Sulfurstories was set up as a place to discover the common turf in people with adverse responses to specific sulfur supplements. Encourage others who have had this response to NAC to come talk about it, too! I know we will learn if we can just compare notes well enough. Since I've studied a lot about NAC's role in the body and its trafficking, there is a lot of context (besides gut bugs) that might be relevant. NAC is most helpful to those who have problems with breaking down glutathione at the cell surface. For them, NAC provides a way to get cysteine in the cell by a different route. Sharon, if you are smelling ammonia, then you are probably seeing a stepped up glutaminase chemistry, but why? Is there a reason he might be experiencing acidosis? Have you tried alka seltzer gold? You might see if some people where you live could go in with you to buy a bottle of Bayer's Multistix 10, which measures ten important things in urine which might point to a temporary metabolic dysregulation. MULTISTIX® 10SG Reagent Strips Urine testing strips for glucose, bilirubin, ketones, specific gravity, blood, pH, protein, urobilinogen, nitrate and leukocytes. : 100 strips/box This might allow you to spot something that is changing in good days vs. bad days,. It yields a lot of information for about the cost of a coke for each testing strip. Do you suppose he might be having trouble with acetylated compounds in general since both the NAC and carnitine were acetylated? , listowner of Sulfurstories At 05:16 AM 8/27/2004 +0000, you wrote: >Hi Sharon, > >Has your son taken NAC previously? Did he do o.k. with it? My sons (6 >yr old twins) completely " check out " when given NAC. They are pretty >connected/aware, some spontanous speech, good receptive, generally >happy and fairly easy going but when they had two doses of NAC they >were gone, unreachable, very scripted, very stimmy, very rigid. I've >tried this a few times over the past two years at a low dose and it >happens every time. It generally takes a few days for them to bounce >back. I've read that NAC can be really helpful but in CSB, Dr. McC >explains that some kids just cannot handle it. > >I've also read some posts from parents on another list that NAC can >feed yeast. I think Dr. McC may have mentioned this recently also. > >Just some thoughts... > >Take care, >Leah Maloney > > > > > > > Just wondering if anyone out there has experienced gut bugs due to > > amino acid supplements? > > We're giving the custom amino acid supplement from Metabolic Maint. > > and have made a lot of changes over the past couple of months based > > on testing. The things I'm targeting as the culprit are: amino > > acids, acetyl-l-carnitine (carnitine in the past has messed him >up), > > NAC, too much vitamin C (been giving 500mg time released buffered C > > 2x a day), extra arginine and lysine. > > > > It could be gut bugs from the amino acids OR I'm wondering if the > > amino acids are stressing urea cycle issues and making it hard for > > him to manage the nitrogen load. Or it could be the 5HTP that's in > > his custom amino supplement is messing with his > > serotonin/neurotransmitter balance???? > > At first he did pretty well, but his gut has gotten a bit out of >wack > > and behaviorally he's had a backslide -- he's becoming rigid, very > > obsessive, and emotional/tempermental. > > I've been really ramping up the gut bug treatments and probiotics, > > but it's not helping. His bm's sometimes smell like ammonia (they > > did when on carnitine in past also). > > > > Should I drop all of the suspected things one at a time, or all at > > once and then concentrate on getting the gut back in check and add > > back the stuff one at a time? > > > > What do you guys think? Dr. McCandless, could it be the 5htp in >the > > custom amino mix? Jack has been doing great stuff, but now the > > obsessions are getting completely out of hand (numbers, lining up >his > > trains, coloring a blank piece of paper with a little of every >color > > instead of drawing a picture etc.). > > > > Thanks for any help/opinions on this. > > Sharon > > > > >Many frequently asked questions and answers can be found at ><http://forums.autism-rxguidebook.com> > Quote Link to comment Share on other sites More sharing options...
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