Re: Former MDMA user offers medication advice!

[Guest guest]

Yes interesting theory in relation to the link between the intestine and the

brain. It must be why my acupuncturist is so keen on clearing out my system

first and placing the needles in that area in order to help restore sexual

function. I guess there is also colon irrigation to consider also as a way of

clearing the intestines.

What gets me is the head pressure. I wonder if the same thing I'm experiencing

is happening to others when they say head pressure. Every now again I get a

tingling sensation like there is actually flow occurring inside my brain where

usually my head feels stiff as if made from brick like a tight band is confining

my brain and restricting it. It use to be felt more in the pre-frontal cortex

but now it's more felt at the back of my head and at the sides. Sometimes during

the day I don't feel any stiffness at all and when I'm stressed it gets worst,

could that be what you're saying in relation to abnormal rise in cortisol levels

as a cause to this? I also I never sweat now unless I run like a dog during

exercise. I would like to know if this is typical head pressure symptoms and if

they subside as it's very annoying.

As for the piracetam it sounds very interesting. I heard about it a while a go

on nootropic forum where it was said to improve blood flow and communication

within the brain along with activating the neurotransmiter Muscarinic-

acetyl-cholin to improve memory, abstract thinking and concentration.

I never heard it improving sex function until now which has gotten me curious

enough to purchase some which I just received. I also hear that Picamilon is

just as effective and some have even implemented them both together to get

effects from these nootropics.

At the moment I'm seeing an acupuncturist that specialises in treating sex

dysfunction and have felt heat travel up my spine as an early effect just after

a second treatment. So I will wait to see if this works before trying the

nootropics route, the only downside is it sounds as if it is just a patch rather

than a complete remedy to our problems but in the mean time it would be good for

a lot of us to experience a temporary window of relief just to know what it's

like to feel normal again.

I'm so fed up not just with the sexual dysfunction but with the lack of emotions

where I find it impossible to cry. Do you think that may be the result of an

circuit disconnect with the limbic system in the brain that is the cause of

this? I know you said you have crying spells but what's your view on this?

>

>

>

> Subject: Re: Former MDMA user offers medication advice!

> To: SSRIsex

> Date: Monday, March 21, 2011, 9:54 PM

>

>

>  

>

>

>

> Ben,

>

> I would expect you will start feeling something within an hour or two.

> If not, wait until you take another dose tonight.

> If you have eaten heavy meals in the last few days, that may delay the

process.

>

> It might take you several days, or weeks, according to some reports.

> But I always notice something very quickly. One of the first symptoms is color

seem to be a little brighter, like my eyes suddenly became more acute. I also

see textures, like freckles on my wife's face or fibers in the carpet, much more

clearly. Keep in mind that MDMA is known to cause serotonergic damage in the

visual cortex...

>

> The second symptom I get is a watering mouth. My saliva becomes much more

abundant and more acidic in flavor.

> Let us know how it works out for you, ok?

>

> ,

>

> Why do I stop taking it?

> I believe I answered that pretty clearly in one of my emails.

> The stimulation that the piracetam brings on is quite welcome, for a few

weeks. Then the stimulation seems to be a little unpleasant....sometimes I get

very mild headaches or irritability.

>

> I take my piracetam with fish oil, but I have noticed myself slipping a little

and forgetting the fish oil as I progress. I also think I need to take choline,

which is exhausted by the medication. I will use the choline on my next cycle.

>

> Also, my recovery process seems to be happening in waves. Regardless of the

piracteam, I have noticed that I go through LONG periods of feeling poorly

followed by BRIEF periods of feeling great. When this began it was a very quick

back and forth process. Then it became stretched out, until now my anxiety is

quite mild but it lasts more than a week before I get a real break from it.

Sometimes it feels like is at low levels for 2 weeks. It is less well defined

than it was before.

>

> Look up 'healing plateau'. Once I reach a plateau I feel great, for a little

while. Then the next wave of anxiety begins, and each time the anxiety is a

little easier to tolerate, but it lasts LONGER.

>

> Those with major brain injury likely do not cycle on and off the medication.

But I do it out of instinct, I guess. Not only do I feel like it is time to stop

because of the over-stimulation....I can tell that if I quit.....as the

stimulation tapers off I will start to feel EVEN better, at least for a few

days.

>

> There is a motivation to taper off, then. I have trained myself to expect the

upswing that happens shortly after I stop the medication. Also, I noticed after

my last cycle, that on my first day back on the piracetam I felt AMAZING.

>

> Here is my theory:

>

> Before the piracetam is introduced, the brain is working all on its own trying

to re-wire the intestines into brain matter. As food and acidic enzymes brush up

against the villi and microvilli in your intestines, this causes an irritation

of the serotonin nerves in the gut. They begin to antagonize the sections of the

brain that those nerves are attached to. I believe they are injecting serotonin,

via the spinal cord and brainstem, right into the serotonin network in the base

of the brain. This injection process has been altered, because the network no

longer has enough receptors to receive this fluid. It has to 'drill' some new

receptors, because there is a constant injection of fluid coming from the base

of the brain. As the intestines start to antagonize the brain's serotonin

network, the endocrine system responds. The adrenals release a constant flow of

cortisol.

>

> The cortisol release is quite unpleasant for the owner of the brain. This

causes distress, including increased blood pressure....especially to the regions

of the brain being 'drilled' into! You can feel this increased blood pressure in

your head some days, right? Can you pinpoint which part of the brain is being

targeted on a given day?

>

> Unfortunately, for these new serotonin axons to pop up, it takes a LONG period

of cortisol release. The 'drilling' process is slow. Eventually this process

becomes so distressing that the brain begins to INCREASE its cortisol response

to speed up the process. When this happens, the owner of the brain is more

likely to question whether or not his/her fate is permanent. The areas of the

brain that interpret the passage of time begin telling the owner that this

process may NEVER stop! I have seen this obsessive focus on a 'permanent' state

of suffering in ALL recovering MDMA users. Interestingly, I have also noticed

that my wife goes through a similar process of 'possibly permanent' anxiety when

she is PMSing. Her brain tricks her into focusing on the things in her life that

have been bothering her, and she begins to make statements like, " I can't do

this for another 40 years! " If you didn't know, serotonin is involved in the

cortisol/prolactin release that

> is critical to a woman's cycle. I guarantee that the women in this group

would say their recovery is more difficult during the week leading up to their

period.

>

> One day this cycle of adrenaline and cortisol become SO great that the user

has a freak-out.

> The LIMBIC system has been trying to gain control the whole time, and suddenly

it has success!

> During this period of heightened anxiety a sudden rush of progress is made!

> Only when the brain is convinced that things have gotten worse and will NEVER

get better....do more axons connect to the right pathways! Imagine several

hundred or thousand axons suddenly BLOOM like flowers on a branch!

>

> Once the axons pop up, a healing plateau has been reached. This new storage

capacity for serotonin results in a drop in cortisol and a release of

oxytocin/prolactin. The owner owner feels normal for a few days.

>

> Then the next cycle begins, because the new storage capacity is STILL not

enough to contain the constant flow of serotonin being injected into the base of

the brain.

>

> Now the piracetam is introduced.

> Before it took an extreme amount of cortisol to power this 'drilling' process.

But not anymore.

> The piracetam has increased cellular permeability!

> I believe the first effect of the medication is on the serotonin receptors in

the intestines. Because the receptors in the GUT are more permeable, there is

more bile release and contraction of muscle tissue with LESS irritation of the

villi.

>

> When the seretonin is injected into the base of the brain and begins to flow

down the many branches of the network, the brain tissue is more accepting of

this process. Less cortisol is released, and MORE axons are able to sprout with

a now reduced endocrine response. In fact, I feel that a much GREATER release of

oxytocin/prolactin is allowed from this smaller amount of cortisol. I believe

this is one of the reasons why the first few days on piracetam can be so

emotionally profound for me. The cortisol present generates a sudden rush of

good chemicals (oxytocin, dopamine)

>

> The 'drilling' sensation....the constant 'head pressure'....turns into a

tickling sensation. Sometimes it is a strong tickle, sometimes a weak one. But I

have noticed this on EACH cycle. The difference in sensation is like night and

day. Simultaneously, I feel the 'lump' in my gut has smoothed out. Suddenly the

intestines feel young and responsive again.

>

> Due to the increased permeability, many more axons are able to sprout, but

there is still a 'building up' process. There is still a plateau stage. I

believe it is during the first major plateau that the piracetam becomes

irritating. The brain is ready to relax and enjoy the new progress for a short

period of time, but the continued presence of the drug is encouraging the next

cycle to begin early.

>

> Also, choline is important in regards to cellular permeability. It is one of

the salt ions present in the membrane of the cell. It is also used to synthesize

the neurotransmitter acetylcholine. If piracetam is taking advantage of the

effect of choline on these membranes, then it makes sense that more choline is

needed than normal. Choline supplements have been used in the treatment of

hepatitis, bi-polar disorder, Alzheimer's, and other neurological disorders.

>

> It may be nothing more than a shortage of choline that causes me to stop

taking the Piracetam.

> Maybe it is just reaching a plateau. Maybe it is both.

> Perhaps my 'drilling' and 'tickling' description is nothing more than a crude

metaphor for a very complex process. Maybe I'm way off the mark here....but what

I described is what I have been feeling.

Food...villi....irritation...injection....antagonizing...cortisol....oxytocin...\

..plateau....food....villi....on and on it goes.

>

> The cycle doesn't end....because your GUT is in control, not your brain.

> One day, your gut will stop this drilling process. I don't believe it can go

on forever. Even for those that have been suffering 5-10 years, I bet the

cortisol release has become much more tolerable with time. Faded into the

background.

> There has to be a final plateau...

>

> I hope that ALL of us get there one day. No matter WHERE you fall on the

spectrum, I believe there is still hope.

> Take fish oil, b-vitamins, choline, anti-inflammatory agents.

> Exercise, even if you don't think you can control your muscles at all.

> And yes, try the piracetam.

> But do the rest....I do.

> Who knows if I could report such fast progress if I ONLY took the piracetam.

> I am fighting this as hard as I can. And I find a strange satisfaction in

being able to help others along the way.

>

> Ben, let us know how the piracetam works for you.

> Good luck to all of you.

>

[Guest guest]

Thanks for the explanation. Not sure if many of us here agree with the theory that we have a case of too much dopamine. Many of us get relief from symptoms after using dopamine agonists, which I think is proof that we don't have enough dopamine to begin with. Its only when we increase the dopamine, do we see any improvement.

Subject: Re: Former MDMA user offers medication advice!To: SSRIsex Date: Monday, March 21, 2011, 9:54 PM

Ben,I would expect you will start feeling something within an hour or two. If not, wait until you take another dose tonight. If you have eaten heavy meals in the last few days, that may delay the process.It might take you several days, or weeks, according to some reports.But I always notice something very quickly. One of the first symptoms is color seem to be a little brighter, like my eyes suddenly became more acute. I also see textures, like freckles on my wife's face or fibers in the carpet, much more clearly. Keep in mind that MDMA is known to cause serotonergic damage in the visual cortex...The second symptom I get is a watering mouth. My saliva becomes much more abundant and more acidic in flavor.Let us know how it works out for you, ok?,Why do I stop taking it?I believe I answered that pretty clearly in one of my

emails. The stimulation that the piracetam brings on is quite welcome, for a few weeks. Then the stimulation seems to be a little unpleasant....sometimes I get very mild headaches or irritability. I take my piracetam with fish oil, but I have noticed myself slipping a little and forgetting the fish oil as I progress. I also think I need to take choline, which is exhausted by the medication. I will use the choline on my next cycle.Also, my recovery process seems to be happening in waves. Regardless of the piracteam, I have noticed that I go through LONG periods of feeling poorly followed by BRIEF periods of feeling great. When this began it was a very quick back and forth process. Then it became stretched out, until now my anxiety is quite mild but it lasts more than a week before I get a real break from it. Sometimes it feels like is at low levels for 2 weeks. It is less well defined than it was before.Look up 'healing

plateau'. Once I reach a plateau I feel great, for a little while. Then the next wave of anxiety begins, and each time the anxiety is a little easier to tolerate, but it lasts LONGER. Those with major brain injury likely do not cycle on and off the medication. But I do it out of instinct, I guess. Not only do I feel like it is time to stop because of the over-stimulation....I can tell that if I quit.....as the stimulation tapers off I will start to feel EVEN better, at least for a few days.There is a motivation to taper off, then. I have trained myself to expect the upswing that happens shortly after I stop the medication. Also, I noticed after my last cycle, that on my first day back on the piracetam I felt AMAZING. Here is my theory:Before the piracetam is introduced, the brain is working all on its own trying to re-wire the intestines

into brain matter. As food and acidic enzymes brush up against the villi and microvilli in your intestines, this causes an irritation of the serotonin nerves in the gut. They begin to antagonize the sections of the brain that those nerves are attached to. I believe they are injecting serotonin, via the spinal cord and brainstem, right into the serotonin network in the base of the brain. This injection process has been altered, because the network no longer has enough receptors to receive this fluid. It has to 'drill' some new receptors, because there is a constant injection of fluid coming from the base of the brain. As the intestines start to antagonize the brain's serotonin network, the endocrine system responds. The adrenals release a constant flow of cortisol.The cortisol release is quite unpleasant for the owner of the brain. This causes distress, including increased blood pressure....especially to

the regions of the brain being 'drilled' into! You can feel this increased blood pressure in your head some days, right? Can you pinpoint which part of the brain is being targeted on a given day?Unfortunately, for these new serotonin axons to pop up, it takes a LONG period of cortisol release. The 'drilling' process is slow. Eventually this process becomes so distressing that the brain begins to INCREASE its cortisol response to speed up the process. When this happens, the owner of the brain is more likely to question whether or not his/her fate is permanent. The areas of the brain that interpret the passage of time begin telling the owner that this process may NEVER stop! I have seen this obsessive focus on a 'permanent' state of suffering in ALL recovering MDMA users. Interestingly, I have also noticed that my wife goes through a similar process of 'possibly permanent' anxiety when she is PMSing. Her brain tricks her into focusing on the

things in her life that have been bothering her, and she begins to make statements like, "I can't do this for another 40 years!" If you didn't know, serotonin is involved in the cortisol/prolactin release that is critical to a woman's cycle. I guarantee that the women in this group would say their recovery is more difficult during the week leading up to their period. One day this cycle of adrenaline and cortisol become SO great that the user has a freak-out.The LIMBIC system has been trying to gain control the whole time, and suddenly it has success!During this period of heightened anxiety a sudden rush of progress is made!Only when the brain is convinced that things have gotten worse and will NEVER get better....do more axons connect to the right pathways! Imagine several hundred or thousand axons suddenly BLOOM like flowers on a branch!Once the axons pop up, a healing plateau has been reached. This new storage capacity for

serotonin results in a drop in cortisol and a release of oxytocin/prolactin. The owner owner feels normal for a few days.Then the next cycle begins, because the new storage capacity is STILL not enough to contain the constant flow of serotonin being injected into the base of the brain.Now the piracetam is introduced.Before it took an extreme amount of cortisol to power this 'drilling' process. But not anymore.The piracetam has increased cellular permeability! I believe the first effect of the medication is on the serotonin receptors in the intestines. Because the receptors in the GUT are more permeable, there is more bile release and contraction of muscle tissue with LESS irritation of the villi.When the seretonin is injected into the base of the brain and begins to flow down the many branches of the network, the brain tissue is more accepting of this process. Less

cortisol is released, and MORE axons are able to sprout with a now reduced endocrine response. In fact, I feel that a much GREATER release of oxytocin/prolactin is allowed from this smaller amount of cortisol. I believe this is one of the reasons why the first few days on piracetam can be so emotionally profound for me. The cortisol present generates a sudden rush of good chemicals (oxytocin, dopamine)The 'drilling' sensation....the constant 'head pressure'....turns into a tickling sensation. Sometimes it is a strong tickle, sometimes a weak one. But I have noticed this on EACH cycle. The difference in sensation is like night and day. Simultaneously, I feel the 'lump' in my gut has smoothed out. Suddenly the intestines feel young and responsive again.Due to the increased permeability, many more axons are able to sprout, but there is still a 'building up' process. There is still a plateau stage. I

believe it is during the first major plateau that the piracetam becomes irritating. The brain is ready to relax and enjoy the new progress for a short period of time, but the continued presence of the drug is encouraging the next cycle to begin early. Also, choline is important in regards to cellular permeability. It is one of the salt ions present in the membrane of the cell. It is also used to synthesize the neurotransmitter acetylcholine. If piracetam is taking advantage of the effect of choline on these membranes, then it makes sense that more choline is needed than normal. Choline supplements have been used in the treatment of hepatitis, bi-polar disorder, Alzheimer's, and other neurological disorders.It may be nothing more than a shortage of choline that causes me to stop taking the Piracetam. Maybe it is just reaching a plateau. Maybe it is both.Perhaps my 'drilling' and 'tickling' description is nothing more than a crude

metaphor for a very complex process. Maybe I'm way off the mark here....but what I described is what I have been feeling. Food...villi....irritation...injection....antagonizing...cortisol....oxytocin....plateau....food....villi....on and on it goes. The cycle doesn't end....because your GUT is in control, not your brain. One day, your gut will stop this drilling process. I don't believe it can go on forever. Even for those that have been suffering 5-10 years, I bet the cortisol release has become much more tolerable with time. Faded into the background.There has to be a final plateau...I hope that ALL of us get there one day. No matter WHERE you fall on the spectrum, I believe there is still hope. Take fish oil, b-vitamins, choline, anti-inflammatory agents.Exercise, even if you don't think you can control your muscles at all.And yes, try the piracetam. But do the rest....I do. Who knows if I could report such

fast progress if I ONLY took the piracetam. I am fighting this as hard as I can. And I find a strange satisfaction in being able to help others along the way.Ben, let us know how the piracetam works for you.Good luck to all of you.

[Guest guest]

http://www.newyorker.com/reporting/2009/04/27/090427fa_fact_talbot?currentPage=a\

ll

http://www.smart-nutrition.net/South-piracetam.htm

Read more

http://www.newyorker.com/reporting/2009/04/27/090427fa_fact_talbot#ixzz1Hr6Jnjyp\

Seltzer considers himself a " transhumanist, " in the mold of the Oxford

philosopher Nick Bostrom and the futurist writer and inventor Ray Kurzweil.

Transhumanists are interested in robots, cryogenics, and living a really, really

long time; they consider biological limitations that the rest of us might

accept, or even appreciate, as creaky obstacles to be aggressively surmounted.

On the ImmInst forums— " ImmInst " stands for " Immortality Institute " —Seltzer and

other members discuss life-extension strategies and the potential benefits of

cognitive enhancers. Some of the forum members limit themselves to vitamin and

mineral supplements. Others use Adderall or modafinil or, like Seltzer, a drug

called piracetam, which was first marketed by a Belgian pharmaceutical company

in 1972 and, in recent years, has become available in the U.S. from retailers

that sell supplements. Although not approved for any use by the F.D.A.,

piracetam has been used experimentally on stroke patients—to little effect—and

on patients with a rare neurological condition called progressive myoclonus

epilepsy, for whom it proved helpful in alleviating muscle spasms. Data on

piracetam's benefits for healthy people are virtually nonexistent, but many

users believe that the drug increases blood flow to the brain.

[Guest guest]

The second link, which supports the use of Piracetam, contains LOADS more information on the studies behind it.The first link hardly discusses science at all.First, the F.D.A. is given a title and respect it never earned. It is argued by many that the FDA has made many mistakes, some of them vast. They are hardly capable of establishing the effectiveness of many drugs, including this one. They have also approved many other they should not have.The data being 'nonexistant' for healthy people simply indicates that either they are not doing enough research OR the drug is only effective for those with a deficit. Wouldn't that describe this group?Not to be rude, but what was the point of this email?Are you

discouraging the use of this drug? Supporting it? Just throwing information out there?Not only can I personally vouch for its effectiveness, but hopefully our friend Ben will be doing the same in the near future. Others in this group have also said that it worked well for them.If it didn't work for you, please say so. That would be more helpful than what I see in this email.You have my sympathies if the piracetam has had no effect for you, but I cannot sit by silently.To: SSRIsex Sent: Mon, March 28, 2011 4:14:20

AMSubject: Re: Former MDMA user offers medication advice!

http://www.newyorker.com/reporting/2009/04/27/090427fa_fact_talbot?currentPage=all

http://www.smart-nutrition.net/South-piracetam.htm

Read more http://www.newyorker.com/reporting/2009/04/27/090427fa_fact_talbot#ixzz1Hr6JnjypSeltzer considers himself a "transhumanist," in the mold of the Oxford philosopher Nick Bostrom and the futurist writer and inventor Ray Kurzweil. Transhumanists are interested in robots, cryogenics, and living a really, really long time; they consider biological limitations that the rest of us might accept, or even appreciate, as creaky obstacles to be aggressively surmounted. On the ImmInst forums—"ImmInst" stands for "Immortality Institute"—Seltzer and other members discuss life-extension strategies and the potential benefits of cognitive enhancers. Some of the forum members limit themselves to vitamin and mineral supplements. Others use Adderall or modafinil or, like Seltzer, a drug called piracetam, which was first marketed by a Belgian

pharmaceutical company in 1972 and, in recent years, has become available in the U.S. from retailers that sell supplements. Although not approved for any use by the F.D.A., piracetam has been used experimentally on stroke patients—to little effect—and on patients with a rare neurological condition called progressive myoclonus epilepsy, for whom it proved helpful in alleviating muscle spasms. Data on piracetam's benefits for healthy people are virtually nonexistent, but many users believe that the drug increases blood flow to the brain.

[Guest guest]

Wow, very glad to hear it!These are strong statements - 'all my emotions' and 'totally lifted'...The contrast is like night and day, isn't it?This is why I said that the piracetam feels like rolling on MDMA to me. The emotions are profound.You can taste the serotonin in your saliva, can't you?Don't expect all libido to come rushing back at once, though. I do recommend abusing what you have, though. Trust me Ben, if you start stimulating your libido it will respond.I have found that forcing myself to have sex or masturbate several days in a row resulted in drastic improvements in both libido and quality of orgasm.Word of caution: This improvement is temporary. I don't want you to lose hope in any way, but I must warn you that you will start

getting used to feeling good again. Eventually the 'contrast' between how you feel and how you used to feel fades. You will simply feel normal.That is our goal right?But, since I have chosen to cycle on and off this medication, I can tell you that the piracetam is not an instant fix, even though it feels like one.If you stop the medication, you will realize, to your dismay, that your brain defect is still present.Remember, in schizophrenic patients, the piracetam improves the symptoms - but does not alter their 'diseased state'.Harsh words, but true. Maybe a little too harsh...I do believe the piracetam has helped speed up my recovery process, though! I can still feel 'head pressure' while on it, but it feels more like tingling...Even if it is slowing down my recovery, I consider it worth it because this stuff has given

hope to a desperate man - ME.I am currently about 2 weeks into my OFF cycle. I have been pleasantly surprised that my anxiety has not been so extreme this time.In fact, I had to eat WAY too much to really notice the anxiety this time. But once I did, it kept me up all night....mind racing for hours.I have felt a little flat for the last few days, including my libido. I even started to think this will never get better again!Its amazing how effective this disorder is at convincing the brain that its current state is permanent!However, despite feeling 'flat'.... I still had morning wood two days in a row!I'll tell you more....a few days ago, while out of town for my great-grandma's funeral....I was sleeping in the hotel room with my family.I had a fucking nocturnal emission. :-0I must say, even before this MDMA thing fucked me up, I NEVER had wet dreams.....maybe three times in my whole damn life!Now

I had one....and days later I feel like I'm about to have more...despite the fact that during the day my libido seems faded because I'm off the piracetam...In my research I have learned that oxytocin/prolactin levels are at their lowest early in the morning....just before waking.That means the brain has more dopamine....because dopamine and prolactin have an inverse relationship.So to Ben and the rest of us, I would be very hopeful to see night or morning erections.I am excited about starting my next cycle of piracetam....this time with choline. And maybe the insotol too!Keep us updated....I will do the same.To: SSRIsex Sent: Tue, March 29, 2011 10:33:23 AMSubject: Re: Finally cured after 2 years of hell

I am feeling all my emotions come back lately and the depression and anxiety has totally lifted. It feels great. I feel more libido too. Nothing off the charts but certainly feeling it!

> > > > >

> > > > > Background about me: I'm a 27 year old male. I was put onPaxil for

> social

> > >anxiety disorder. After a few months, I found it really hard to orgasm. I was

> > >having marathon sex sessions with my wife. I went off the Paxil in March of

> >2009

> > >(after a total of 8 months on it) and since then I've noticed that it takes

> me

> > >forever to get aroused. I've also been hit with extreme premature

> ejaculation,

> > >loss of libido and interest in sex.

> > > > >

> > > > > After trying a few products mentioned by people here that didn't work, I

> > >decided to look at the matter scientifically. PSSD is most likely caused by

> > >persistent desensitization of 5-HT1A receptors. After doing some research on

> > >substances that reverse desensitization of these receptors I stumbled across

> > >inositol, a naturally occuring sugar in our bodies.

> > > > >

> > > > > I've been on 18 grams of inositol once daily at bedtime for the past 7

> > >weeks and few days (Jan 24/2011 to March 16/2011) and I am happy to say that

> >my

> > >interest in sex has returned, my erections are back to normal, and my

> >premature

> > >ejaculation has returned to how it was before I went on Paxil. Never will I

> > >touch an SSRI again.

> > > > >

> > > > > I hope this will help anyone who is still trying to get rid of this

> > >horrible peoplem.

> > > > >

> > > > > Greg

> > > > >

> > > >

> > >

> >

>

[Guest guest]

Hey Sam

Hey Man did you get my private message.

Peace, Adam

To: SSRIsex Sent: Tue, March 29, 2011 2:11:37 PMSubject: Re: Former MDMA user offers medication advice!

Wow, very glad to hear it!These are strong statements - 'all my emotions' and 'totally lifted'...The contrast is like night and day, isn't it?This is why I said that the piracetam feels like rolling on MDMA to me. The emotions are profound.You can taste the serotonin in your saliva, can't you?Don't expect all libido to come rushing back at once, though. I do recommend abusing what you have, though. Trust me Ben, if you start stimulating your libido it will respond.I have found that forcing myself to have sex or masturbate several days in a row resulted in drastic improvements in both libido and quality of orgasm.Word of caution: This improvement is temporary. I don't want you to lose hope in any way, but I must warn you that you will start getting used to feeling good again. Eventually the 'contrast' between how you feel and how you used to feel fades. You will simply feel

normal.That is our goal right?But, since I have chosen to cycle on and off this medication, I can tell you that the piracetam is not an instant fix, even though it feels like one.If you stop the medication, you will realize, to your dismay, that your brain defect is still present.Remember, in schizophrenic patients, the piracetam improves the symptoms - but does not alter their 'diseased state'.Harsh words, but true. Maybe a little too harsh...I do believe the piracetam has helped speed up my recovery process, though! I can still feel 'head pressure' while on it, but it feels more like tingling...Even if it is slowing down my recovery, I consider it worth it because this stuff has given hope to a desperate man - ME.I am currently about 2 weeks into my OFF cycle. I have been pleasantly surprised that my anxiety

has not been so extreme this time.In fact, I had to eat WAY too much to really notice the anxiety this time. But once I did, it kept me up all night....mind racing for hours.I have felt a little flat for the last few days, including my libido. I even started to think this will never get better again!Its amazing how effective this disorder is at convincing the brain that its current state is permanent!However, despite feeling 'flat'.... I still had morning wood two days in a row!I'll tell you more....a few days ago, while out of town for my great-grandma's funeral....I was sleeping in the hotel room with my family.I had a fucking nocturnal emission. :-0I must say, even before this MDMA thing fucked me up, I NEVER had wet dreams.....maybe three times in my whole damn life!Now I had one....and days later I feel like I'm about to have more...despite the fact that during the day my libido seems faded because I'm

off the piracetam...In my research I have learned that oxytocin/prolactin levels are at their lowest early in the morning....just before waking.That means the brain has more dopamine....because dopamine and prolactin have an inverse relationship.So to Ben and the rest of us, I would be very hopeful to see night or morning erections.I am excited about starting my next cycle of piracetam....this time with choline. And maybe the insotol too!Keep us updated....I will do the same.

To: SSRIsex Sent: Tue, March 29, 2011 10:33:23 AMSubject: Re: Finally cured after 2 years of hell

I am feeling all my emotions come back lately and the depression and anxiety has totally lifted. It feels great. I feel more libido too. Nothing off the charts but certainly feeling it! > > > > >> > > > > Background about me: I'm a 27 year old male. I was put onPaxil for> social> > >anxiety disorder. After a few months, I found it really hard to orgasm. I was> > >having marathon sex sessions with my wife. I went off the Paxil in March of> >2009> > >(after a total of 8 months on it) and since then I've noticed that it takes> me> > >forever to get aroused. I've also been hit with extreme

premature> ejaculation,> > >loss of libido and interest in sex.> > > > >> > > > > After trying a few products mentioned by people here that didn't work, I> > >decided to look at the matter scientifically. PSSD is most likely caused by> > >persistent desensitization of 5-HT1A receptors. After doing some research on> > >substances that reverse desensitization of these receptors I stumbled across> > >inositol, a naturally occuring sugar in our bodies.> > > > >> > > > > I've been on 18 grams of inositol once daily at bedtime for the past 7> > >weeks and few days (Jan 24/2011 to March 16/2011) and I am happy to say that> >my> > >interest in sex has returned, my erections are back to normal, and my> >premature> > >ejaculation has returned to how it was

before I went on Paxil. Never will I> > >touch an SSRI again.> > > > >> > > > > I hope this will help anyone who is still trying to get rid of this> > >horrible peoplem.> > > > >> > > > > Greg> > > > >> > > >> > >> >>

[Guest guest]

Want to report increased libido today and PRECUM for the first time in GOD knows

how long, maybe over a year.

That really struck me. Plus a much higher ejaculate volume.

> >

> > From: Sam Sam <onenightonlydfw@>

> > Subject: Re: Former MDMA user offers medication advice!

> > To: SSRIsex

> > Received: Friday, 18 March, 2011, 3:13 AM

> >

> >

> >

> >

> >

> >

> >

> > Â

> >

> >

> >

> >

> >

> >

> >

> >

> >

> > I bought the cheapest one I could find on Google. It's called

> > " Nooracetam " .

> > It was $20 with shipping for 90 pills. One pill lasts me at least 3 days!

> > I HIGHLY recommend taking small doses with 2 fish oil pills. The fish oil

makes

> >a big difference.

> >

> > I have heard many people say that they get headaches, especially after

several

> >days...because their choline supply is used up. I feel fine for two to three

> >weeks because I am taking tiny doses. I will try it with choline supplements

on

> >my next round.

> >

> > Yes, in my first two months I felt numbness in many parts of my body. The

lower

> >on the body, the worse it seemed. The bottoms of my feet were numb, and yes

my

> >thighs too. BUT the most noticeable was the penis, testicles, and anus which,

in

> >contrast to their

> > normal status, were obviously numb. I was surprised that my penis seemed

> >completely weightless. The ligaments that suspend the organ from the body are

> >used to feeling the gentle tugging downward caused by gravity. But suddenly

the

> >organ had zero mass to it. Make sense?

> >

> > Yes, the piracetam can cause its own type of anxiety, but I find this is

> >completely avoided by taking very small doses. I literally open the capsule,

> >pour about 15% of the powder out, then lick it off a plate! It tastes bitter,

> >but dissolves much quicker on the tongue than other medications. I take this

> >dose normally twice a day. By day two or three, you should notice a big

change.

> >When I was at my worst, I noticed the change within hours of the first dose.

> >

> > IF you chose to take a whole capsule, don't worry too much about the

anxiety,

> >because it is not nearly as bad as what you have already been

> > through! It feels different. Mainly, I feel irritated and argumentative for

a

> >couple of hours - but not too much physical tension. This unpleasant part

will

> >go away after a few hours. You will feel the increased blood-flow right

behind

> >your forehead! It tickles for several hours.....much better than the constant

> >'head pressure' I had before. You can really feel the brain juices flowing!

> >

> > Now the BIG question: Does the piracetam halt the normal healing process?

> > My answer: maybe, but I doubt it.

> >

> > Bigger question: does it 'undo' the healing process?

> > My answer: I am nearly certain that it doesn't!

> >

> > I have cycled on and off this medication 3 times already. I am about to go

for

> >number 4.

> > Each time I discontinue usage, my feeling of numbness and anxiety return,

but

> >not NEARLY as badly as before. In other words, after 3-4 weeks of taking the

> >piracetam I do NOT slide all the way back to where I was before the cycle. It

> >takes several

> > days to a week to notice feelings of sadness. It really sneaks up on me,

> >though. I have to remind myself that it is supposed to happen.

> >

> > In schizophrenia, piracetam DOES alleviate symptoms, but it does not " alter

> >their diseased state " .

> >

> > I believe we are suffering from a type of schizophrenia. That is why so many

of

> >us are frantic or constantly obsessed with our horrid symptoms. Schizophrenia

is

> >associated with an overabundance of dopamine. I think a lack of serotonin

> >receptors is causing our dopamine pathways to remain disconnected. The body's

> >response is to push on your fight/flight reflex, which releases adrenaline

and

> >cortisol all day. After days or weeks of that crap, you freak out, causing

the

> >built-up dopamine to 'spill over' into the nearby pathways. You have just

made

> >some new connections every time you freak out! That is another great reason

to

> >exercise people! Maybe the piracetam is simply

> > allowing the dopamine to get where it wants to go...

> >

> > I have also noticed that with each cycle - my orgasms continue to get

> stronger!

> > This is a sign that the brain adaptations are still happening!

> > Either the healing process starts up again between cycles OR it never stops

> >during the cycles!

> > This is the bottom line to me. I haven't noticed a halting in my progress.

It

> >is a continuous forward march!

> >

> > Also, at the end of my first cycle, the 'over-stimulation' I felt from the

> >piracetam was more severe than the last two cycles. I was taking 2 whole

pills

> >per day. One day early on I was so excited by the changes I took 5 pills in

one

> >day. I felt so stimulated by it I stayed up reading all night! I even did my

> >resume at 6 AM! But the next

> > day really sucked. I was freezing cold, tremors all over, and had a

terrible

> >headache. I learned my lesson and reduced my dose. Then I was fine.

> >

> > By the end of the month, I was starting to have weird 'eye jerks'. The

muscles

> >under my right eyelid would twitch ever so slightly, but lightening fast.

> >Sometimes 10-15 twitches in a row, up to 20 times a day! This is called a

> >myoclonic seisure. It was not painful or scary, but it was irritating enough

to

> >tell me to stop taking it. After a week off the drug, my eye jerks went away

for

> >good. They have not yet returned. Please keep in mind that my first cycle was

my

> >most intense, because of the higher dose and the proximity to my MDMA abuse.

> >

> > The break after my first cycle lasted a month. Within a week I started to

cry

> >and feel empty again, but the head-pressure and tingling in my brain came

back

> >too. By 10 days, I was having my first anxiety attack, and I realized that

the

> >healing process was STILL

> > going on! The next day, I felt great! I didn't need the piracetam to 'break

> >through' these attacks. It was all too similar to the way I 'broke through'

them

> >before the first cycle.

> >

> > Then my second cycle was much smaller doses. I had little or NO anxiety

while

> >on it. After another month on it, I felt very mild headaches and slight

> >stimulation. It feels like the drug starts to build up in my system after

taking

> >it for a while. The stimulation is wonderful in the first three weeks! Then,

it

> >starts to increase ever so slightly towards unpleasantness. When I stopped

> >taking it in week four, I noticed that the stimulation tapered down over

several

> >days. During this 'tapering off' period, I actually felt BETTER. My brain

began

> >thinking faster and processing thoughts and feelings like I was in week one

> >again! It seems to me there is a sweet spot with this medication.

> >

> > My third cycle was unusual, because I didn't wait a whole month in between.

> >This

> > time it was my wife's anxiety that caused me to start up again. She was

having

> >a hard time dealing with me going back and forth, and frankly she wanted sex.

> >:-) So I started my dosing again after only a 10 day break. Once again, all

the

> >positive changes occurred - my penis felt great....my orgasms were even

BETTER

> >than the second cycle. BUT I have found that only 2 weeks back on the

piracetam

> >is necessary to feel over-stimulated again.

> >

> > I am now 4 days off the medication again. I am just now starting to feel

down,

> >again. But it feels like this time will be easier than the last. After all, I

am

> >sitting here typing like mad, so I can't be that bad yet! I won't be so sure

> >until another week has passed. I will keep all of you posted. I am

considering

> >doing two week long cycles instead of 30 days.

> > If the next cycle on the piracetam sees yet ANOTHER improvement in

> > sexual function, I will consider it absolute PROOF that I am NOT reversing

the

> >progress I have made!

> >

> > NOTE: the strangest thing I have noticed during my on/off cycles has to do

with

> >my shit.

> > When I am off the drug, my poop comes out a much lighter color - an

indication

> >that bile production has gone down. It also is less 'formed' - meaning that

> >muscle contractions in the intestines are lessened.

> >

> > When I go back ON the drug, my poop becomes immediately darker and more

formed.

> >Obviously so.

> > I am not crazy, just a little obsessive. And comfortable with my anus!

> > I have looked at every bowel movement since this began, and I can safely say

> >this correlation holds up EVERY time.

> > Piracetam helps me poop better, too!

> >

> > I hope I have managed to bring a smile and some hope to each of you today.

> > I will keep the group updated. I will let you know when I hit my anxiety and

> >sadness again.

> >

> > Then I will come back and tell you when I start

> > my next cycle.

> > If the improvements continue for me - I will issue a strong edict that

everyone

> >jump on the piracetam train!

> >

> > Good luck. Good night.

> >

>

[Guest guest]

how is the Piracetam going?

> > >

> > > From: Sam Sam <onenightonlydfw@>

> > > Subject: Re: Former MDMA user offers medication advice!

> > > To: SSRIsex

> > > Received: Friday, 18 March, 2011, 3:13 AM

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > > Â

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > >

> > > I bought the cheapest one I could find on Google. It's called

> > > " Nooracetam " .

> > > It was $20 with shipping for 90 pills. One pill lasts me at least 3 days!

> > > I HIGHLY recommend taking small doses with 2 fish oil pills. The fish oil

makes

> > >a big difference.

> > >

> > > I have heard many people say that they get headaches, especially after

several

> > >days...because their choline supply is used up. I feel fine for two to

three

> > >weeks because I am taking tiny doses. I will try it with choline

supplements on

> > >my next round.

> > >

> > > Yes, in my first two months I felt numbness in many parts of my body. The

lower

> > >on the body, the worse it seemed. The bottoms of my feet were numb, and yes

my

> > >thighs too. BUT the most noticeable was the penis, testicles, and anus

which, in

> > >contrast to their

> > > normal status, were obviously numb. I was surprised that my penis seemed

> > >completely weightless. The ligaments that suspend the organ from the body

are

> > >used to feeling the gentle tugging downward caused by gravity. But suddenly

the

> > >organ had zero mass to it. Make sense?

> > >

> > > Yes, the piracetam can cause its own type of anxiety, but I find this is

> > >completely avoided by taking very small doses. I literally open the

capsule,

> > >pour about 15% of the powder out, then lick it off a plate! It tastes

bitter,

> > >but dissolves much quicker on the tongue than other medications. I take

this

> > >dose normally twice a day. By day two or three, you should notice a big

change.

> > >When I was at my worst, I noticed the change within hours of the first

dose.

> > >

> > > IF you chose to take a whole capsule, don't worry too much about the

anxiety,

> > >because it is not nearly as bad as what you have already been

> > > through! It feels different. Mainly, I feel irritated and argumentative

for a

> > >couple of hours - but not too much physical tension. This unpleasant part

will

> > >go away after a few hours. You will feel the increased blood-flow right

behind

> > >your forehead! It tickles for several hours.....much better than the

constant

> > >'head pressure' I had before. You can really feel the brain juices flowing!

> > >

> > > Now the BIG question: Does the piracetam halt the normal healing process?

> > > My answer: maybe, but I doubt it.

> > >

> > > Bigger question: does it 'undo' the healing process?

> > > My answer: I am nearly certain that it doesn't!

> > >

> > > I have cycled on and off this medication 3 times already. I am about to go

for

> > >number 4.

> > > Each time I discontinue usage, my feeling of numbness and anxiety return,

but

> > >not NEARLY as badly as before. In other words, after 3-4 weeks of taking

the

> > >piracetam I do NOT slide all the way back to where I was before the cycle.

It

> > >takes several

> > > days to a week to notice feelings of sadness. It really sneaks up on me,

> > >though. I have to remind myself that it is supposed to happen.

> > >

> > > In schizophrenia, piracetam DOES alleviate symptoms, but it does not

" alter

> > >their diseased state " .

> > >

> > > I believe we are suffering from a type of schizophrenia. That is why so

many of

> > >us are frantic or constantly obsessed with our horrid symptoms.

Schizophrenia is

> > >associated with an overabundance of dopamine. I think a lack of serotonin

> > >receptors is causing our dopamine pathways to remain disconnected. The

body's

> > >response is to push on your fight/flight reflex, which releases adrenaline

and

> > >cortisol all day. After days or weeks of that crap, you freak out, causing

the

> > >built-up dopamine to 'spill over' into the nearby pathways. You have just

made

> > >some new connections every time you freak out! That is another great reason

to

> > >exercise people! Maybe the piracetam is simply

> > > allowing the dopamine to get where it wants to go...

> > >

> > > I have also noticed that with each cycle - my orgasms continue to get

> > stronger!

> > > This is a sign that the brain adaptations are still happening!

> > > Either the healing process starts up again between cycles OR it never

stops

> > >during the cycles!

> > > This is the bottom line to me. I haven't noticed a halting in my progress.

It

> > >is a continuous forward march!

> > >

> > > Also, at the end of my first cycle, the 'over-stimulation' I felt from the

> > >piracetam was more severe than the last two cycles. I was taking 2 whole

pills

> > >per day. One day early on I was so excited by the changes I took 5 pills in

one

> > >day. I felt so stimulated by it I stayed up reading all night! I even did

my

> > >resume at 6 AM! But the next

> > > day really sucked. I was freezing cold, tremors all over, and had a

terrible

> > >headache. I learned my lesson and reduced my dose. Then I was fine.

> > >

> > > By the end of the month, I was starting to have weird 'eye jerks'. The

muscles

> > >under my right eyelid would twitch ever so slightly, but lightening fast.

> > >Sometimes 10-15 twitches in a row, up to 20 times a day! This is called a

> > >myoclonic seisure. It was not painful or scary, but it was irritating

enough to

> > >tell me to stop taking it. After a week off the drug, my eye jerks went

away for

> > >good. They have not yet returned. Please keep in mind that my first cycle

was my

> > >most intense, because of the higher dose and the proximity to my MDMA

abuse.

> > >

> > > The break after my first cycle lasted a month. Within a week I started to

cry

> > >and feel empty again, but the head-pressure and tingling in my brain came

back

> > >too. By 10 days, I was having my first anxiety attack, and I realized that

the

> > >healing process was STILL

> > > going on! The next day, I felt great! I didn't need the piracetam to

'break

> > >through' these attacks. It was all too similar to the way I 'broke through'

them

> > >before the first cycle.

> > >

> > > Then my second cycle was much smaller doses. I had little or NO anxiety

while

> > >on it. After another month on it, I felt very mild headaches and slight

> > >stimulation. It feels like the drug starts to build up in my system after

taking

> > >it for a while. The stimulation is wonderful in the first three weeks!

Then, it

> > >starts to increase ever so slightly towards unpleasantness. When I stopped

> > >taking it in week four, I noticed that the stimulation tapered down over

several

> > >days. During this 'tapering off' period, I actually felt BETTER. My brain

began

> > >thinking faster and processing thoughts and feelings like I was in week one

> > >again! It seems to me there is a sweet spot with this medication.

> > >

> > > My third cycle was unusual, because I didn't wait a whole month in

between.

> > >This

> > > time it was my wife's anxiety that caused me to start up again. She was

having

> > >a hard time dealing with me going back and forth, and frankly she wanted

sex.

> > >:-) So I started my dosing again after only a 10 day break. Once again, all

the

> > >positive changes occurred - my penis felt great....my orgasms were even

BETTER

> > >than the second cycle. BUT I have found that only 2 weeks back on the

piracetam

> > >is necessary to feel over-stimulated again.

> > >

> > > I am now 4 days off the medication again. I am just now starting to feel

down,

> > >again. But it feels like this time will be easier than the last. After all,

I am

> > >sitting here typing like mad, so I can't be that bad yet! I won't be so

sure

> > >until another week has passed. I will keep all of you posted. I am

considering

> > >doing two week long cycles instead of 30 days.

> > > If the next cycle on the piracetam sees yet ANOTHER improvement in

> > > sexual function, I will consider it absolute PROOF that I am NOT

reversing the

> > >progress I have made!

> > >

> > > NOTE: the strangest thing I have noticed during my on/off cycles has to do

with

> > >my shit.

> > > When I am off the drug, my poop comes out a much lighter color - an

indication

> > >that bile production has gone down. It also is less 'formed' - meaning that

> > >muscle contractions in the intestines are lessened.

> > >

> > > When I go back ON the drug, my poop becomes immediately darker and more

formed.

> > >Obviously so.

> > > I am not crazy, just a little obsessive. And comfortable with my anus!

> > > I have looked at every bowel movement since this began, and I can safely

say

> > >this correlation holds up EVERY time.

> > > Piracetam helps me poop better, too!

> > >

> > > I hope I have managed to bring a smile and some hope to each of you today.

> > > I will keep the group updated. I will let you know when I hit my anxiety

and

> > >sadness again.

> > >

> > > Then I will come back and tell you when I start

> > > my next cycle.

> > > If the improvements continue for me - I will issue a strong edict that

everyone

> > >jump on the piracetam train!

> > >

> > > Good luck. Good night.

> > >

> >

>

[Guest guest]

What's a good dose of piracetam to start on?