Guest guest Posted February 24, 2011 Report Share Posted February 24, 2011 So today I drank some coffee before work. I do not usually drink coffee, but when i did (on lexapro, and before PSSD, but still having erection problems) caffeine always made me horny. During PSSD it helped a bit, but as things finally plateued and got to how bad they are around month 5 after the cold turkey, coffee stopped doing anything at all. Just recently though its been working again, and after seeing my morning erections and orgasms return i experienced something today profound. I was at work when It hit me like a ton of bricks. I felt ridiculously horny. Like almost like a maniac horny. The interesting thing was that it only triggered a small physical (as in erectile) reaction in my penis. The sensitivity was overwhelming though. I still felt that disconnect from the penis, like the brain/penis function, but it did move. The most important thing here is that the fantasizing made me so horny i could barely stand it. Where the heck did this come from!?? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 25, 2011 Report Share Posted February 25, 2011 so now every one can read it. the feelings realy can come back happiness has come our ways > > So today I drank some coffee before work. I do not usually drink coffee, but when i did (on lexapro, and before PSSD, but still having erection problems) caffeine always made me horny. > > During PSSD it helped a bit, but as things finally plateued and got to how bad they are around month 5 after the cold turkey, coffee stopped doing anything at all. > > Just recently though its been working again, and after seeing my morning erections and orgasms return i experienced something today profound. > > I was at work when It hit me like a ton of bricks. I felt ridiculously horny. Like almost like a maniac horny. The interesting thing was that it only triggered a small physical (as in erectile) reaction in my penis. The sensitivity was overwhelming though. I still felt that disconnect from the penis, like the brain/penis function, but it did move. The most important thing here is that the fantasizing made me so horny i could barely stand it. > > Where the heck did this come from!?? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 27, 2011 Report Share Posted February 27, 2011 Its mostly the dostinex/cabergoline's delayed effect. You said you were taking dostinex right?Subject: Holy wowTo: SSRIsex Date: Friday, February 25, 2011, 2:29 AM So today I drank some coffee before work. I do not usually drink coffee, but when i did (on lexapro, and before PSSD, but still having erection problems) caffeine always made me horny. During PSSD it helped a bit, but as things finally plateued and got to how bad they are around month 5 after the cold turkey, coffee stopped doing anything at all. Just recently though its been working again, and after seeing my morning erections and orgasms return i experienced something today profound. I was at work when It hit me like a ton of bricks. I felt ridiculously horny. Like almost like a maniac horny. The interesting thing was that it only triggered a small physical (as in erectile) reaction in my penis. The sensitivity was overwhelming though. I still felt that disconnect from the penis, like the brain/penis function, but it did move. The most important thing here is that the fantasizing made me so horny i could barely stand it. Where the heck did this come from!?? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 27, 2011 Report Share Posted February 27, 2011 Hmm i dont know about that. Its totally coincided with me starting to drink coffee again. Plus I ran out of dostinex Feb 14th and the lingering improvement with erections faded away within like a week. And the feeling of genital attachment faded away within a week as well. Orgasms are great right now and have been for a while. I get morning erections now too. My main problem is getting an erection and keeping it and the numbness associated with that. > > > Subject: Holy wow > To: SSRIsex > Date: Friday, February 25, 2011, 2:29 AM > > > > > > > > Â > > > > > > > > > > So today I drank some coffee before work. I do not usually drink coffee, but when i did (on lexapro, and before PSSD, but still having erection problems) caffeine always made me horny. > > > > During PSSD it helped a bit, but as things finally plateued and got to how bad they are around month 5 after the cold turkey, coffee stopped doing anything at all. > > > > Just recently though its been working again, and after seeing my morning erections and orgasms return i experienced something today profound. > > > > I was at work when It hit me like a ton of bricks. I felt ridiculously horny. Like almost like a maniac horny. The interesting thing was that it only triggered a small physical (as in erectile) reaction in my penis. The sensitivity was overwhelming though. I still felt that disconnect from the penis, like the brain/penis function, but it did move. The most important thing here is that the fantasizing made me so horny i could barely stand it. > > > > Where the heck did this come from!?? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted February 27, 2011 Report Share Posted February 27, 2011 Your recovery in the beginning will be on and off and will continue more frequent. Untill you will have full recovery. Hope that happens soon. Adil To: SSRIsex Sent: Sun, February 27, 2011 11:28:35 PMSubject: Re: Holy wow Hmm i dont know about that. Its totally coincided with me starting to drink coffee again. Plus I ran out of dostinex Feb 14th and the lingering improvement with erections faded away within like a week. And the feeling of genital attachment faded away within a week as well.Orgasms are great right now and have been for a while. I get morning erections now too.My main problem is getting an erection and keeping it and the numbness associated with that.> > > Subject: Holy wow> To: SSRIsex > Date: Friday, February 25, 2011, 2:29 AM> > > > > > > > Â > > > > > > > > > > So today I drank some coffee before work. I do not usually drink coffee, but when i did (on lexapro, and before PSSD, but still having erection problems) caffeine always made me horny.> > > > During PSSD it helped a bit, but as things finally plateued and got to how bad they are around month 5 after the cold turkey, coffee stopped doing anything at all.> > > > Just recently though its been working again, and after seeing my morning erections and orgasms return i experienced something today profound.> > > > I was at work when It hit me like a ton of bricks. I felt ridiculously horny. Like almost like a maniac horny. The interesting thing was that it only triggered a small physical (as in erectile) reaction in my penis. The sensitivity was overwhelming though. I still felt that disconnect from the penis, like the brain/penis function, but it did move. The most important thing here is that the fantasizing made me so horny i could barely stand it.> > > > Where the heck did this come from!??> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 6, 2011 Report Share Posted March 6, 2011 I'd like to report that things keep getting better. I wake up every morning with good erections. Numbness isn't constant, it fluctuates now. Sensitivity is getting better Orgasms are great Erections are getting much better. And the best part. I feel horny sometimes and have a response in my penis. I feel like I am almost ready to go after some girls Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 Are you still taking something? > > I'd like to report that things keep getting better. > > I wake up every morning with good erections. > Numbness isn't constant, it fluctuates now. > Sensitivity is getting better > Orgasms are great > Erections are getting much better. > > And the best part. I feel horny sometimes and have a response in my penis. I feel like I am almost ready to go after some girls > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 Nope! Havent taken anything since Feb 14th. I drink 2 cups of coffee a day, and thats the only thing remotely differnt. > > > > I'd like to report that things keep getting better. > > > > I wake up every morning with good erections. > > Numbness isn't constant, it fluctuates now. > > Sensitivity is getting better > > Orgasms are great > > Erections are getting much better. > > > > And the best part. I feel horny sometimes and have a response in my penis. I feel like I am almost ready to go after some girls > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 Okay great!! So, how long exactly did you use Dostinex for? And what was the dosage?Subject: Re: Holy wowTo: SSRIsex Date: Monday, March 7, 2011, 6:48 PM Nope! Havent taken anything since Feb 14th. I drink 2 cups of coffee a day, and thats the only thing remotely differnt. > > > > I'd like to report that things keep getting better. > > > > I wake up every morning with good erections. > > Numbness isn't constant, it fluctuates now. > > Sensitivity is getting better > > Orgasms are great > > Erections are getting much better. > > > > And the best part. I feel horny sometimes and have a response in my penis. I feel like I am almost ready to go after some girls > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 I took 2 mg. staggered by 2 days in between doses. I took that like maybe 4 times. Thats it. I would rather not take any drugs, and the improvements seem to be speeding up. They come and go, but on a good day I don't have to worry about whether or not i will get it up. And for the first time in forever I have gotten erections while in the shower without porn and just fantasizing! So things are def coming back. The coffee for me helps a lot i think. -Ben > > > > > > > > I'd like to report that things keep getting better. > > > > > > > > I wake up every morning with good erections. > > > > Numbness isn't constant, it fluctuates now. > > > > Sensitivity is getting better > > > > Orgasms are great > > > > Erections are getting much better. > > > > > > > > And the best part. I feel horny sometimes and have a response in my penis. I feel like I am almost ready to go after some girls > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 7, 2011 Report Share Posted March 7, 2011 Good luck ben! > > So today I drank some coffee before work. I do not usually drink coffee, but when i did (on lexapro, and before PSSD, but still having erection problems) caffeine always made me horny. > > During PSSD it helped a bit, but as things finally plateued and got to how bad they are around month 5 after the cold turkey, coffee stopped doing anything at all. > > Just recently though its been working again, and after seeing my morning erections and orgasms return i experienced something today profound. > > I was at work when It hit me like a ton of bricks. I felt ridiculously horny. Like almost like a maniac horny. The interesting thing was that it only triggered a small physical (as in erectile) reaction in my penis. The sensitivity was overwhelming though. I still felt that disconnect from the penis, like the brain/penis function, but it did move. The most important thing here is that the fantasizing made me so horny i could barely stand it. > > Where the heck did this come from!?? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 5, 2011 Report Share Posted April 5, 2011 Just wanted to drop a line to you guys to give you some hope. I am about 13 months off Lexapro and 2 months off Zyprexa and the improvements keep coming. I am now starting to feel sexual attraction and romantic feelings again. Very on and off right now, but I feel that flutter and response in the genitals. My erections are much better, and the numbness is improving too! I have good orgasms 100% of the time and GREAT ones like 30%. Visual stimulation is finally starting to come back. I can honestly say that being positive, eating right, fish oil, vitamins and the piracetam has helped the most. The anhedonia is lifting almost completely and the depression is getting much better. I can see things just getting better and better. Soon I will be ready to go after some girls! yay! -Ben Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 6, 2011 Report Share Posted April 6, 2011 First, Ben - I am very happy to hear the piracetam has made a profound difference for you.I found myself wandering onto paxilprogress last week and discovered many of your posts there. I must say I feel some real sympathy for you, and I am very pleased to hear your story is turning around.I truly believe that your recent progress is a REAL sign of eventual recovery.BUT, I feel obligated to remind you of my experience...When I stop taking the piracetam I slowly drift back into anhedonia. And eventually maybe even panic attacks...In research involving schizophrenia (something we have a lot in common with) piracetam improves the patient's condition without actually curing the 'diseased state'. To me this means there is a structural defect in the brain that does not change, but is somehow 'bypassed' by this medication. The piracetam makes the cells more permeable, so if there are neurotransmitters trying to reach nearby receptors...they are more likely to cross the barrier. Make sense?Restore the membranes to their previous state, and the neurotransmitters stop crossing the barrier.I hate being the bearer of bad news, but neither of us are cured....YET.Now, for the good news.I am in the first week of my 4th cycle ON the piracetam.Being OFF was the reason I stopped emailing the group last week.However, I was surprised that during this OFF cycle, it took MUCH longer for me to disconnect from the world.And even after I did, my 'panic attacks' were much milder. It still managed to sneak up on me though...In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel the anhedonia....both sexually and emotionally. This time, it took 2 whole weeks!This is a true sign of progress to me. This is also a confirmation that the use of piracetam is not going to stop or harm the healing process.I was hoping to deliver such news to the group.I must also report that it took 4 days back ON the drug, to experience relief again. Before it happened much quicker, usually within the first 12-36 hours.I will say that during the first 2 days back ON, my anxiety ramped up big time. I also got very weird sensations in my lower intestines. I think it is at the ileum - the valve connecting the small and large intestine. It felt like I had a WORM crawling around inside me....seriously.To go even further....as this worm sensation was crawling around my intestines....I could feel it tickling in certain parts of my brain.I swear to God, people....i'm not crazy.As the intestines begin re-wiring themselves there are very specific increases in blood flow to certain brain regions.It is such a creepy feeling....and it is much more difficult to notice when i am OFF the piracetam. But it is still there.I encourage everyone on this email group to pay VERY close attention to the intestines when they are feeling anxiety. I have noticed several times that when I have a real panic attack....I feel flushing down below. It is never obvious, because this is smooth involuntary muscle....but I DO feel it happening. Especially after a major crying episode....I am more likely to feel a subtle flushing sensation.I guarantee that fasting for several days would bring relief to just about anyone here that is still experiencing anxiety and head pressure.I am also certain that the continual operation of the intestines is at the root of the healing process as well as the anhedonia.The intestines are home to the vast majority of serotonin and serotonin receptors. 95% of both.The process of digestion involves both the production of bile and the contraction of smooth muscle. Tryptophan is turned into bile AND serotonin....which is critical for the contraction of smooth muscle...both in the intestines and the genitals.The serotonin receptors in the brain are KNOWN to play a critical role in blood distribution. The more receptors in a section of brain tissue, the more blood vessels you will find there.Former users of MDMA, such as myself, have been shown to experience decreases in blood flow to many regions of the brain.Some will ALSO experience increases of blood flow to these areas....sometimes for many months after. This is known to be a sign of neurotoxicity AND of recovery.Amazingly, bloodflow is eventually restored to normal levels in all brain regions! Although it can take more than a year for many patients, and there is a belief that other cell types, such as GABA receptors are being modified during this process.The serotonergic system is one of the most complex structures in the brain and the nervous system.But remember, that the majority of your serotonin is NOT in the brain....its in the gut.I firmly believe that we have all damaged part of the vast connection between the intestines and the brain.I also believe that certain areas of the brain are more susceptible to this damage.Most likely it would be the areas that are affected positively when we are under the influence of SSRIs or MDMA.Unfortunately the emotional and sexual centers of the brain appear to lie within these more vulnerable areas.The frontal and prefrontal cortex are innervated by fiber like serotonin axons....much smaller and possibly more fragile than the rest of the network.I believe that these areas are connected to the lower part of the small intestines....and possibly the large intestines.When the front of the brain experiences serotonergic damage, the ileum down to the genitals are disconnected.The serotonin receptors in the smooth muscle is no longer attached to the network...BUT, the human body does not give up, either. Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause gliosis....or scar tissue to form. This allows for axons to re-sprout from the serotonin cell body.I believe that the villi in the intestines are sending constant signals of irritation....or tickling...up the spinal cord.This results in serotonin being injected into the base of the brain.The long branches of the serotonin network start pulsing....as if they were swelling with the neurotransmitter. The cell body itself is immune to the damage done by the drug....so this pressure is exerted along the whole cell body.When enough pressure builds up....or cortisol....new axons suddenly sprout from the cell body.The axons are more likely to sprout on the cell bodies closer to the back of the brain. After enough axons sprout in the REAR of the brain, the pressure being exerted on the network begins to target areas closer to the face. This is a back to front motion. Brain scans (SPECT) show that former MDMA users display a gradient that reflects this. There is more serotonergic innervation as they travel backwards in this region.Although this innervation pattern is HIGHLY irregular, the people being examined are typically NORMAL in terms of their behavior.Also, bloodflow to this region of the brain has been restored to normal levels....something unexpected because they already know that serotonin receptor density is key to blood distribution.So what is going on here? How can bloodflow be restored when the serotonin innervation is irregular?We don't know.Perhaps other cell types in this region of the brain are being modified to compensate.Maybe one day we will know.Until then, the massive amounts of research on MDMA may help elucidate the risks associated with SSRIs.I hope my verbose theory helps those wondering why this is happening to them....and why extra serotonin causes anxiety.I myself noticed that taking 5-htp makes me feel worse!I concluded that I wasn't suffering a simple shortage of serotonin as a result.Instead, we are all suffering a shortage of storage capacity. Until enough new axons pop up, we will not have anywhere to put this stuff...Ok. I think I'm done.Sorry to those who have a hard time reading so much rambling. I hope my analogies are correct. And I hope I can help some of you.Until next time...Sam Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2011 Report Share Posted April 7, 2011 Hmmm. I have parts here where I agree with you and disagree with you. The sexual attraction started coming back slowly BEFORE the piracetam. O that is a sign to me that healing was already taking place. I feel that the pirecetam is facilitating recovery, not MAKING the recovery. Plus I haven't felt any bad side effects from the Piracetam. > > First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you. > I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around. > I truly believe that your recent progress is a REAL sign of eventual recovery. > BUT, I feel obligated to remind you of my experience... > When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks... > > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense? > > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier. > > I hate being the bearer of bad news, but neither of us are cured....YET. > > Now, for the good news. > > I am in the first week of my 4th cycle ON the piracetam. > Being OFF was the reason I stopped emailing the group last week. > However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world. > And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though... > > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks! > > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process. > I was hoping to deliver such news to the group. > > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours. > > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously. > > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain. > I swear to God, people....i'm not crazy. > As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions. > > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there. > > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation. > > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure. > > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia. > The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both. > > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals. > > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there. > Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain. > Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery. > Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process. > > The serotonergic system is one of the most complex structures in the brain and > the nervous system. > But remember, that the majority of your serotonin is NOT in the brain....its in > the gut. > > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain. > I also believe that certain areas of the brain are more susceptible to this > damage. > Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA. > Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas. > The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network. > > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines. > When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected. > The serotonin receptors in the smooth muscle is no longer attached to the > network... > > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body. > > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord. > This results in serotonin being injected into the base of the brain. > The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body. > When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body. > The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region. > > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior. > Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution. > > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular? > We don't know. > > Perhaps other cell types in this region of the brain are being modified to > compensate. > Maybe one day we will know. > > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs. > > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety. > I myself noticed that taking 5-htp makes me feel worse! > I concluded that I wasn't suffering a simple shortage of serotonin as a result. > Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff... > > Ok. I think I'm done. > Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you. > Until next time... > > > Sam > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2011 Report Share Posted April 7, 2011 piracetam is a ridiculous drug. i remember my first week taking it. i was joking with my friends and i started to get teary eyed from laughing and being excited. that use to happen to me before antidepressants, i never experienced that type of joy again until i started the piracetam. and i tried a lot of shit, not even alcohol would make me emotional like it often does to people. piracetam made my mind work better and my emotions stronger, sometimes even too much soo. i think at some point it started to turn on me. i was probably taking to much, or it was because i wasn't taking it with choline. it made me almost over confident. i was witty, clever and so brilliant. i'd be the one the teacher would call on in my brain and behavior class, i had all the answers, i even pointed out errors in my text book. i was never that smart. i think i had a latent intelligence.. in that i had it there, but my brain had trouble assimilating all the information and being able to use it.it was just all jumbled and unorganized. Piracetam solved that problem, and allowed me to put all the pieces together. i craved social contact on it, and i was a lot more popular with people. i regained my appreciation for music. the downside was that it sometimes made me feel weird at times. i always had to be doing something really stimulating or i'd go crazy. it's hard to explain. anyway that's my experience on piracetam. it's almost scary how it can change your personality so much i might've been almost hypomanic on it. im thinking about revisiting it again but i'm not sure > > First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you. > I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around. > I truly believe that your recent progress is a REAL sign of eventual recovery. > BUT, I feel obligated to remind you of my experience... > When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks... > > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense? > > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier. > > I hate being the bearer of bad news, but neither of us are cured....YET. > > Now, for the good news. > > I am in the first week of my 4th cycle ON the piracetam. > Being OFF was the reason I stopped emailing the group last week. > However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world. > And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though... > > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks! > > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process. > I was hoping to deliver such news to the group. > > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours. > > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously. > > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain. > I swear to God, people....i'm not crazy. > As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions. > > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there. > > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation. > > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure. > > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia. > The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both. > > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals. > > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there. > Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain. > Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery. > Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process. > > The serotonergic system is one of the most complex structures in the brain and > the nervous system. > But remember, that the majority of your serotonin is NOT in the brain....its in > the gut. > > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain. > I also believe that certain areas of the brain are more susceptible to this > damage. > Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA. > Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas. > The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network. > > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines. > When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected. > The serotonin receptors in the smooth muscle is no longer attached to the > network... > > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body. > > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord. > This results in serotonin being injected into the base of the brain. > The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body. > When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body. > The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region. > > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior. > Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution. > > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular? > We don't know. > > Perhaps other cell types in this region of the brain are being modified to > compensate. > Maybe one day we will know. > > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs. > > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety. > I myself noticed that taking 5-htp makes me feel worse! > I concluded that I wasn't suffering a simple shortage of serotonin as a result. > Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff... > > Ok. I think I'm done. > Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you. > Until next time... > > > Sam > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2011 Report Share Posted April 7, 2011 Sam & Ben, I have a few questions for each of you since I cam considering trying the Piracetam. Sam - You mention that you have anxiety when you stop taking it. Did you have anxiety issues prior to taking Piracetam that the drug helped alleviate while you were taking it, or, is withdrawal from the Piracetam causing the anxiety? Secondly, this time around are you using Choline? Also, do you do any kind of attack dosing when you start it or do you just start at your usual dose? And, when you stop, do you taper off of it or just stop taking it? Ben -- What doses are you taking and did you do an attack dose? Also, what benefits do you see that are directly attributed to the Piracetam and not the other supplements? Are you seeing benefit, for example, in both your mood and sexual function? > > First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you. > I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around. > I truly believe that your recent progress is a REAL sign of eventual recovery. > BUT, I feel obligated to remind you of my experience... > When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks... > > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense? > > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier. > > I hate being the bearer of bad news, but neither of us are cured....YET. > > Now, for the good news. > > I am in the first week of my 4th cycle ON the piracetam. > Being OFF was the reason I stopped emailing the group last week. > However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world. > And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though... > > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks! > > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process. > I was hoping to deliver such news to the group. > > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours. > > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously. > > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain. > I swear to God, people....i'm not crazy. > As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions. > > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there. > > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation. > > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure. > > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia. > The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both. > > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals. > > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there. > Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain. > Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery. > Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process. > > The serotonergic system is one of the most complex structures in the brain and > the nervous system. > But remember, that the majority of your serotonin is NOT in the brain....its in > the gut. > > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain. > I also believe that certain areas of the brain are more susceptible to this > damage. > Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA. > Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas. > The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network. > > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines. > When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected. > The serotonin receptors in the smooth muscle is no longer attached to the > network... > > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body. > > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord. > This results in serotonin being injected into the base of the brain. > The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body. > When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body. > The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region. > > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior. > Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution. > > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular? > We don't know. > > Perhaps other cell types in this region of the brain are being modified to > compensate. > Maybe one day we will know. > > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs. > > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety. > I myself noticed that taking 5-htp makes me feel worse! > I concluded that I wasn't suffering a simple shortage of serotonin as a result. > Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff... > > Ok. I think I'm done. > Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you. > Until next time... > > > Sam > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 7, 2011 Report Share Posted April 7, 2011 ,Yes there was a LOT of anxiety prior to the piracetam. But for me it was not an SSRI, it was MDMA. There are a LOT of similarities between people recovering from both substances. Both emotional and sexual. I have done lots of research on MDMA and I felt I had information to offer the group here. The scientific knowledge on MDMA does help to elucidate some of the risks of SSRIs. Likewise, the long term recovery of many SSRI users has helped to restore my faith in my own recovery process. I have used information about this group to help others recovering from MDMA.When I began the piracetam it caused a new and faster paced type of anxiety. But once I broke through this anxiety during the first two days, it was SMOOTH sailing from then until the end of the cycle. It really made me feel great. It makes the neurotransmitters FLOW!Coming off the piracetam is a very gradual onset of anxiety. It takes a long time, about a week or two at this point. And the change is so subtle that it sneaks up on me every time. You would think I would be prepared for it after 4 cycles, but it has surprised me each time. I do not notice that I am feeling gray again. Once I do finally start feeling anxiety again, its like I have forgotten about the piracetam cycle altogether. It takes a day of feeling shitty for me to realize what is going on.So the anxiety before the cycle is MUCH worse. After the cycle is nothing compared to it.My choline is in the mail. I will let you know how it goes, but everyone I have talked to says they go together hand in hand. Along with fish oil too...I do NOT use an attack dose. The first day is intense enough on its own. I take very small doses throughout the day...I use less than half a pill per day. By day two or three I am great.If you do the attack dose you will still feel great, but its like a roller-coaster ride first. Why not slow it down? The long term benefits are the same....you don't need the whiplash.Because I take such small doses, I do not taper off. I simply cold-turkey it. I must report to the group that last night I had one of the BEST orgasms I've had in the five months of recovery!The night before was good, but last night was awesome. My orgasm literally kept going and going. A good 15 seconds at least....almost what I'm used to. When I started recovery my orgasms had NO sensation at all. When I started the first cycle of piracetam, they were still mostly absent...maybe 15 percent strength. But the piracetam has always made 'pre-orgasm' sex better. And it MASSIVELY increases semen output! (B-vitamins help too...)Now, I can claim to be at about 70% orgasm strength. But you must remember that it gets better with multiple nights for me. The first night when I have the most semen, it tends to be a little weaker orgasm. Strange, huh?The piracetam will NOT disappoint. But it may take longer for it to affect you that much.Good luck.To: SSRIsex Sent: Thu, April 7, 2011 5:21:45 PMSubject: Re: Holy wow Sam & Ben, I have a few questions for each of you since I cam considering trying the Piracetam. Sam - You mention that you have anxiety when you stop taking it. Did you have anxiety issues prior to taking Piracetam that the drug helped alleviate while you were taking it, or, is withdrawal from the Piracetam causing the anxiety? Secondly, this time around are you using Choline? Also, do you do any kind of attack dosing when you start it or do you just start at your usual dose? And, when you stop, do you taper off of it or just stop taking it? Ben -- What doses are you taking and did you do an attack dose? Also, what benefits do you see that are directly attributed to the Piracetam and not the other supplements? Are you seeing benefit, for example, in both your mood and sexual function? > > First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you. > I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around. > I truly believe that your recent progress is a REAL sign of eventual recovery. > BUT, I feel obligated to remind you of my experience... > When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks... > > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense? > > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier. > > I hate being the bearer of bad news, but neither of us are cured....YET. > > Now, for the good news. > > I am in the first week of my 4th cycle ON the piracetam. > Being OFF was the reason I stopped emailing the group last week. > However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world. > And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though... > > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks! > > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process. > I was hoping to deliver such news to the group. > > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours. > > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously. > > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain. > I swear to God, people....i'm not crazy. > As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions. > > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there. > > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation. > > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure. > > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia. > The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both. > > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals. > > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there. > Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain. > Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery. > Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process. > > The serotonergic system is one of the most complex structures in the brain and > the nervous system. > But remember, that the majority of your serotonin is NOT in the brain....its in > the gut. > > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain. > I also believe that certain areas of the brain are more susceptible to this > damage. > Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA. > Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas. > The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network. > > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines. > When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected. > The serotonin receptors in the smooth muscle is no longer attached to the > network... > > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body. > > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord. > This results in serotonin being injected into the base of the brain. > The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body. > When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body. > The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region. > > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior. > Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution. > > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular? > We don't know. > > Perhaps other cell types in this region of the brain are being modified to > compensate. > Maybe one day we will know. > > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs. > > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety. > I myself noticed that taking 5-htp makes me feel worse! > I concluded that I wasn't suffering a simple shortage of serotonin as a result. > Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff... > > Ok. I think I'm done. > Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you. > Until next time... > > > Sam > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 8, 2011 Report Share Posted April 8, 2011 Bought another supply of piracetam to give this another round. I wonder how different aniracetam is. Pharmacological tests seem to indicate it directly affects nACh, D2 and 5HT2 receptors. It just happens to be about 3x the price. Do you think it would be safe to take it concurrently with the inositol someone suggested in another thread, or should I leave them as separate treatments?Parnate seems to have pooped out, when I figured MAOI's had the ideal method of action to treat my peculiar strain of PSSD. We're moving into 2011 at lightning speed and I'm preparing to scratch another year off the list as "MIA". Just about ready to resign myself to being like this forever. If I could do that, I could finally move on.Subject: Re: Re: Holy wowTo: SSRIsex Received: Friday, 8 April, 2011, 4:21 AM ,Yes there was a LOT of anxiety prior to the piracetam. But for me it was not an SSRI, it was MDMA. There are a LOT of similarities between people recovering from both substances. Both emotional and sexual. I have done lots of research on MDMA and I felt I had information to offer the group here. The scientific knowledge on MDMA does help to elucidate some of the risks of SSRIs. Likewise, the long term recovery of many SSRI users has helped to restore my faith in my own recovery process. I have used information about this group to help others recovering from MDMA.When I began the piracetam it caused a new and faster paced type of anxiety. But once I broke through this anxiety during the first two days, it was SMOOTH sailing from then until the end of the cycle. It really made me feel great. It makes the neurotransmitters FLOW!Coming off the piracetam is a very gradual onset of anxiety. It takes a long time, about a week or two at this point. And the change is so subtle that it sneaks up on me every time. You would think I would be prepared for it after 4 cycles, but it has surprised me each time. I do not notice that I am feeling gray again. Once I do finally start feeling anxiety again, its like I have forgotten about the piracetam cycle altogether. It takes a day of feeling shitty for me to realize what is going on.So the anxiety before the cycle is MUCH worse. After the cycle is nothing compared to it.My choline is in the mail. I will let you know how it goes, but everyone I have talked to says they go together hand in hand. Along with fish oil too...I do NOT use an attack dose. The first day is intense enough on its own. I take very small doses throughout the day...I use less than half a pill per day. By day two or three I am great.If you do the attack dose you will still feel great, but its like a roller-coaster ride first. Why not slow it down? The long term benefits are the same....you don't need the whiplash.Because I take such small doses, I do not taper off. I simply cold-turkey it. I must report to the group that last night I had one of the BEST orgasms I've had in the five months of recovery!The night before was good, but last night was awesome. My orgasm literally kept going and going. A good 15 seconds at least....almost what I'm used to. When I started recovery my orgasms had NO sensation at all. When I started the first cycle of piracetam, they were still mostly absent...maybe 15 percent strength. But the piracetam has always made 'pre-orgasm' sex better. And it MASSIVELY increases semen output! (B-vitamins help too...)Now, I can claim to be at about 70% orgasm strength. But you must remember that it gets better with multiple nights for me. The first night when I have the most semen, it tends to be a little weaker orgasm. Strange, huh?The piracetam will NOT disappoint. But it may take longer for it to affect you that much.Good luck.To: SSRIsex Sent: Thu, April 7, 2011 5:21:45 PMSubject: Re: Holy wow Sam & Ben, I have a few questions for each of you since I cam considering trying the Piracetam. Sam - You mention that you have anxiety when you stop taking it. Did you have anxiety issues prior to taking Piracetam that the drug helped alleviate while you were taking it, or, is withdrawal from the Piracetam causing the anxiety? Secondly, this time around are you using Choline? Also, do you do any kind of attack dosing when you start it or do you just start at your usual dose? And, when you stop, do you taper off of it or just stop taking it? Ben -- What doses are you taking and did you do an attack dose? Also, what benefits do you see that are directly attributed to the Piracetam and not the other supplements? Are you seeing benefit, for example, in both your mood and sexual function? > > First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you. > I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around. > I truly believe that your recent progress is a REAL sign of eventual recovery. > BUT, I feel obligated to remind you of my experience... > When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks... > > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense? > > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier. > > I hate being the bearer of bad news, but neither of us are cured....YET. > > Now, for the good news. > > I am in the first week of my 4th cycle ON the piracetam. > Being OFF was the reason I stopped emailing the group last week. > However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world. > And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though... > > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks! > > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process. > I was hoping to deliver such news to the group. > > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours. > > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously. > > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain. > I swear to God, people....i'm not crazy. > As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions. > > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there. > > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation. > > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure. > > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia. > The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both. > > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals. > > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there. > Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain. > Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery. > Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process. > > The serotonergic system is one of the most complex structures in the brain and > the nervous system. > But remember, that the majority of your serotonin is NOT in the brain....its in > the gut. > > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain. > I also believe that certain areas of the brain are more susceptible to this > damage. > Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA. > Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas. > The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network. > > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines. > When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected. > The serotonin receptors in the smooth muscle is no longer attached to the > network... > > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body. > > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord. > This results in serotonin being injected into the base of the brain. > The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body. > When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body. > The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region. > > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior. > Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution. > > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular? > We don't know. > > Perhaps other cell types in this region of the brain are being modified to > compensate. > Maybe one day we will know. > > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs. > > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety. > I myself noticed that taking 5-htp makes me feel worse! > I concluded that I wasn't suffering a simple shortage of serotonin as a result. > Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff... > > Ok. I think I'm done. > Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you. > Until next time... > > > Sam > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 9, 2011 Report Share Posted April 9, 2011 Hi Sam how are you. I bought some piracetam from Celebral health , do you know if they sell quality stuff. Peace, Adam To: SSRIsex Sent: Thu, April 7, 2011 6:21:45 PMSubject: Re: Holy wow Sam & Ben,I have a few questions for each of you since I cam considering trying the Piracetam.Sam - You mention that you have anxiety when you stop taking it. Did you have anxiety issues prior to taking Piracetam that the drug helped alleviate while you were taking it, or, is withdrawal from the Piracetam causing the anxiety?Secondly, this time around are you using Choline? Also, do you do any kind of attack dosing when you start it or do you just start at your usual dose? And, when you stop, do you taper off of it or just stop taking it?Ben --What doses are you taking and did you do an attack dose?Also, what benefits do you see that are directly attributed to the Piracetam and not the other supplements? Are you seeing benefit, for example, in both your mood and sexual function?>> First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you.> I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around.> I truly believe that your recent progress is a REAL sign of eventual recovery.> BUT, I feel obligated to remind you of my experience...> When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks...> > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense?> > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier.> > I hate being the bearer of bad news, but neither of us are cured....YET.> > Now, for the good news.> > I am in the first week of my 4th cycle ON the piracetam.> Being OFF was the reason I stopped emailing the group last week.> However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world.> And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though...> > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks!> > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process.> I was hoping to deliver such news to the group.> > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours.> > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously.> > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain.> I swear to God, people....i'm not crazy.> As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions.> > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there.> > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation.> > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure.> > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia.> The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both.> > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals.> > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there.> Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain.> Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery.> Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process.> > The serotonergic system is one of the most complex structures in the brain and > the nervous system.> But remember, that the majority of your serotonin is NOT in the brain....its in > the gut.> > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain.> I also believe that certain areas of the brain are more susceptible to this > damage.> Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA.> Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas.> The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network.> > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines.> When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected.> The serotonin receptors in the smooth muscle is no longer attached to the > network...> > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body.> > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord.> This results in serotonin being injected into the base of the brain.> The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body.> When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body.> The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region.> > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior.> Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution.> > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular?> We don't know.> > Perhaps other cell types in this region of the brain are being modified to > compensate.> Maybe one day we will know.> > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs.> > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety.> I myself noticed that taking 5-htp makes me feel worse!> I concluded that I wasn't suffering a simple shortage of serotonin as a result.> Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff...> > Ok. I think I'm done.> Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you.> Until next time...> > > Sam> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 9, 2011 Report Share Posted April 9, 2011 Hey Adam.I'm sure you got the real deal, and that is all that matters. Piracetam is pretty cheap to manufacture.Did you get the choline and fish oil to go with it?If not, you should. And remember, the first few doses can be intense.And to the person that asked about inositol....I plan to take it with my piracetam. I don't see why not, but I may try it on its own first just to see if it 'feels' like anything on its own.From: Adam Ballerini To: SSRIsex Sent: Sat, April 9, 2011 9:18:02 AMSubject: Re: Re: Holy wow Hi Sam how are you. I bought some piracetam from Celebral health , do you know if they sell quality stuff. Peace, Adam To: SSRIsex Sent: Thu, April 7, 2011 6:21:45 PMSubject: Re: Holy wow Sam & Ben,I have a few questions for each of you since I cam considering trying the Piracetam.Sam - You mention that you have anxiety when you stop taking it. Did you have anxiety issues prior to taking Piracetam that the drug helped alleviate while you were taking it, or, is withdrawal from the Piracetam causing the anxiety?Secondly, this time around are you using Choline? Also, do you do any kind of attack dosing when you start it or do you just start at your usual dose? And, when you stop, do you taper off of it or just stop taking it?Ben --What doses are you taking and did you do an attack dose?Also, what benefits do you see that are directly attributed to the Piracetam and not the other supplements? Are you seeing benefit, for example, in both your mood and sexual function?>> First, > > Ben - I am very happy to hear the piracetam has made a profound difference for > you.> I found myself wandering onto paxilprogress last week and discovered many of > your posts there. > > I must say I feel some real sympathy for you, and I am very pleased to hear your > story is turning around.> I truly believe that your recent progress is a REAL sign of eventual recovery.> BUT, I feel obligated to remind you of my experience...> When I stop taking the piracetam I slowly drift back into anhedonia. And > eventually maybe even panic attacks...> > In research involving schizophrenia (something we have a lot in common with) > piracetam improves the patient's condition without actually curing the 'diseased > state'. To me this means there is a structural defect in the brain that does not > change, but is somehow 'bypassed' by this medication. The piracetam makes the > cells more permeable, so if there are neurotransmitters trying to reach nearby > receptors...they are more likely to cross the barrier. > > Make sense?> > Restore the membranes to their previous state, and the neurotransmitters stop > crossing the barrier.> > I hate being the bearer of bad news, but neither of us are cured....YET.> > Now, for the good news.> > I am in the first week of my 4th cycle ON the piracetam.> Being OFF was the reason I stopped emailing the group last week.> However, I was surprised that during this OFF cycle, it took MUCH longer for me > to disconnect from the world.> And even after I did, my 'panic attacks' were much milder. It still managed to > sneak up on me though...> > In the previous 3 OFF cycles, it took me anywhere from 3 days to a week to feel > the anhedonia....both sexually and emotionally. > > This time, it took 2 whole weeks!> > This is a true sign of progress to me. > This is also a confirmation that the use of piracetam is not going to stop or > harm the healing process.> I was hoping to deliver such news to the group.> > I must also report that it took 4 days back ON the drug, to experience relief > again. Before it happened much quicker, usually within the first 12-36 hours.> > I will say that during the first 2 days back ON, my anxiety ramped up big time. > I also got very weird sensations in my lower intestines. I think it is at the > ileum - the valve connecting the small and large intestine. It felt like I had > a WORM crawling around inside me....seriously.> > To go even further....as this worm sensation was crawling around my > intestines....I could feel it tickling in certain parts of my brain.> I swear to God, people....i'm not crazy.> As the intestines begin re-wiring themselves there are very specific increases > in blood flow to certain brain regions.> > It is such a creepy feeling....and it is much more difficult to notice when i am > OFF the piracetam. > > But it is still there.> > I encourage everyone on this email group to pay VERY close attention to the > intestines when they are feeling anxiety. I have noticed several times that when > I have a real panic attack....I feel flushing down below. It is never obvious, > because this is smooth involuntary muscle....but I DO feel it happening. > Especially after a major crying episode....I am more likely to feel a subtle > flushing sensation.> > I guarantee that fasting for several days would bring relief to just about > anyone here that is still experiencing anxiety and head pressure.> > I am also certain that the continual operation of the intestines is at the root > of the healing process as well as the anhedonia.> The intestines are home to the vast majority of serotonin and serotonin > receptors. 95% of both.> > The process of digestion involves both the production of bile and the > contraction of smooth muscle. > > Tryptophan is turned into bile AND serotonin....which is critical for the > contraction of smooth muscle...both in the intestines and the genitals.> > The serotonin receptors in the brain are KNOWN to play a critical role in blood > distribution. > > The more receptors in a section of brain tissue, the more blood vessels you will > find there.> Former users of MDMA, such as myself, have been shown to experience decreases in > blood flow to many regions of the brain.> Some will ALSO experience increases of blood flow to these areas....sometimes > for many months after. > > This is known to be a sign of neurotoxicity AND of recovery.> Amazingly, bloodflow is eventually restored to normal levels in all brain > regions! > > Although it can take more than a year for many patients, and there is a belief > that other cell types, such as GABA receptors are being modified during this > process.> > The serotonergic system is one of the most complex structures in the brain and > the nervous system.> But remember, that the majority of your serotonin is NOT in the brain....its in > the gut.> > I firmly believe that we have all damaged part of the vast connection between > the intestines and the brain.> I also believe that certain areas of the brain are more susceptible to this > damage.> Most likely it would be the areas that are affected positively when we are under > the influence of SSRIs or MDMA.> Unfortunately the emotional and sexual centers of the brain appear to lie within > these more vulnerable areas.> The frontal and prefrontal cortex are innervated by fiber like serotonin > axons....much smaller and possibly more fragile than the rest of the network.> > I believe that these areas are connected to the lower part of the small > intestines....and possibly the large intestines.> When the front of the brain experiences serotonergic damage, the ileum down to > the genitals are disconnected.> The serotonin receptors in the smooth muscle is no longer attached to the > network...> > BUT, the human body does not give up, either. > Unlike other forms of chemical damage, MDMA and SSRI's do NOT cause > gliosis....or scar tissue to form. This allows for axons to re-sprout from the > serotonin cell body.> > I believe that the villi in the intestines are sending constant signals of > irritation....or tickling...up the spinal cord.> This results in serotonin being injected into the base of the brain.> The long branches of the serotonin network start pulsing....as if they were > swelling with the neurotransmitter. > > The cell body itself is immune to the damage done by the drug....so this > pressure is exerted along the whole cell body.> When enough pressure builds up....or cortisol....new axons suddenly sprout from > the cell body.> The axons are more likely to sprout on the cell bodies closer to the back of the > brain. > > After enough axons sprout in the REAR of the brain, the pressure being exerted > on the network begins to target areas closer to the face. This is a back to > front motion. > > > Brain scans (SPECT) show that former MDMA users display a gradient that reflects > this. > > There is more serotonergic innervation as they travel backwards in this region.> > Although this innervation pattern is HIGHLY irregular, the people being examined > are typically NORMAL in terms of their behavior.> Also, bloodflow to this region of the brain has been restored to normal > levels....something unexpected because they already know that serotonin receptor > density is key to blood distribution.> > So what is going on here? How can bloodflow be restored when the serotonin > innervation is irregular?> We don't know.> > Perhaps other cell types in this region of the brain are being modified to > compensate.> Maybe one day we will know.> > Until then, the massive amounts of research on MDMA may help elucidate the risks > associated with SSRIs.> > I hope my verbose theory helps those wondering why this is happening to > them....and why extra serotonin causes anxiety.> I myself noticed that taking 5-htp makes me feel worse!> I concluded that I wasn't suffering a simple shortage of serotonin as a result.> Instead, we are all suffering a shortage of storage capacity. > Until enough new axons pop up, we will not have anywhere to put this stuff...> > Ok. I think I'm done.> Sorry to those who have a hard time reading so much rambling. > > I hope my analogies are correct. And I hope I can help some of you.> Until next time...> > > Sam> Quote Link to comment Share on other sites More sharing options...
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