Re: R: clary sage and oestrogenic activity

[Guest guest]

<<The best place to look are with aroma molecule companies or flavour and fragrance companies who sell tonnes of this stuff to the perfume industry, they would have data sheets on it for sure.Hope this helps.Stuart Fitz >>

Stuart

thank you for the info,

One of the first things I did was to ask a couple of chemist in fragrance companies, because I was aware of the possible conformational similarity, but they have clearly stated that notwithstanding its shape, in their opinion sclareol could not act as an estrogen. Moreover, they have told me that another purpoted estrogenic activity, namely that of anethole, is probably due to impurities in the trans-anethole sample used for the experiment. Nothing was stated as 100% certain, but they were quite positive about it. I'll let you know if I get more detailed info

Marco