Allergy to pig glands but not neccessarily the meat

[Guest guest]

I have read books by several docs who say that they find some patients

exhibit allergic-type responses to Armour. I suspect I did also, as

my throat swelled terribly and it was very difficult to swallow,

resulting in only taking it 3 days.

This study is a possible explanation. While it doesn't specifically

mention thyroid, it would seem logical that if one could tolerate

pork meat fine, but have an allergic response to other parts of the

pig, then it's likely that could also happen with the thyroid.

http://www.ncbi.nlm.nih.gov/pubmed/9756208?dopt=Abstract

1: Clin Exp Allergy. 1998 Aug;28(8):1021-5.

Related Articles, Links

Click here to read

Alimentary allergy to pork. Crossreactivity among pork kidney and

pork and lamb gut.

Llátser R, Polo F, De La Hoz F, Guillaumet B.

Departamento de Medicina Interna, Hospital de Sant Pau i Santa

Tecla, Tarragona, Spain.

BACKGROUND: A patient suffered from anaphylaxis after the

ingestion of pork gut and kidney, but she tolerated pork meat.

Clinical symptoms were also triggered upon intake of lamb gut.

OBJECTIVE: To demonstrate an IgE-mediated hypersensitivity and

identify the pork proteins involved. And also, to study the possible

cross-allergenicity among proteins from lamb gut and pork. METHODS AND

RESULTS: The patient had strong positive skin-prick test responses to

pork kidney, gut and liver, and lamb gut and kidney. RAST technique

showed specific IgE to pork kidney, gut and meat. Immunoblotting after

SDS-PAGE disclosed the presence of four prominent IgE-binding

polypeptides in pork kidney (200, 90, 57, and 47 kDa), two in gut (57

and 27 kDa), and three in meat (51, 40, and 28-30 kDa), apart from

other weaker radiostained bands in each extract. The binding of IgE to

200 and 90 kDa allergens from pork kidney was inhibited by gut from

pork and lamb in immunoblotting inhibition assays. No inhibition was

produced by pork meat. CONCLUSIONS: A mechanism of IgE-mediated

hypersensitivity has been demonstrated in this case of anaphylaxis

provoked by pork products. Four main allergens were detected in pork

kidney, two of which (200 and 90 kDa) share allergenic epitopes with

proteins from pork and lamb gut. On the other hand, pork meat does not

seem to have allergenic epitopes in common with pork kidney.

PMID: 9756208 [PubMed - indexed for MEDLINE]

[Guest guest]

THANK YOU!!! Allergy to pig glands but not neccessarily the meat To: Thyroiditis > I have read books by several docs who say that they find some patients > exhibit allergic-type responses to Armour. I suspect I did also, as > my throat swelled terribly and it was very difficult to swallow, > resulting in only taking it 3 days. > > This study is a possible explanation. While it doesn't specifically > mention thyroid, it would seem logical that if one could tolerate > pork meat fine, but have an allergic response to other parts of the > pig, then it's likely that could also happen with the thyroid. > > http://www.ncbi.nlm.nih.gov/pubmed/9756208?dopt=Abstract >

> 1: Clin Exp Allergy. 1998 Aug;28(8):1021-5. > Related Articles, Links > Click here to read > Alimentary allergy to pork. Crossreactivity among pork kidney and > pork and lamb gut. > > Llátser R, Polo F, De La Hoz F, Guillaumet B. > > Departamento de Medicina Interna, Hospital de Sant Pau i Santa > Tecla, Tarragona, Spain. > > BACKGROUND: A patient suffered from anaphylaxis after the > ingestion of pork gut and kidney, but she tolerated pork meat. > Clinical symptoms were also triggered upon intake of lamb gut. > OBJECTIVE: To demonstrate an IgE-mediated hypersensitivity and > identify the pork proteins involved. And also, to study the possible > cross-allergenicity among proteins from lamb gut and pork. METHODS AND

> RESULTS: The patient had strong positive skin-prick test responses to > pork kidney, gut and liver, and lamb gut and kidney. RAST technique > showed specific IgE to pork kidney, gut and meat. Immunoblotting after > SDS-PAGE disclosed the presence of four prominent IgE-binding > polypeptides in pork kidney (200, 90, 57, and 47 kDa), two in gut (57 > and 27 kDa), and three in meat (51, 40, and 28-30 kDa), apart from > other weaker radiostained bands in each extract. The binding of > IgE to > 200 and 90 kDa allergens from pork kidney was inhibited by gut from > pork and lamb in immunoblotting inhibition assays. No inhibition was > produced by pork meat. CONCLUSIONS: A mechanism of IgE-mediated > hypersensitivity has been demonstrated in this case of anaphylaxis > provoked by pork products. Four main allergens were detected in pork

> kidney, two of which (200 and 90 kDa) share allergenic epitopes with > proteins from pork and lamb gut. On the other hand, pork meat does not > seem to have allergenic epitopes in common with pork kidney. > > PMID: 9756208 [PubMed - indexed for MEDLINE] > > > >