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Re: Glucophage

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Hi, -- it helps control insulin resistance... which can be

associated with thyroid disease, some say. Below is the article

(our) posted a few weeks ago.. it's from Shomon's

site. I have had Diabetic-like symptoms including many of the

symptoms below from the start of my thyroid disease but normal

blood sugar levels, which is why this interests me.

--

Insulin Resistance: A Key to Weight Loss

Thyroid Disease Blog

« Weight Loss: Eat To Live - Not Live To Eat | Main | 2003 Thyroid

Cheers and Jeers -- From Shomon »

January 11, 2004

Insulin Resistance: A Key to Weight Loss

Here's a great reader letter! -- " I've written to you numerous times

before, but most recently to request that you write something

about insulin resistance, hyperinsulinemia and diabetes, and

the connection between these disorders and hypothyroidism. So

I was thrilled to read the " Insulin Resistance " segment of your

recent article entitled Losing Weight with Hypothyroidism. It was

very well-written and I'm sure easy to understand by those that

are unfamiliar with insulin resistance.

I have struggled with Hypothyroidism for 19 years! Without boring

you with details, 2 years ago I adopted a low-carb diet and

exercised religiously to lose 40 lbs, only to have 15 of them

come back recently with no explaination. The addition of a drug

called Glucophage XL (extended release metformin) has helped

tremendously by sensitizing my cells to my own insulin, reducing

the amount of glucose my intestines absorb, and turning down

my liver's glucose production. Lower blood sugar means lower

insulin, which means my body stores less fat, and is now

burning my fat stores for fuel! The 15 lbs are gone! AND....I have

cut my dose of Armour Thyroid in half! Yes, I am still hypothyroid,

but it was the insulin resistance that was causing most of my

symptoms. The weight problem, huge appetite, fatigue, brain

fog, joint pain, bleeding gums, numb feet, yeast infections, low

basal body temperature, easy bruising and slow wound healing

have all been resolved over the past 4 months. AND....my blood

pressure has fallen to within ideal normal ranges, as have my

cholesterol levels!

I hope you continue to educate Thyroid patients and to

encourage them to become active partners in their own medical

care. They need to look beyond the thyroid to rule out another

common cause of these symptoms. They should demand a 4 or

5-hour oral glucose tolerance test that also measures insulin

levels (even if their fasting blood sugar is normal) and settle for

nothing less than the 2-hour test. I know if I hadn't made that

demand, I'd still be complaining to my doctor about my thyroid

and he'd still be telling me I was fine!

> > I've prioritized the changes I'm going to ask to be made next

> > endo. appointment: try Glucophage, try Armour, try other types

of

> > thyroid hormone.

> >

> >

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Thanks for letting me know, . I remember that although I have

many of the same symptoms, I stopped reading when I got to " my blood

sugar is lower. " My blood sugar feels like it's already too low.

Let us know if it helps!

> > > I've prioritized the changes I'm going to ask to be made next

> > > endo. appointment: try Glucophage, try Armour, try other types

> of

> > > thyroid hormone.

> > >

> > >

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Hi and Sheila -- I haven't made a decision to start on

Glucophage, it's just something I want to discuss with my endo.

Don't see her for a month, unfortunately! No, I haven't been

diagnosed with insulin resistance, it's just something I want to

ask about. Seems there has been something a little strange

from the start of my thyroid diagnosis with the sudden

appearance of yeast infections, sensitivity to sugar and some of

these hypoglycemic like reactions, plus the fatigue.

, I feel like my blood sugar is 'low' a lot of the time too..

but I'm kind of assuming if you can feel that, that means you've

just come down from a high, or are used to feeling " high " . I don't

know, just a guess.

On the other hand, people with insulin resistance are supposed

to do well on low carbs, which I most certainly do not. At least, I

could not survive on Atkins.

Anyway, a friend's friend has been plagued with chronic yeast

infections and started a very low dose of Glucophage and it

seems to have helped her. Here's more info. on insulin

resistance and the side effects of Glucophage on Dr. Weil's site:

http://www.drweil.com/app/cda/drw_cda.html-command=TodayQ

A-questionId=94119

He says the side effects are often temporary and the more

severe ones are only a risk if you have kidney/liver disease or

heart failure.

> i'm interested in your decision to start on Glucophage. When I

saw the nurse practitioner at my endo's office last time, that was

one of the suggestions she made to me. I haven't made a

decision at this time. Since she didn't explain much of anything

to me about glucophage, except that it would reduce the chances

of me becoming diabetic, I am not prepared to make a decision

about it.

>

> I also haven't had time to research the drug. Before I can

decide, I'm gonna have to do that.

>

> A medical professional/friend of mine has problems

sugar...been diagnosed with insulin resistance. She said her dr.

recommended glucophage but she's not going to take it

because of the side effects. I have no idea what the side effects

are...still need to learn more about it.

>

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