Hashi... Pearls for patients...

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If your TPOAb titer is elevated and USG findings confirm the

diagnosis, you must be monitored as an " autoimmune thyroiditis "

(Hashi) patient. AUTOantibody, AUTOIMMUN thyroiditis. So clear. AutoAb

production means pathology, it can never be accepted normal. In the

beginning phase, destruction of thyrocytes causes exposure of

prepared/stored T4,T3 hormones in the cells. This term is called as

Hashitoxicosis. It may be misdiagnosed as Graves where the production

of T4,T3 are elevated. Thyroid uptake is increased in Graves, because

of overwork. In Hashi, it is usually normal or depleted. TRAb (autoAb

to TSH receptors) is elevated in % 60-70 of Graves patients. In this

term diagnosis requires high experience to make differential

diagnosis.. Then these autoimmune attacks cause thyroid destruction

and in more than 90% of patients T4,T3 tend to decrease and TSH tends

to rise to upper limit of normal range. Usually colleagues think

that: " T3,T4,TSH " are within normal range. No need for further test.

They do not ask " why TSH tends to touch upper limit? " . This period is

critical. If they would analyze the titers of autoAbs, they could

define the disease earlier. Then destruction exceeds compansation. TSH

stimulation can not increse the titers of T4,T3, then patient

becomes " hypothyroid " . In this late phase autoAbs are checked.

Pearls:

1) Monitor your TSH, if it tends to reach upper limit, evaluate the

possible etiologies (>>90 it's Hashi in adults).

2) Ask the serum titers of TPOAb, TgAb.

3) If you're Hashi and hypothyroid, you have to use L-T4. If you're

not hypothyroid but your TSH exceeds half of the normal range, you

have to use L-T4 again. Why? External support to thyroid causes

resting of cells. So antigenic stimulus is decreased, so titers of

autoAbs decreases mildly (it's approved by many studies).

4) The TSH value of a Hashi must be kept within " half and the lower

1/4 " of normal range.

5) The solely treatment modality to suppress autoimmune war

is " selenium therapy " . Test 200 micg/day of L-Selenomethionine for 6

mo. Monitor the titer of TPOAb. If it decreases, you are a responder

to Se (50% of Hashi patients respond this therapy).

6) If titers of TPOAb go on to elevate, you may stop Se.

7) Do not smoke active/passive (it increases autoAbs).

8) I KNOW MANY PEOPLE WILL SAY OPPOSITE OF THAT. BUT, DO NOT USE PORK

EXTRACTS (LIKE ARMOUR). It is NOT, exactly NOT IDENTICAL. Look at the

molecular weights. It may triggers hypersensitization of immun cells

which are ready to war against to familiar faces. Please read the most

famous pharmacology textbook (Katzung). You know, somon calcitonin

(miacalcic) was used in the treatment of osteoporosis in the past.

This fish hormon was very familiar to human calcitonin. But not same.

Your immun cells can identify the difference. Then, the Abs which are

programmed to destroy these familiars destroys your own calcitonin.

This is well known and it's called as " cross reaction " in immunology.

Now nobody prescribe somon calcitonin, pork insulin etc to HUMAN now.

If you can understand it, you have to reevaluate your datas about

Armour. It's a historical fault. That's all. You can not sell it in

most of European countries. It has a serious potential to

hypersensitize immun cells against to similar molecules like your own

T4,T3,... Why do we use recombinant insulin instead of pig insulin?

Died. Finished. Nonsense. So dangerous. But I've been kicked from a

famous thyroid group for this reason. How do they, I dont know. But

Armour has a good team in these media. USA was land of opportunities

yesterday. But now, it is the land of OPPORTUNISTS. I don't know any

proffesional who can accept these extracts in a scientific congress,

but unfortunatelly, pressure of sponsors, dictate them to prescribe

these primitive drugs. You will see alot of histeric patients who

insist on this " magic powder " . Monitor their AutoAb titers. Remember

my suggestion.

I don't want to read any answer about the " super effects of Armour,

please " . I know hundreds of Hashi patients whose AutoAb titers go on

to decrease with synthetic T4 + selenium. Pig T4 may be used for pigs,

not human. They may claim that if it contains only pure and identical

T4 and T3. False, lie. If it is so, what is difference between

synthetic one? It is not pure, nor identical. And this difference is

dangerous for your immunity.

Finally try to eat more vegetable and raw fruits to get more

antioxidant which increases the resistance of cells.

I've spent 1 hour for this free prescription. I do not sell anything

like others. I do not look for any potential patient to add my file.

Selenium is very cheap and you can find alot of trade marks. So I do

not try to sell it.

I tried to share my experiences with you who are very distant from me.

Hope to see you hapier.

on's Principal of Internal Medicine, Current Medical Diagnosis &

Treatment, Robbin's Pathology, Katzung Pharmacology... are the best

seller textbooks of medicine.