Re: DMSO in combination w/ GABA

[Guest guest]

I Googled GABA +molecular weight and if this is correct it

is 103, which is well under

the 1000 Dalton limit of DMSO. So yes it should be able to

carry it in and pass the BBB.

As far as amounts you could start out with a solution of

DMSO that is comfortable for

you to use on the area that you are planning to apply it to.

30% is tolerated pretty well

by most areas but you still need to check your level of

sensitivity. 20% will still carry it

in but may not hold as much in solution. It's something you

have to work out.

Then add GABA powder a teaspoon or so at a time to a known

amount of 30% DMSO

solution, say one cup and keep track of how much you are

putting in. Keep adding until

no more will dissolve, shaking and allowing time between

additions for it to go into

solution. Keep your notes so that when you want to make it

again. You are obviously

going to exceed the amount that will go into solution to get

to the point of saturation.

You can add more solution at that point and dissolve what

did not dissolve, and then

add the amount that you know will dissolve so that you end

up with two cups of saturated

solution. There is some chance that after sitting it some

could percipitate back out of

solution. In that case I would add about 10% more DMSO solution.

Garnet

kenancy2000 wrote:

>

>

> Hi all,

>

> My question is about using DMSO to get pure GABA powder into the

> bloodstream and past the blood-brain barrier. As I understand it, DMSO

> can pass the blood-brain barrier and take other sustances along with it.

> Because GABA is speculated to have difficulty in permeating this

> barrier, would using DMSO help?

>

> Topically or orally is my main question? And how does one determine the

> percentages of the two substances in mixture.

>

> -Ken

>

>

[Guest guest]

>

> My question is about using DMSO to get pure GABA powder into the bloodstream

and past the blood-brain barrier.

It is much easier and more efficient to open capsules and put the gaba under

your tongue. It is across the blood brain barrier very quickly that way.

Here are instructions:

Q: HOW IS GABA TAKEN?

A: Its peerless design allows for unique sublingual administration. This allows

for superior uptake and utilization. This is of utmost importance where

neurotransmitter amino acids are concerned.

This sublingual application is simple and effective.

Place 3 to 5 grams on your tongue. Immediately the GABA will dissolve. You then

transfer the dissolved GABA solution under you tongue and let it remain there

for 2 to 3 minutes. You can wash the remainder down with some water.

[Guest guest]

I've been trying that with d-ribose, it works like a charm. I read there are

some doubts about whether taking it orally really gets it into the tissues for

them to use it as energy but I figured, why not try it under the tongue. It's

rather pleasant that way, feels cool, tastes ok when you get it away from the

bitter sensing part of the tongue.

> >

> > My question is about using DMSO to get pure GABA powder into the bloodstream

and past the blood-brain barrier.

>

>

> It is much easier and more efficient to open capsules and put the gaba under

your tongue. It is across the blood brain barrier very quickly that way.

>

> Here are instructions:

>

> Q: HOW IS GABA TAKEN?

>

> A: Its peerless design allows for unique sublingual administration. This

allows for superior uptake and utilization. This is of utmost importance where

neurotransmitter amino acids are concerned.

>

> This sublingual application is simple and effective.

>

> Place 3 to 5 grams on your tongue. Immediately the GABA will dissolve. You

then transfer the dissolved GABA solution under you tongue and let it remain

there for 2 to 3 minutes. You can wash the remainder down with some water.

>

[Guest guest]

Where did you read about doubts?

I started taking d-Ribose in fruit juice about a month ago.

The boost in energy was very noticeable.

I blasted through the hills on my bike ride with no difficulty.

Wasn't even tired after.

Made a believer out of me.

I will try this sub-lingual method too.

Del

Re: DMSO in combination w/ GABA

I've been trying that with d-ribose, it works like a charm. I read there are some doubts about whether taking it orally really gets it into the tissues for them to use it as energy but I figured, why not try it under the tongue. It's rather pleasant that way, feels cool, tastes ok when you get it away from the bitter sensing part of the tongue.

..

[Guest guest]

Ken -

please do further research before applying GABA.

Gamma-Aminobutyric Acid (GABA) Stimulates Pancreatic Cancer Growth

http://cancerres.aacrjournals.org/cgi/content/abstract/67/20/9704

+ 221.000 hits in Google for Gamma Aminobutyric acid cancer.

(14.800 hits in Google Scholar).

Regards

At 18:37 Uhr +0000 04.09.2009, kenancy2000 wrote:

>Hi all,

>

>My question is about using DMSO to get pure GABA powder into the

>bloodstream and past the blood-brain barrier. As I understand it,

>DMSO can pass the blood-brain barrier and take other sustances along

>with it. Because GABA is speculated to have difficulty in

>permeating this barrier, would using DMSO help?

>

>Topically or orally is my main question? And how does one determine

>the percentages of the two substances in mixture.

>

>-Ken

>

[Guest guest]

- Your article sent me to do more research. I found other articles

discussing gaba to control, rather than cause, cancer:

http://www.ncbi.nlm.nih.gov/pubmed/19509127?log$=activity

http://www.ncbi.nlm.nih.gov/pubmed/19131543?ordinalpos=5 & itool=EntrezSystem2.PEn\

trez.Pubmed.Pubmed_ResultsPanel.Pubmed_DefaultReportPanel.Pubmed_RVDocSum

This leads me to believe there is a huge body of research yet to be done. When I

see GABA as both cause and cure, I am curious. That GABA is important in cancer

pathways seems to be obvious from what I am reading.

I am glad you posted what you did, it stirred my curious nature ...gaba's

importance in cancer is fascinating. I had no idea.

Ann

> >Hi all,

> >

> >My question is about using DMSO to get pure GABA powder into the

> >bloodstream and past the blood-brain barrier. As I understand it,

> >DMSO can pass the blood-brain barrier and take other sustances along

> >with it. Because GABA is speculated to have difficulty in

> >permeating this barrier, would using DMSO help?

> >

> >Topically or orally is my main question? And how does one determine

> >the percentages of the two substances in mixture.

> >

> >-Ken

> >

>

[Guest guest]

Hi all,

Thanks for the tips and info.

OK, so I can try sublingul, too.

If I try the DMSO method to carry the GABA across the BBB, is it better to take

dermally, or ingest it?

In either case, how is the ratio of the two substances determined?

-Ken

>

> Hi all,

>

> My question is about using DMSO to get pure GABA powder into the bloodstream

and past the blood-brain barrier. As I understand it, DMSO can pass the

blood-brain barrier and take other sustances along with it. Because GABA is

speculated to have difficulty in permeating this barrier, would using DMSO help?

>

> Topically or orally is my main question? And how does one determine the

percentages of the two substances in mixture.

>

> -Ken

>

[Guest guest]

If you ingest it - with or without dmso- it needs to be digested and

metabolized. If you want it to easily cross the blood brain barrier, forget

ingesting. Go sublingual - or transdermal - I've never heard of anyone doing

transdermal - would like to hear your experience if you do.

> >

> > Hi all,

> >

> > My question is about using DMSO to get pure GABA powder into the bloodstream

and past the blood-brain barrier. As I understand it, DMSO can pass the

blood-brain barrier and take other sustances along with it. Because GABA is

speculated to have difficulty in permeating this barrier, would using DMSO help?

> >

> > Topically or orally is my main question? And how does one determine the

percentages of the two substances in mixture.

> >

> > -Ken

> >

>

[Guest guest]

Only if can find out how the ratios work.

-Ken Bagwell

> > >

> > > Hi all,

> > >

> > > My question is about using DMSO to get pure GABA powder into the

bloodstream and past the blood-brain barrier. As I understand it, DMSO can pass

the blood-brain barrier and take other sustances along with it. Because GABA is

speculated to have difficulty in permeating this barrier, would using DMSO help?

> > >

> > > Topically or orally is my main question? And how does one determine the

percentages of the two substances in mixture.

> > >

> > > -Ken

> > >

> >

>