Guest guest Posted November 21, 1999 Report Share Posted November 21, 1999 FYI. ----------------------------------------------------- From Clinician Reviews® In House - Natural Solution for Early Labor Pain [Clinician Reviews 9(9):111-121, 1999. © 1999 Clinicians Publishing Group and & Wilkins.] ------------------------------------------------------------------------------ -- The hospital and surgical settings are among the most important current growth areas for physician assistants and nurse practitioners. In House: Hospital & Surgical Update covers major advances in hospital and surgical patient management, as reported in peer-reviewed journals as well as at major conferences and symposia. Although In House is designed primarily to address the needs of the growing numbers of surgical and hospital-based PAs and NPs, the information in this feature is of importance to all clinicians. ------------------------------------------------------------------------------ -- Effective relief for the severe low back pain of early labor may be as " natural " as water, report Swedish researchers. However, whether sterile water is injected intracutaneously -- as has been demonstrated previously -- or subcutaneously, treatment carries one significant drawback: intense, transient pain during administration. Of 99 pregnant women, Mårtensson and Wallin randomized 33 to receive four intracutaneous injections of 0.1 mL of sterile, salt-free water; 33 to be given four subcutaneous injections of 0.5 mL of sterile water; and 33 to receive four subcutaneous injections of 0.1 mL of isotonic saline (placebo). Injections were administered in the lumbosacral region during a contraction in the first stage of labor. All women were given nitrous oxide and oxygen to breathe during injections. Both intracutaneous and subcutaneous water injections led to significant reductions in labor pain that lasted for 45 to 90 minutes, the researchers reported recently in the British Journal of Obstetrics and Gynaecology. According to the women's reports of pain using a 10-cm visual analog scale that was administered 10 minutes after treatment, intracutaneous injections led to a 5.0-cm reduction in pain, and subcutaneous injections to a 4.5-cm reduction -- compared with a 1.7-cm reduction in the placebo group. At 45 minutes, the corresponding median reductions in pain were 4.9 cm, 4.0 cm, and 1.0 cm, respectively. Reductions in pain were no longer significant at 90 minutes; but by that time, sample size had decreased dramatically: 1 woman was delivered within 10 minutes of treatment, 8 women within 45 minutes, and 15 women within 90 minutes. Contrary to the researchers' expectations, subcutaneous injections -- the newer route of administration -- were no less painful than intracutaneous injections. Patients given placebo experienced less pain during administration than did patients in the active treatment groups. Nevertheless, the authors write, " If in need of treatment in the future, the women in the two study groups were significantly more enthusiastic about their treatment than those in the placebo group. " Mårtensson L, Wallin G. Labour pain treated with cutaneous injections of sterile water: a randomised controlled trial. Br J Obstet Gynaecol. 1999;106:633-637. Quote Link to comment Share on other sites More sharing options...
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