Guest guest Posted November 15, 2009 Report Share Posted November 15, 2009 Thanks Taffy,I've saved this. Too much of a headache at the moment to read it but will asap, as I've already become convinced that DMSO is a powerful tool.Be well,Léna Hi, Garnet: Further to my response yesterday, I am providing several attachments which offer some insight into the use of DMSO. Hopefully the information will be useful to some of the readers. One of the strongest votes of confidence for me in cautiously….repeat, cautiously using DMSO, was learning that a DMSO solution is used in transporting organs for transplants. Also, after reading (and I do not know where anymore) that castor oil with minute amounts of DMSO has been used on the lids of the eyes of horses to help with cataracts; I was bold enough to try this. Have also used DMSO in combination with unpasteurized honey for eye irritation. I have been waiting to have the money to see the local eye specialist before reporting results because he had told me a year ago that I had just a hint of the start of cataracts. If on my next visit he can tell me there is no sign of cataracts, I will attribute this to the use of DMSO with castor oil and/or honey….I alternate them. After reading the report of the study done in Saudi Arabia, I have used DMSO mixed with black walnut tincture on toenail fungus with great results. This has worked better to eliminate toe nail fungus than any of the many, many other remedies I have tried. Kind regards,Taffy From: Date: November 15, 2009 7:56:19 AM ESTSubject: DMSO DMSO and MSMThe Biochemical Oxygen Transport Pair A new insight into their biochemistry that explains the claims for their wide-ranging health and energy benefits W. Gregg, Ph.D.188 Calle La MontanaMoraga, CA 94556Phone/Fax October 1998Send e-mail to Gregg at dwgregg@...Health NotesAnemia | Anthrax | Antioxidants | Autism| Cancer | Chronic Fatigue and Fibromyalgia Rheumatoid Arthritis | Homosexuality | Eternal Life | Vitamin B12 DeficiencyCrohn's Disease | Crohn's Testamonials | Oxygen Treatment Home Page This paper is for information only. It represents the observations, views and opinions of the author, but is not a recommendation for treatment. Anyone reading it should consult his/her physician before considering treatment. DMSO is a widely used commercial solvent derived from trees (living plants) as a byproduct from the production of paper. There are so many claimed health benefits from its use, one has to wonder if it doesn't perform a similar vital function in the biochemistry of plants. If so, it may be no accident that it can provide such broad ranging health benefits to us. It has been written up in many places such as the recent book "DMSO, Nature's Healer" by Dr. Morton (1993), and by Dr. n Whitaker in his newsletter "Health and Healing" in the August, 1995 issue. It is sold in many if not most health food stores in the US and in most countries around the world. Apparently it is used by millions of people for its health benefit properties. I have also found it has a profound beneficial effect in the treatment of Crohn's Disease as discussed in an earlier Health Note. It is commonly used for treating animals, horses in particular, but the FDA has approved it for only one use for humans, the treatment of interstitial cystitis. Since so many people use it anyway, this has made it a controversial subject. Possibly one reason for this is that no one has ever explained how it works biochemically. If that can be done, it should take it out of the controversial "magic" health benefit classification, and put it on a sound technical foundation. It is the purpose of this Health Note to present my new insight/views into that needed description of the primary biochemical function of DMSO in combination with its spontaneously created oxidized form, MSM.In the Health Note for Crohn's Disease I describe a mechanism where the DMSO stimulates a mechanism that enhances the transport of iron from the intestine to the rest of the cells in the body. This is a very specialized mechanism, which is not the primary health benefit mechanism that will be discussed here. The primary mechanism discussed here is how I believe DMSO, in combination with its spontaneously generated oxidized form, MSM, act as an antioxidant pair, in the same sense as I discuss other antioxidants in the previous Health Note, in other words the biochemistry of how DMSO and MSM act together to enhance metabolism. Oxidation States of DMSOIn the body, DMSO can and does take three different oxidation states. It is useful to think of them as being in equilibrium, with the distribution between them at any point being determined by the localized conditions that exist within the cells. The first oxidation state is DMSO itself which has one oxygen atom attached to the sulfur atom. The other two are 1) dimethyl sulfone, also known as methlysulfonylmethane (MSM), which is DMSO with an additional oxygen atom attached to the sulfur atom, forming a molecule with a total of two attached oxygen atoms, and 2) dimethyl sulfide which is DMSO with the oxygen atom removed, forming a molecule with no oxygen's attached. Both DMSO and MSM have the property of being quite soluble in both oil and water based liquids. However, dimethyl sulfide is hydrophobic and tends to be insoluble in water and soluble in oil-based liquids. DMSO and MSMIt should be mentioned here that dimethyl sulfone, the oxidized form of DMSO, is just the more commonly used chemical name for methlysulfonylmethane (MSM) which is now readily available in health foods stores, and which many claim to greatly enhance energy. According to my theory presented here, DMSO and MSM, which form each other in the body, should be essentially indistinguishable in their biochemical effects. They reach a equilibrium distribution between them that is dependent on the local body chemistry, and is independent of which one you start with. The Metabolic Enhancement (Antioxidant) Mechanism of the DMSO-MSM PairThe metabolic enhancement mechanism of DMSO (or MSM) is that of an exceptionally effective oxygen transport system. This transport system involves only two of the three oxidation forms, DMSO and dimethyl sulphone (also known as MSM). If we consider both DMSO and MSM coexisting in equilibrium within the body, (as they always would no matter which you started with) and recognizing that different parts of the body have different oxidation potentials. Then, as the combination is exposed to a zone of high oxidation potential, DMSO is oxidized to MSM resulting in a new distribution of DMSO and MSM, which is higher in MSM. Then as the combination moves to a zone of lower oxidation potential, the MSM releases its oxygen, delivering it to the metabolic processes, resulting in a new distribution that is higher in DMSO again. The cycle then repeats itself and in doing so, serves as an exceptionally effective oxygen transport system. This system could be operative on a macro scale, enhancing the transport of oxygen from the lungs to the blood, from the blood to the cells, and on a micro scale within the cells transporting high oxidation potential to the lower oxidation potential of the mitochondria where it is used in metabolism. We have a continuously decreasing oxidation potential starting highest at the entry point, the lungs, lower in the blood, lower yet as it enters the cells, continuously lowered in the sequences of the metabolic reactions, and finally lowest of all as it is excreted as carbon dioxide and water, the products of metabolism. The DMSO-MSM system of transport will operate only at the front end, delivering oxygen to the mitochondria. It is unlikely that it will play a significant role after the oxygen has been delivered to the mitochondria and the complex metabolic reaction sequences start.This system is made particularly effective by the feature that both DMSO and MSM are highly soluble in both oil and water. They are also small molecules that will diffuse rapidly. Thus, they both easily and rapidly diffuse through the hydrophilic cell cytoplasm as well as the hydrophobic cell membranes. They have no barriers. To my knowledge, we have no other molecules naturally occurring in our bodies quite like this. Oxygen transport is handled by passing it between different molecules that are hydrophilic in the cytoplasm and hydrophobic in the cell membranes. (Actually, this is handled in part by the transport of free electrons, which can be the equivalent of oxidation potential.)Since we obtain DMSO from a plant source, do plants use it this way? More importantly, is it an important, but unrecognized component we obtain from eating plants that greatly assists our metabolism? It may be no accident that the body develops a garlic smell when one uses DMSO. Could the breakdown of known active components in garlic be a potent plant source of DMSO, which would explain some of the greatly touted health benefits of garlic? These are unanswered but reasonable questions. The "Garlic" Body & Breath Odor from Dimethyl Sulfide Derived from DMSOThe elimination of DMSO and MSM happens not only by excretion in the urine and feces but also by elimination through the lungs and skin in the form of dimethyl sulfide. When DMSO gives up its oxygen atom it forms dimethyl sulfide, which is hydrophobic. Because of its hydrophobic property, it will concentrate not only in the cell membranes but also in the interior regions of the hemoglobin molecule. The exterior of the hemoglobin molecule is hydrophilic and thus can "dissolve" in a aqueous media and be carried in the blood. However, the interior is hydrophobic. Any dimethyl sulfide that is formed will eventually migrate to the interior of the hemoglobin molecule and as such be transported everywhere in the blood. However, it has a high vapor pressure so anywhere the blood vessels come in close contact with air, such as in the lungs and skin, there will be a tendency for the dimethyl sulfide to evaporate off and be released. In this way we get both the "garlic" breath and the "garlic" body odor.In theory, there is another option for the dimethyl sulfide. When it is transported to the lungs where you have the highest oxidation potential, it could be oxidized back to DMSO, go back into solution, and not be released as dimethyl sulfide to the breath. Does this also happen? I believe it does. However, the conversion is not complete and can vary from one individual to the next and from one time to the next for a particular individual. I have encountered some evidence of this happening. Specifically, ill people using DMSO have evidenced a particularly bad breath, as noticed by other family members, and this diminishes greatly as they get well. This opens the possibility of using this as a diagnostic tool of the oxidation potential of the blood in the lungs if it is quantified. Making a quantitative analysis of dimethyl sulfide in the breath is an easy task with the right equipment. However, relating this to disease states requires a systematic study that has not been done yet. Hopefully, this preliminary observation will stimulate some new research. A calculationIn my readings I discovered that MSM has been measured to occur naturally in our bodies (blood) at a concentration of approximately 0.2 parts per million. I decided to do a calculation. As oxygen is transported from our lungs to the mitochondria, it goes through a number of stages with continually decreasing oxidation potential (effective oxygen concentration). This is reported as oxygen partial pressures in mm mercury (mmHg). When it gets to the final storage location in the cells, the myoglobin, the partial pressure is approximately 40 mmHg. I decided to calculate the concentration of oxygen in water (the primary component of the cytoplasm) at this partial pressure. It turns out to be approximately 0.2 parts per million, the same as the natural occurrence of MSM.This is very exciting because it opens up the question as to whether the oxygen transport mechanism presented here hasn't always been operating as part of our oxygen transport system and has gone totally unrecognized. It could also explain why the mitochondria have little difficulty using it. They always have. It would also say that even a large, 200+ pound man would have a total amount of only 0.02 grams in his body and this could still be effective as a significant part of the oxygen transport system. Thus, it is no wonder that an amount of DMSO no larger than a eyedropper full (a few grams) could produce a large enhancement of a person's oxygen transport system. The Biochemical Reasons for the Health Benefits of DMSO (or MSM)Within an individual cell, the oxygen transport system will work to smooth-out differences in oxygen potentials between different organelles lowering the potential for damage in some while making more oxygen available to the mitochondria for metabolism. Of course, the mitochondria has to be able to use the oxygen effectively, which means the multitude of reaction systems employed by the metabolic process must be able to utilize the oxygen. As discussed in the "Antioxidant" Health Note, enzymes supported by a wide range of other antioxidants promote these reactions. Thus, the DMSO-MSM transport system will provide additional energy only if the rest of the system can accept the increased oxygen availability. When they are all working together (as a complete, matched set), I believe that we are looking at a remedy for many degenerative diseases. A First-Line Treatment for A Multitude of Medical Diseases/DisordersOnce it is understood that DMSO ( & MSM) acts as a profoundly effective oxygen transport system, this opens up the opportunity to use this information to treat a multitude of medical disorders, immediate and long term that are caused by a deficiency of oxygen transport. As one example, it has been reported that DMSO is greatly helpful in minimizing the damage from a traumatic brain injury due to a blow to the head or a stroke. Now the explanation as to why it helps is clear. Brain cells, more than any other cells in the body cannot tolerate a lack of oxygen for an extended period of time. The DMSO will enhance oxygen transport to the brain cells until there is sufficient healing to where blood flow and the conventional oxygen transport system is reestablished. Personal ExperienceAs a personal experience, a few months ago I decided to try using DMSO to see if it would help remedy my swollen prostate, (something that is common for someone my age). I had a jar of jelled DMSO and spread a liberal amount on my abdomen over my prostate gland. There seemed to be considerable improvement in my prostate (reduction in swelling), but more relevant to this discussion, I went to play tennis a few hours after applying it, and I felt a very large increase in energy and agility over what I was used to. I have repeated this a number of times since with the same result. Is this a validation of the theory of energy enhancement presented above? I am only one person and thus do not represent a reasonable test. However, I am convinced it does work for me, and it is not just a placebo effect. Potential for Allergic ReactionAs with almost anything, some people are allergic to DMSO, so caution should be exercised in its initial use to test this possibility. Start with one drop and if there is any allergic reaction, don't use it at all. Consult with your physician on this issue.I have wondered why there can be an allergic reaction to such a small molecule and concluded that the most likely answer is that reactive sites that can bond with oxygen may also bond with some protein molecules in the body, forming new molecules that invoke an immunological (allergic) reaction.11/15/03 Update: Dementia HelpI received some emails from a person that illustrate/support the DMSO-MSM oxygen transport theory and its benefit to brain function and dementia. She gave me permission to share them with you on this web page.From: DebbieHi@...Date: Fri, 7 Nov 2003 12:04:28 ESTTo: dwgregg@...Subject: re: my Mom and memory dmsoHi, just looking at the web sites. And...ran across your great site.I have dmso...and use for blood infection, yukky feelings...and yes its great and fantastic with hydrogen peroxide.Ok the question is:My mother is here and sent to me via Dad due to the fact he can't handle her memory loss and confusion anymore. I'm the health nut...smile of the family and taking her in for 3 weeks. Its a struggle ...she had a sudden blood clot 911 scene about 3 yrs....clot in arm...so large the arm exploded! Skin ripped open like paper tearing...and a clot in the gut as large as a melon...and the heart went haywire...ended in a pace maker...and in the brain a black spot was found...Ok, I did an experiment...Gave my mom some liquid dmso in juice...half tsp. and within an hour...a new woman!...She could have conversation, laugh, be alert. not exhausted, stopped yawning nonstop...the look of senile confusion left. Yes, some cognitive tasts still rough...the dmso wore off....and then back to the fatigued, yawning and disorientated person...not remember a hoot...short term memory...goes!So, I gave some more dmso...maybe a whole tsp....and within an hour she came alive...again...and could use the bathroom, dress her self, old conversation have energy....Oxygen must be getting to her brain!!!!!!!!!! Praise God. She is only a beautiful...69...this blood cloot ordeal happened...3 years ago.If you could see her...she is so pretty...and her love for life and thankfulnes just comes alive after dmso.Please help me....am I right for thinking this...oxygen got thru to her brain! Will this continue to help her and even heal up the damage..mmm.The dr. hear heard this story and wanted me to immediately put on a hyperbaric treatment program.Then chelation...mouth is full of silver and gold teeth...I hope you can help me asp. I only have my mom for one more week...I will for sure send her home with dmso...or have Dad order from you? And is this legal in Mich. and I'm in Oklahoma where its legal...I love it personally.Sincerely,DebbieMy ResponseFrom: david gregg dwgregg@...Date: Fri Nov 7, 2003 2:58:18 PM US/PacificTo: DebbieHi@...:Re: my Mom and memory dmsoDebbie,Wow! What a wonderful testimony. It definitely makes sense in that the DMSO transports oxygen in the blood where her hemoglobin apparently isn't. She must be anemic. Read my web page on anemia: www.krysalis.net/anemia.htmYou need to correct the anemia and then the DMSO won't be needed so often. As described (the way I do it for myself), get a glass eyedropper bottle (2oz). Add (about) 10 B12, 10 folic acid and 4 multiple vitamin tablets. Fill with DMSO & shake periodically. Takes about 3 days for pills to fall apart. Let sludge settle and apply eyedropper load of clear liquid to insensitive skin. I use the outside of my forearm. It will absorb through the skin and within about one hour she will feel wonderful. You may want to use it every day for a few days but then once a week or once a month. You will soon notice that the up feelings will start to last much longer than when DMSO alone is used. This works because B12 and folic acid are required for the body to synthesize hemoglobin and her intestine is not absorbing them properly.Please give me permission to add your email, with or without your name as you wish (if you want it protected) to my DMSO web page. It is too perfect an illustration to not share with others.Debbie's Update-1From: DebbieHi@...Date: Sat, 8 Nov 2003 22:06:13 ESTTo: dwgregg@...Subject: re: Mom, dementia in OK.What a wonderful letter. Thank you for writing. I have my Mom in bed next to me at the computer...in our office. She had a wonderful day ...on DMSO. Yes, I really think she is B 12 deficiant...One day I gave her a bunch of b 12 and the DMSO together...and it was wonderful. Yes, it does wear off and I was so concerned about the wear off. My Mom and I are so happy now after reading your e mail tonight. It was so such a blessings. Our whole family is pulling for her here at my house. We love her so much. Yes, you may use my e mail to you for the website but please correct the spelling and such due to my hurriedness...at my husband's office.I am amazed...I prayed and we stood on the fact that God wants her well...and we have made the decision to fight!...Suddenly the DMSO...idea came to me and the rest is history...that brown bottle in the cupbd. was a miracle to my mother.I will go to you anemia website now and read to my Mother. She is so happy that you wrote back and it gives such hope. This may be the answer...and not chelation?Or...??? We will give the DMSO and B vit theory a real GO! I will stay in touch with you and hopefully...in a few days ..I will sit Mom down and let her write to you herself.More later and may God richly bless you!!!!!!!!DebbieDebbie's Update-2From: DebbieHi@...Date: Sat, 15 Nov 2003 11:02:14 ESTTo: dwgregg@...Subject: re: Mom with dementiaThank you.I have so much to tell. Mom has been doing fantastic! She flew home and Dad was amazed at how well she was doing!I have a ton to tell.I will call you , Ok?...This is all so amazing.Do you have other testimonials?I have added this mineral...Germanium. Look up dmso/germanium regarding dementia/alz.I mean it...my Mom's life has turned around.Dad was even checking out alz. homes for Mom while she was staying here with me.I'm in Ok and they are in Mich.More later.I will just have to talk with you. God is so good.Bless you and have a wonderful weekend...YaHoo!!!!!!Sincerely,Debbie Health NotesAnemia | Anthrax | Antioxidants | Autism| Cancer | Chronic Fatigue and Fibromyalgia Rheumatoid Arthritis | Homosexuality | Eternal Life | Vitamin B12 DeficiencyCrohn's Disease | Crohn's Testamonials Home Page W. Gregg, Ph.D.188 Calle La MontanaMoraga, CA 94556Phone/Fax Send e-mail to Gregg at dwgregg@... <mime-attachment.gif><mime-attachment.gif>H1 { TEXT-ALIGN: center; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #000000; FONT-SIZE: 36px}H2 { TEXT-ALIGN: center; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #000000; FONT-SIZE: 24px}author { FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #000000; FONT-SIZE: 12px}.center_italic { TEXT-ALIGN: center; TEXT-TRANSFORM: capitalize; FONT-VARIANT: normal; FONT-STYLE: italic; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #000000; FONT-SIZE: 14px; FONT-WEIGHT: normal}.center14text { TEXT-ALIGN: center; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #000000; FONT-SIZE: 14px}.paraboldblue { FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #0000ff; FONT-SIZE: 14px; FONT-WEIGHT: bold}LI { TEXT-ALIGN: justify; LIST-STYLE-TYPE: decimal; FONT-STYLE: normal; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; 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DISPLAY: block; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #ffffff; FONT-SIZE: 16px; FONT-WEIGHT: bold; TEXT-DECORATION: none; PADDING-TOP: 8px}.navigation_sm { TEXT-ALIGN: center; PADDING-BOTTOM: 8px; BACKGROUND-COLOR: #c3a6a6; FONT-STYLE: normal; PADDING-LEFT: 8px; WIDTH: 160px; PADDING-RIGHT: 8px; DISPLAY: block; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #ffffff; FONT-SIZE: 14px; FONT-WEIGHT: bold; TEXT-DECORATION: none; PADDING-TOP: 8px}.navigation_sm:hover { TEXT-ALIGN: center; PADDING-BOTTOM: 8px; BACKGROUND-COLOR: #fec5a4; FONT-STYLE: normal; PADDING-LEFT: 8px; WIDTH: 160px; PADDING-RIGHT: 8px; DISPLAY: block; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; COLOR: #ffffff; FONT-SIZE: 14px; FONT-WEIGHT: bold; TEXT-DECORATION: none; PADDING-TOP: 8px}.ingredient_list { TEXT-ALIGN: left; DISPLAY: run-in; FONT: 12px Georgia, "Times New Roman", Times, serif; WHITE-SPACE: normal; LETTER-SPACING: normal; VERTICAL-ALIGN: baseline; WORD-SPACING: normal}.ingredient_rt { TEXT-ALIGN: right; DISPLAY: inline; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; WHITE-SPACE: normal; FONT-SIZE: 12px}.ingredient_ctr { TEXT-ALIGN: center; DISPLAY: inline; FONT-FAMILY: Georgia, "Times New Roman", Times, serif; FONT-SIZE: 12px}From: Date: November 15, 2009 7:56:47 AM ESTSubject: DMSO information : Hyperbaric Medicine : Melbourne - Australia Home | About Us | Welcome | HyperMED LOKOMAT NeuroRecovery | HyperMED Treatment Protocols | HyperMED Quick Access | HyperMED MEDIA | HyperMED Newsletters | HyperMED Patient Testimonials | HyperMED Gallery | Oxy-Sports | HyperMED Mission Statement | HyperMED NeuroRecovery Foundation | Contact Us Health Benefits DMSO: Dimethyl Sulfoxide Dimethyl SulfoxideAlso known as: DMSO; Dimethylsulphoxide; RIMSODescriptionDimethyl Sulfoxide is a Sulfuric Compound originally used as an industrial solvent that since the 1960's has been recognized for various therapeutic benefits - its usage has been highly controversial.Health Benefits of DMSODetoxificationDMSO (administered intravenously) facilitates the excretion of excessive accumulated Amyloid (amyloidosis).DMSO (applied topically) protects the body against the toxic effects of X-Rays [scientific research - animals].Excretory SystemDMSO (50% solution applied topically to the Feet) alleviates Foot Odour (Bromidrosis) [observations to date indicate that the longer that the DMSO solution is allowed to remain in contact with the feet, the longer thereafter the Foot Odour subsides].DMSO has been approved by the FDA in the treatment of Interstitial Cystitis (IC) [scientific research - double blind human studies: DMSO markedly improves the condition of 93% of IC patients]:DMSO treatment for IC should be administered by a suitably qualified medical practitioner - the usual treatment protocol involves the administration of a 50% solution of DMSO intravesically (i.e. instilled into the Urinary Tract) every 2 weeks for 2 sessions of 4 treatments each.Immune SystemDMSO helps to alleviate Allergies (by "unfolding" Cell Membranes, DMSO permits more Antigens to attach to Cell Membranes, where they are more effectively neutralized by Antibodies).DMSO significantly lessens Inflammation and swelling by reducing inflammatory exudate and enhancing the development of granulation tissue. DMSO facilitates the movement of Macrophages around and through the body's tissues (by increasing the body's production of Migration Inhibitory Factor [MIF]).MetabolismDMSO deactivates Hydroxyl Free Radicals (DMSO combines with Hydroxyl Free Radicals to form Dimethyl Sulfone and Water which are then readily excreted from the body).Musculoskeletal SystemDMSO (either applied topically or consumed orally) minimizes the damage caused by crushing injuries such as Bruises and pulled or wrenched Muscles :- DMSO is a powerful scavenger of Hydroxyl Free Radicals which are responsible for much of the damage caused in these injuries.- If DMSO is applied quickly to an injury it is possible to eliminate entirely any Bruising.DMSO alleviates Rheumatoid Arthritis (by deactivating Hydroxyl Free Radicals which are one of the principal causes of the Inflammation and Pain associated with Rheumatoid Arthritis).Nervous SystemDMSO (DMSO/Amino Acid Combination) therapy partially reverses some of the abnormalities that occur in Down's Syndrome [scientific research - humans: DMSO/Amino Acid therapy causes a tendency towards accelerated maturity in Down's Syndrome children treated, with marked progress in language integration. In some cases, this therapy causes the physical appearance of Down's Syndrome children to more closely resemble that of normal children].DMSO markedly reduces the formation of the abnormal Antibodies that are characteristic of Myasthenia Gravis [scientific research - animals: note that this finding has not yet been confirmed for humans]:- As a secondary means of alleviating Myasthenia Gravis, DMSO also inhibits the actions of Cholinesterases (similarly to the Anticholinesterase Pharmaceutical Drugs employed by orthodox medicine in the treatment of Myasthenia Gravis).DMSO alleviates Pain by impeding the conduction of Nerve Impulses relating to the Pain sensation in the smaller Nerve Fibers.DMSO (1 gram per kg of body weight administered intravenously in a 40% solution within 1 hour of the occurrence of quadriplegia) helps to prevent Paralysis following injuries to the Brain or Spinal Cord (by inhibiting the Free Radical damage that causes Paralysis) [scientific research].DMSO (1 gram per kg of body weight administered intravenously into the Spinal Cord in a 40% solution within 1 hour of the occurrence of quadriplegia) helps to prevent Paralysis following injuries to the Spinal Cord that would otherwise cause Quadriplegia [scientific research - animals & humans: this treatment often results in total avoidance and reversal of paralysis/quadriplegia].DMSO (administered intravenously within 4 hours, and preferably within 90 minutes of its occurrence) helps to prevent the after-effects (including Paralysis) following (the Embolic and Hemorrhagic forms of) Stroke [scientific research - animals].Respiratory SystemDMSO (placed directly into the nostrils) can open the blocked Sinuses that are associated with Sinusitis [scientific observation -humans: relief occurs within minutes].SkinDMSO (applied topically) alleviates the lesions that occur as a result of Herpes Zoster (Shingles).DMSO (applied topically) helps to dissolve the (skin) tissues involved in Scarring [scientific research - humans: a concentration of 50-80% DMSO applied topically 3 times per day flattens raised external scars after several months - microscopic examination of the skin will reveal loosening of Collagen bundles].DMSO (applied topically) potently alleviates Scleroderma (where Scleroderma affects the Skin).DMSO Enhances the Function of these SubstancesDMSO enhances the bioavailability of many substances (it has the capability to transport many therapeutic substances across the body's Cell Membranes without altering the integrity of Cell Membranes). By increasing their bioavailability, DMSO permits a lower dosage of some drugs than would otherwise be required.EnzymesDMSO inhibits the release of Cholinesterases (i.e. it possesses similar properties to Pharmaceutical Anticholinesterases).HormonesWhen exogenous forms of endogenous Steroids (including Testosterone and the Hydrocortisone form of Cortisone) are dissolved in DMSO prior to topical application, their topical bioavailability increases by 300% [scientific research - humans].Immune System ChemicalsDMSO can enter Cells to prime or activate the sub-cellular mechanisms involved in the production and release of Migration Inhibitory Factor (MIF) and in addition, produces a cofactor that enhances MIF or has MIF-like activity.NeurotransmittersDMSO facilitates the transport of (supplemental) Gamma Aminobutyric Acid (GABA) across the Blood-Brain Barrier (without DMSO as a carrier-vehicle, GABA poorly crosses the Blood-Brain Barrier).Pharmaceutical DrugsDMSO enhances the bioavailability and effectiveness of many Anti-Viral Pharmaceutical Drugs (DMSO facilitates their transport directly across Cell Membranes into Cells where they are most potent against Viruses).DMSO facilitates the absorption of Penicillins - i.e. Penicillins can be dissolved in DMSO and applied topically where they are efficiently transported across the Skin.These Substances Enhance the Function of DMSOAntioxidantsAntioxidants counteract DMSO's tendency to convert to Sulfoxide Free Radicals. Side Effects of DMSO TherapyExcretory SystemDMSO (temporarily) causes Halitosis in the form of a garlic-like odor of the breath (this odor is very unpleasant and appears to be the major practical drawback in the usage of DMSO).Free RadicalsAfter chemically reacting with Hydroxyl Free Radicals, DMSO is converted to a Sulfoxide Free Radical.SkinItching is a common side effect of topical DMSO therapy - this side effect can usually be avoided by diluting the concentration of DMSO. Skin Rashes are a common side effect of topical DMSO therapy - this side effect can usually be avoided by diluting the concentration of DMSO.Myths DispelledEyes/EyesightDMSO is often avoided by orthodox medical practitioners due to UNFOUNDED fears that it can cause Cataracts and other changes within the human Eye:- This aspect of DMSO toxicology has been extensively tested in both animals and humans: the results clearly show that DMSO does NOT cause Cataracts in humans even at extremely high dosages for periods up to two years. No adverse changes were found in human or monkey eyes after prolonged, high levels (up to 30 times the usual dosage) of DMSO treatment.- The myth regarding DMSO's toxicity to human Eyes arises from toxicology studies that show that DMSO DOES cause Cataracts and other changes in the Eyes of both dogs and rabbits, however the toxicity of DMSO to the eyes of these animals definitely differs from that of humans.BioavailabilityDMSO has the ability to pass through every tissue and Cell Membrane of the body except the Enamel of Teeth, fingernails and Hair without destroying the integrity of these tissues and Cell Membranes (i.e. it is a membrane penetrate). DMSO also permits the passage of a number of compounds across the barriers of Cell Membranes.DMSO is readily absorbed when administered topically onto human Skin - peak levels occur after 4-8 hours. Topical administered DMSO is slightly less bioavailable than orally ingested DMSO.Orally ingested DMSO is also rapidly absorbed and reaches a blood serum peak in 4 hours and becomes undetectable after 120 hours.DMSO readily crosses the Blood-Brain Barrier (this property of DMSO allows its utilization as an effective vehicle for transporting other substances that may not normally cross the Blood-Brain Barrier).DMSO is excreted from the body partly in an unchanged state and partly as its metabolite - Dimethyl Sulfoxone (DMSO2).DMSO as part of the Global Sulfur CycleDMSO is an intermediate product of the methyl-S-methane global Sulfur cycle which distributes bioavailable Sulfur for all animal and plant life. Approximately 85% of Sulfur (for life) is derived from the pathway:- Sulfonium Salts > Dimethylsulfide > Dimethyl Sulfoxide (DMSO) > Methylsulfonylmethane (MSM)- Sulfonium Salts (produced by phytoplankton in Water) yield the volatile thioether named Dimethylsulfide which is released into the upper atmosphere.- Sunlight catalyzes the oxidation of Dimethylsufide to DMSO.- DMSO is further oxidized in the upper atmosphere (by Sunlight) to form MSM.- This MSM is then concentrated into raindrops which return to the surface of the earth.- Plants absorb and accumulate this MSM (and use some of this MSM for bulding Sulfuric compounds).Forms of DMSODMSO is manufactured in liquid and gel forms.Dosage RecommendationsLong Term Dosage ReductionLess DMSO is required to achieve therapeutic results as time passes (i.e. the cumulative effects of DMSO appear to increase with the passage of time).Topical Therapeutic Dosage ProtocolThe liquid form of DMSO is the most effective form of topical DMSO application, although most people prefer the gel form.Topically applied DMSO is not rubbed onto the Skin but painted or patted on with a thin coating.The concentration of DMSO used in topical treatments should ideally be individualized on a cases by case basis - the optimal concentration varies from 50-80% DMSO.The Face and Neck are more sensitive to topical DMSO than other parts of the body - the maximum concentration of DMSO for application to the Face or Neck should be no greater than 50%.Topical applications of DMSO should not exceed 70% in areas of the skin affected by poor circulation. It is desirable to commence topical DMSO treatment at low concentrations until Skin tolerance builds up.The Skin must be clean, dry and unbroken before topical application of DMSO.Aloe Vera gel is an excellent remedy for the temporary Skin irritation that sometimes occurs as a result of topical DMSO therapy.Oral DMSO Dosage ProtocolThe usual oral dosage of DMSO is 1 - 2 teaspoons (5 - 10 ml) per day.Oral DMSO is normally mixed with Tomato juice or Grape juice to mask its "foul" taste.Intravenous Injections of DMSO Dosage ProtocolUp to 20 cc DMSO that has been diluted to a 25% concentration with sterile water is often administered via intravenous injection by suitably trained physicians for the treatment of the more serious degenerative diseases.Injected DMSO is not administered by infusion or by the drip technique but is administered by the "slow push" method which involves a slow push into the bloodstream all at once.Intravenous Drip DMSO Dosage ProtocolThe slow intravenous drip method is applied over a 2-3 hour period. It involves the addition of 50-100 cc DMSO to a 500 cc glucose or saline solution, dripped into a vein in the patient's arm. This method should only be administered by a suitably qualified physician.Commercial Availability of DMSOIndustrial Grade DMSOCaution: many of the industrial grade DMSO solutions intended for use as solvents have an acid or Acetone contamination of several percent. Acetone contamination can lead to serious medical consequences - because of its small molecular weight, Acetone is readily carried into the blood by Acetone-contaminated DMSO.Source of Commercial DMSOIn the USA, commercially manufactured DMSO is derived from Lignin.DMSO/Water CombinationsBrand Composition DescriptionRIMSO-50: 50% DMSO50% Water Pure pharmaceutical grade DMSO manufactured by Terra Pharmaceuticals Inc. of Buena Park, California.Supplied in 50 cc vials.Domosa: 90% DMSO10% Water Pharmaceutical grade DMSO suitable for injection or for further dilution with water for topical or oral ingestion.Supplied in pint bottles and in gallon bottles for veterinary use.Dimexide: Brand name for DMSO in Russia.DMSO/Amino Acid CombinationsBrand Country Available DescriptionAkron:Merinex: ArgentinaChile DMSO combined with Amino Acids (Gamma-Aminobutyric Acid [GABA], Gamma-Amino-Beta-Hydroxybutyric Acid [GABOB] and Acetylglutamine).5 ml ampoules (for intramuscular injection) and capsules (for oral administration).The dosage protocol for DMSO/Amino Acid combinations involves one intramuscular injection every 2nd day and 2 or 3 capsules orally each day. Injections are suspended every 40 days for a rest period of 1 month during which capsules are still used. This program of treatment normally lasts for 1 year.Akron and Merinex are not approved by the FDA for use in the USA.Vasoactive DMSO CombinationsIpran is the trade name of a vasoactive DMSO product, however this product has not been approved for use in the USA.DMSO's Chemical StructureThe DMSO molecule is ten-sided with a center occupied by a Sulfur atom. It contains two methyl groups - an oxygen atom and a nonbinding electron pair - located at the points of the tetrahydron.Molecular weight: 78.15Freezing point: 68 degrees Fahrenheit BODY { LINE-HEIGHT: 150%; MARGIN: 7px 2px; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: #003366; FONT-SIZE: 8.5pt}BODY { FONT-FAMILY: verdana; FONT-SIZE: 10px}TD { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: #003366; FONT-SIZE: 8.5pt}P { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: #003366; FONT-SIZE: 8.5pt}CITE { TEXT-INDENT: 15pt; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: #003366; FONT-SIZE: 8.5pt}LI { PADDING-BOTTOM: 5pt; FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: #003366; FONT-SIZE: 8.5pt}H1 { FONT-VARIANT: normal; FONT-FAMILY: Verdana; LETTER-SPACING: 1px; COLOR: #003366; FONT-SIZE: 14pt}H2 { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; COLOR: #003366; FONT-SIZE: 14pt; FONT-WEIGHT: normal}H3 { FONT-FAMILY: Verdana, Arial, Helvetica, sans-serif; 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Guest guest Posted November 15, 2009 Report Share Posted November 15, 2009 Taffy, Malware writers, aka spammers, LOVE attachments as they are able to insert their malware into them for their victims to distribute to their cyber contacts. I have spent too much money over the years having attachment sourced virii removed from my PC. Use your emailer Help to learn how to put whatever is in your attachments, into your main message body AS PLAIN TEXT. This simple effort neutralizes malware. Its usually a simple Copy | Paste. If you do not know what a main message body is, you are now reading from mine. Better yet. If the information is found at a website, just post the web address. This minimizes cyber resources. wahoogroups isn't always up to date with malware filters. Maybe Garnet has no problem endangering her subscribers, but, I do not need to spend more money having techies remove malware. And, yes, I do run the best spam filters on my PC. Nuff said. Now, Taffy, once you have done the right thing with your information, please repost. I look forward to reading it. Bruce Chesley Truth is a terrible cross to bear. Tyranny, like hell, is not easily conquered. - Paine The more corrupt the state, the more numerous the laws - Tacitus Treason for $$$$. ALL " pro 2A " orgs. Date: Sun, 15 Nov 2009 05:10:52 -0800 Hi, Garnet: Further to my response yesterday, I am providing several attachments which offer some insight into the use of DMSO. Hopefully the information will be useful to some of the readers. [snip] Kind regards, Taffy ____________________________________________________________ Diet Help Cheap Diet Help Tips. Click here. http://thirdpartyoffers.juno.com/TGL2141/c?cp=pKH27KG0OIw5AzRnm7ZzTAAAJ1DIyk3Ela\ L5nS9SI9EfWI19AAYAAAAAAAAAAAAAAAAAAADNAAAAAAAAAAAAAAAAAAAYQAAAAAA= Quote Link to comment Share on other sites More sharing options...
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