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Re: Biopein Natural Preservative

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In a message dated 2/25/03 2:51:22 PM Alaskan Standard Time,

jenwelch@... writes:

> I contacted Bio-Botanica for a sample and

> literature on this product. It came today. The flyer that came with it

> states:

>

>

Did they tell you anything about cost? I wrote to them, too, but they seem

to be ignoring me. Hmmm...maybe I should have made up a business name for

their form. Ya think?

Sage

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Maurice, after you sent this in, I contacted Bio-Botanica for a sample and

literature on this product. It came today. The flyer that came with it

states:

Introduction:

Biopein, exclusively from Bio-Botanica, is a natural preservative and

stabilizing ingredient. It has been shown to possess potent antimicrobial

properties, making is an ideal ingredient for different natural cosmetic

applications.

Antimicrobial Study:

Biopein's antimicrobial activity was tested against an array of

microorganisms with different spectral susceptibilities. The organisms

included gram positive Staphylococcus aureus, gram negative Escherichia

Coli, Salmonella typhimurium, Klebsiella pneamoniae and Pseudomonas

aeruginosa, acid-fast bacterium Mycobacterium smegmatis and the yeast

Candida albicans. For comparison, the following well-known synthetic

preservatives were used: viz. Phenoxyethanol, Phenylethyl alcohol and a

combination of Methyl/Propylparabens in ration 5:4. The Minimum Inhibitory

Concentration (MIC) was determined for each agent. Biopein had the lowest

MIC (0.3%) demonstrating its activity as a potent inhibitor for various

organisms.

Conclusion:

When looking to preserve and stabilize natural cosmetic product

formulations, Biopein would be an effective natural alternative to commonly

used synthetic preservatives. The composition preparation and use are

patent pending.

It came with an MSDS and Finished Product Specification but no information

regarding recommended usage levels. I'm going to contact the company

tomorrow and ask for some guidelines, but I'm guessing I might want to try

it at 0.3% to start? The color of this is amber yellow and the odor is

quite strong -- strongly reminiscent of oregano and thyme (two of its

constituents). The odor might be quite hard to mask, perhaps not; but I'm

used to the virtually odorless preservatives I've been using.

I'll keep you posted.

Jen

Maurice wrote:

> Remember, the effectiveness of any preservative system can only be

determined by a challenge test.

>

> Biopein Natural Preservative and Stabilizing Ingredient

> http://www.bio-botanica.com/PR_release/biopein.asp

>

> Hauppauge, New York.Bio-Botanica, a leading manufacturer and supplier of

botanical extracts to the cosmetic and personal care industries since 1972,

is pleased to

> introduce Biopein , a natural preservative and stabilizing ingredient for

natural cosmetic applications. Biopein , a proprietary blend of botanical

extracts, has been shown* to

> possess both anti-microbial and stabilizing properties, making it an ideal

choice when looking for an alternative to synthetic preservatives.

>

> Biopein features a combination of botanical extracts including: Oregano

Leaf (Origanum vulgare), Thyme Leaf (Thymus vulgaris), Cinnamon Bark

(Cinnamomum zeylanicum),

> Rosemary Leaf (Rosmarinus officinalis), Lavender Flower (Lavenudula

officinalis) and Goldenseal Root (Hydrastis Canadensis) that, when combined

at proprietary levels, yields

> a natural ingredient (Biopein) with potent organism-inhibiting properties.

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I will let you know this much Jen, I just received an email from Mrs. Singh

and they sell it in 5kg quantities at $239/kilo. I am hoping that was a

misprint, but I can forward the email to you if you wish. Contact me offlist

if interested.

Yoki

I cried unto the Lord with my voice, and He heard me from His holy hill.

Selah

Re: Biopein Natural Preservative

> Maurice, after you sent this in, I contacted Bio-Botanica for a sample and

> literature on this product. It came today. The flyer that came with it

> states:

>

> Introduction:

> Biopein, exclusively from Bio-Botanica, is a natural preservative and

> stabilizing ingredient. It has been shown to possess potent antimicrobial

> properties, making is an ideal ingredient for different natural cosmetic

> applications.

>

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>It came with an MSDS andÿ Finished Product Specification but no information

>regarding recommended usage levels.ÿ I'm going to contact the company

>tomorrow and ask for some guidelines, but I'm guessing I might want to try

>it at 0.3% to start?ÿ The color of this is amber yellow and the odor is

>quite strong -- strongly reminiscent of oregano and thyme (two of its

>constituents).ÿ The odor might be quite hard to mask, perhaps not; but I'm

>used to the virtually odorless preservatives I've been using.

So much for customer service. I'd ask if any challenged tests were conducted

against " well-known synthetic preservatives " .alcohol and a

combination of Methyl/Propylparabens in ration 5:4.

When you ask the vendor about the recommended use levels, you might aslo ask:

What is the maximum recommended level for leave on products?

Can this preservative be used in sun-products?

What safety tests were conducted?

Do you know if Biopein is water soluble or oil soluble?

Maurice

--------------------------------------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

-------------------------------------------------------

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Thanks for the additional pointers on what to ask them, Maurice. My drop

test (on water and olive oil) tells me it is insoluble in water, but

miscible in oils. I dumped the glass of water with two drops of Biopein in

it into the sink. The aroma has filled the kitchen. The smell of this

preservative alone would be enough to deter me from using it in much of

anything. It is very strong!

One additional paragraph on the flyer notes:

Note: Antimicrobial study was conducted in Bio-Botanica's FDA registered,

pharmaceutically licensed facility. A complete copy of the study is

available upon request. For further information see: " Cosmetics &

Toiletries Manufacture Worldwide " , March 2003.

If I'm right in understanding it, the Minimum Inhibitory Concentration of

0.3% would mean that I'd have to use at least 0.3% of this in even a simple

formula for possible preservation, right? In a more complex formula with

proteins and amino acids (like my goat milk lotion), I suspect the level of

use might need to be higher. Peeeeuuuu (is that a scientific word? <g>)

I have to admit, I'm of the " better living through chemistry " crowd, but

wanted to obtain a sample to test anyway.

Here's additional information from the Finished Product Specification sheet

<snipped by me>

Plant and Part Used:

Origanum Vulgare Leaf Extract CAS No: NA

Thymus Vulgaris (Thyme) Leaf Extract CAS No: 84929-51-1

Cinnamonum Zelanicum Bark Extract CAS No: 84649-98-9

Rosmarinus Officinalis (Rosemary) Leaf Extract CAS No: 84604-14-8

Lavandula angustifolia syn: L. Officinalis (Lavender) Flower Extract

CAS No: NA

Hydrastis Canadensis (Goldenseal) Rood Extract CAS No: 84603-60-1

Active Constituents: constituents of above herbs

Appearance: Liquid

Aroma: Characteristic, aromatic

Taste: N/A, for external use only

Method of Manufacture: Extraction by *Bio-chelation® blending

Solvent for Extraction: Alcohol

Additives: None

Recommended Storage: Store in a cool dry place, away from excessive heat,

light or freezing temperatures.

Shelf Life: 24 Months-Unopened

pH: 2.00 - 4.50

*Bio-Chelation® is a registered trademark of Bio-Botanica, Inc.

Bio-chelation® is a proprietary cold extraction process.

Jen

Maurice wrote:

So much for customer service. I'd ask if any challenged tests were

conducted against " well-known synthetic preservatives " <snip>

When you ask the vendor about the recommended use levels, you might also

ask:

What is the maximum recommended level for leave on products?

Can this preservative be used in sun-products?

What safety tests were conducted?

Do you know if Biopein is water soluble or oil soluble?

Maurice

--------------------------------------------------------

Maurice O. Hevey

Convergent Cosmetics, Inc.

http://www.ConvergentCosmetics.com

-------------------------------------------------------

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