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Re: re; Do you recommend patients with CFS receive the pneumococcal

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I had the exact same experience. I responded only weakly to less than half of

the strains. It was only last year, so I'm not sure how long the immunities

will last. I thought it was very interesting that my immune system was LESS

responsive than expected, since I had always thought my CFS was causing my

immune system to overreact.

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<<< I thought it was very interesting that my immune system was LESS

responsive than expected, since I had always thought my CFS was causing

my immune system to overreact.>>>

It can actually be both - typical for CFS is that antigens made of

polysaccharide and lipids are not responded to very well, while those made up of

protein (i.e. tetanus toxoid) are over-responded to. Plus, the initial response

is not crried through the way it is in normal people. It is shut down earlier,

or converted into an IgE )allergic type) response instead of staying as IgG in

the memory cells. The IgE response is not very efficient at handling living

pathogens, but does produce a lot of inflammation, also typical of pwCFS.

 

Gerald R. , Ph.D.

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