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Irritable Bowel Syndrome?

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--- In low dose naltrexone , Destiny <destinyellen@y...>

wrote:

>

> Hi Everyone,

>

> Has anyone used LDN for treating irritable bowel

> syndrome?

>

> Wishing everyone a wonderful Sunday,

>

> Destiny

There is a study that was done a couple of years ago using LDN for

IBS. the results were a 76% success rate which floored the

recsearchers because it came out so high.

Here is an extract of the article from LDN.org

Pain Therapeutics, Inc. trials for Irritable Bowel Syndrome

From the website of Pain Therapeutics, Inc:

Results from a 50-patient pilot study with PTI-901 [0.5mg naltrexone

daily] in men and women were announced in May 2003 and presented at

the American College of Gastroenterology meeting in October 2003. In

this open-label study, patients with IBS reported a 76% response rate

to PTI-901. This response rate was observed in both men and women and

occurred without drug-related safety issues.

In November 2003, we announced the initiation of a Phase III program

with PTI-901. The Phase III program consists of two clinical studies

that are identical in all respects, except for gender. One study will

enroll 600 women and the other will enroll 600 men, all of whom have

been diagnosed with chronic IBS by a gastroenterologist according to

clinically accepted criteria. Each Phase III study is randomized,

double-blinded and will assess the clinical effect of PTI-901 against

placebo during a three-month treatment period.

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